Phase III Randomized Study Of Sorafenib Plus Doxorubicin Versus Sorafenib In Patients With Advanced Hepatocellular Carcinoma (HCC)- CALGB 80802 (Alliance) Abou-Alfa, Ghassan K. , Niedzwieski, Donna , Knox, Jennifer J. ... - ASCO GI - J. Clin. Oncol. - 2016 Abstract - Primary Endpoint - Primary Analysis - GI - CALGB-80802
Long-Term Cardiac Safety Analysis of NCCTG N9831 (Alliance) Adjuvant Trastuzumab Trial Advani, Pooja P. , Ballman, Karla V. , Dockter, Travis J. ... - - J. Clin. Oncol - 2016 Manuscript - Primary Endpoint - Long-Term-Followup Analysis - Breast - N9831
Validating RNAseq-Signatures of Vorinostat (VOR) Sensitivity and Resistance in Patients with Newly Diagnosed Glioblastoma (GBM) Treated with VOR, Temozolomide and Radiation Therapy From Alliance N0874/ABTC-0902. Anderson, S. Keith , Miller, C. Ryan , Sarkaria, Jann N. ... - ASCO - J. Clin. Oncol. - 2016 Abstract - Secondary Endpoint - Primary Analysis - Neuro-Onc - N0874 , ABTC-0902
Effect of Vitamin D Supplementation on Breast Cancer Biomarkers: CALGB 70806 (Alliance) Study Design and Baseline Data Apoe, Ogheneruona , Jung, Sin-Ho , Liu, Heshan , Seisler, Drew K ... - - Am J Hematol Oncol - 2016 Manuscript - Primary Endpoint - Preliminary Analysis - Prevention - CALGB-70806
Patient Reported Outcomes Questionnaire Compliance in Cancer Cooperative Group Trials (Alliance N0992) Atherton, Pamela J , Burger, Kelli N , Pederson, Levi D ... - - Clin Trials - 2016 Manuscript - Primary Endpoint - Primary Analysis - Health Outcome - N0992
Lenalidomide (LEN) maintenance (MNTC) after high-dose melphalan and autologous stem cell transplant (ASCT) in multiple myeloma (MM): A meta-analysis (MA) of overall survival (OS) CALGB 100104 (Alliance) Attal, Michel , Palumbo, Antonio , Holstein, Sarah ... - ASCO - J. Clin. Oncol. - 2016 Abstract - Secondary-not-in-original Endpoint - Primary Analysis - Myeloma - CALGB-100104
Evaluation of mode equivalence of the MSKCC Bowel Function Instrument, LASA Quality of Life, and Subjective Significance Questionnaire items administered by Web, interactive voice response system (IVRS), and paper Bennett, Antonia V. , Keenoy, Kathleen , Shouery, Marwan ... - - Qual Life Res - 2016 Manuscript - Primary Endpoint - Primary Analysis - Health Outcome - NCT01458509
Clinical features and gene- and microRNA-expression patterns in adult acute leukemia patients with t(11;19)(q23;p13.1) and t(11;19)(q23;p13.3) Bhatnagar, B , Blachly, JS , Kohlschmidt, J , Eisfeld, A-K ... - - Leukemia - 2016 Manuscript - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - C8461 , CALGB-20202 , C8525 , CALGB-10102 , CALGB-10201 , CALGB-10503 , CALGB-10603 , CALGB-11002 , CALGB-19808 , CALGB-8923 , CALGB-9120 , CALGB-9222 , CALGB-9621 , CALGB-9720
Persistence of DNMT3A R882 mutations during remission does not adversely affect outcomes of patients with acute myeloid leukaemia Bhatnagar, Bhavana , Eisfeld, Ann-Kathrin , Nicolet, Deedra ... - - Br. J. Haematol. - 2016 Manuscript - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-20202 , CALGB-10201 , CALGB-10502 , CALGB-10503 , CALGB-10603 , CALGB-19808 , CALGB-9222 , CALGB-9621 , CALGB-9720
Testing of candidate single nucleotide variants associated with paclitaxel neuropathy in the trial NCCTG N08C1 (Alliance) Boora, Ganesh K. , Kanwar, Rahul , Kulkarni, Amit A. , Abyzov, Alexej ... - - Cancer Med - 2016 Manuscript - Secondary-not-in-original Endpoint - Primary Analysis - Symptom Inter - N08C1
Phase IB study of sorafenib + evofosfamide in patients with advanced hepatocellular carcinoma (HCC) and renal cell carcinoma NCCTG N1153 (Alliance) Borad, Mitesh J. , Foster, Nathan R. , Martin, Peter R. ... - ESMO GI - Ann. Oncol. - 2016 Abstract - Primary Endpoint - Preliminary Analysis - Experimental - N1153
Identification and resection of the clipped node decreases the false negative rate of sentinel lymph node surgery in patients presenting with node positive breast cancer (T0-T4, N1-2) who receive neoadjuvant chemotherapy – results from ACOSOG Z1071 (Alliance) Boughey, Judy C. , Ballman, Karla V. , Le-Petross, Huong T. ... - - Ann. Surg. - 2016 Manuscript - Secondary-not-in-original Endpoint - Primary Analysis - Breast - ACOSOG-Z1071
Prognostic Effect of Tumor Lymphocytic Infiltration in Resectable Non–Small-Cell Lung Cancer Brambilla, Elisabeth , Le Teuff, Gwénaël , Marguet, Sophie ... - - J. Clin. Oncol - 2016 Manuscript - Secondary Endpoint - Primary Analysis - Respiratory - CALGB-9633
Development of Clinical Precision Medicine Approaches in Meningiomas: Alliance A071401. Brastianos, Priscilla , Shi, Qian , Santagata, Sandro ... - SNOM - - 2016 Abstract - No-Endpoint Endpoint - Trial-Description-Only Analysis - Neuro-Onc - A071401
N107C/CEC.3 (Alliance/NCIC): Phase III Trial of Post-Surgical Stereotactic Radiosurgery (SRS) Compared with Whole Brain Radiotherapy (WBRT) for Resected Metastatic Brain Disease Brown, Paul D. , Ballman, Karla V. , Cerhan, Jane H. ... - ASTRO - Int. J. Radiat. Oncol. Biol. Phys. - 2016 Abstract - Primary Endpoint - Primary Analysis - Neuro-Onc - N107C
Effect of Radiosurgery Alone vs Radiosurgery With Whole Brain Radiation Therapy on Cognitive Function in Patients With 1 to 3 Brain Metastases Brown, Paul D. , Jaeckle, Kurt , Ballman, Karla V. , Farace, Elana ... - - JAMA - 2016 Manuscript - Primary Endpoint - Primary Analysis - Neuro-Onc - N0574
Disease-free (DFS) and overall survival (OS) data from ACOSOG Z1041 (Alliance) a randomized neoadjuvant trial comparing FEC followed by Paclitaxel plus Trastuzumab (FEC → P+T) with Paclitaxel plus Trastuzumab followed by FEC plus Trastuzumab (P+T → FEC+T) in HER2-positive operable breast cancer Buzdar, Aman U. , Suman, Vera J. , Meric-Bernstam, Funda ... - SABCS - Cancer Res. - 2016 Abstract - Secondary Endpoint - Primary Analysis - Breast - ACOSOG-Z1041
Molecular Heterogeneity and Response to Neoadjuvant Human Epidermal Growth Factor Receptor 2 Targeting in CALGB 40601, a Randomized Phase III Trial of Paclitaxel Plus Trastuzumab With or Without Lapatinib Carey, Lisa A. , Berry, Donald A. , Cirrincione, Constance T. ... - - J. Clin. Oncol - 2016 Manuscript - Primary Endpoint - Primary Analysis - Breast - CALGB-40601
Relationship between obesity and clinical outcome in adults with acute myeloid leukemia: A pooled analysis from four CALGB (Alliance) clinical trials Castillo, Jorge J. , Mulkey, Flora , Geyer, Susan ... - - Am. J. Hematol. - 2016 Manuscript - Secondary-not-in-original Endpoint - Comprehensive Analysis - Leukemia - C9621 , C9710 , CALGB-10503 , CALGB-19808
CABOzantinib versus SUNitinib (CABOSUN) as initial targeted therapy for patients with metastatic renal cell carcinoma (mRCC) of poor and intermediate risk groups: results from ALLIANCE A031203 Trial. Choueiri, Toni K. , Halabi, Susan , Sanford, Ben L. , Hahn, Olwen ... - ESMO - - 2016 Abstract - Primary Endpoint - Primary Analysis - GU - A031203
Correlation of high p95HER2:HER2 ratio with poor outcome in two phase II clinical trials of trastuzumab-treated HER2-positive metastatic breast cancer. Chumsri, Saranya , Sperinde, Jeff , Liu, Heshan , Gligorov, Joseph ... - ASCO - J Clin Oncol - 2016 Abstract - Secondary-not-in-original Endpoint - Primary Analysis - Breast - N0337 , N98-32-52
N0436 (Alliance): A phase II trial of irinotecan plus cetuximab in patients with metastatic breast cancer previously exposed to anthracycline and/or taxane-containing therapy Crozier, Jennifer A. , Advani, Pooja P. , LaPlant, Betsy ... - - Clin. Breast Cancer - 2016 Manuscript - Primary Endpoint - Primary Analysis - Breast - N0436
Clinical impact of ABL1 kinase domain mutations and IKZF1 deletion in adults under age 60 with Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL): molecular analysis of CALGB (Alliance) 10001 and 9665 DeBoer, Rebecca , Koval, Gregory , Mulkey, Flora , Wetzler, Meir ... - - Leuk. Lymphoma - 2016 Manuscript - Secondary-not-in-original Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-10001 , C9665
Phase III Trial Evaluating Letrozole As First-Line Endocrine Therapy With or Without Bevacizumab for the Treatment of Postmenopausal Women With Hormone Receptor–Positive Advanced-Stage Breast Cancer: CALGB 40503 (Alliance) Dickler, Maura N. , Barry, William T. , Cirrincione, Constance T. ... - - J. Clin. Oncol - 2016 Manuscript - Primary Endpoint - Primary Analysis - Breast - CALGB-40503
Phase II study of MLN8237 (Alisertib) in advanced/metastatic sarcoma† Dickson, M. A. , Mahoney, M. R. , Tap, W. D. , D'Angelo, S. P. ... - - Ann. Oncol - 2016 Manuscript - Primary Endpoint - Primary Analysis - Experimental - A091102
Adult acute myeloid leukemia with trisomy 11 as the sole abnormality is characterized by the presence of five distinct gene mutations: MLL-PTD, DNMT3A, U2AF1, FLT3-ITD and IDH2 Eisfeld, Ann-Kathrin , Kohlschmidt, Jessica , Mrózek, Krzysztof ... - - Leukemia - 2016 Manuscript - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-20202 , CALGB-8461
CALGB 80403 (Alliance)/E1206: A Randomized Phase II Study of Three Chemotherapy Regimens Plus Cetuximab in Metastatic Esophageal and Gastroesophageal Junction Cancers Enzinger, Peter C. , Burtness, Barbara Ann , Niedzwiecki, Donna ... - - J. Clin. Oncol - 2016 Manuscript - Primary Endpoint - Primary Analysis - GI - CALGB-80403 , ECOG-1206
Accrual of Older Breast Cancer Patients to Alliance Systemic Therapy Protocols over Time: Alliance A151527 (Multiple) Freedman, Rachel A , Seisler, Drew K. , Foster, Jared C. ... - ASCO - J. Clin. Oncol. - 2016 Abstract - Primary Endpoint - Comprehensive Analysis - Older Adult - A151527 , ACOSOG-Z1031 , ACOSOG-Z1041 , C8541 , C9344 , C9741 , CALGB-40101 , CALGB-40302 , CALGB-40502 , CALGB-40503 , CALGB-40601 , CALGB-40603 , CALGB-49907 , CALGB-9342 , CALGB-9840 , N89-30-52 , N9831
Locoregional Recurrence After Sentinel Lymph Node Dissection With or Without Axillary Dissection in Patients with Sentinel Lymph Node Metastases: Long-Term Follow-Up from the American College of Surgeons Oncology Group (Alliance) ACOSOG Z0011 Randomized Trial Giuliano, Armando E. , Ballman, Karla , McCall, Linda ... - - Ann. Surg. - 2016 Manuscript - Secondary Endpoint - Long-Term-Followup Analysis - Breast - ACOSOG-Z0011
Ten-Year Survival Results of ACOSOG Z0011 (Alliance) Giuliano, Armando E. , Hunt, Kelly K. , Ballman, Karla. V. ... - ASCO - J. Clin. Oncol. - 2016 Abstract - Secondary Endpoint - Long-Term-Followup Analysis - Breast - ACOSOG-Z0011
Locoregional Recurrence after Sentinel Lymph Node Dissection with or without Axillary Dissection in Patients with Sentinel Lymph Node Metastases: Long-term follow-up from the American College of Surgeons Oncology Group (Alliance) Z0011 Randomized Trial Giuliano, Armando E , McCall, Linda , Beitsch, Peter ... - ASA - - 2016 Abstract - Primary Endpoint - Long-Term-Followup Analysis - Breast - ACOSOG-Z0011
Impact of neoadjuvant therapy on eligibility for and frequency of breast conservation in stage II–III HER2-positive breast cancer: surgical results of CALGB 40601 (Alliance) Golshan, Mehra , Cirrincione, Constance T. , Sikov, William M. ... - - Breast Cancer Res. Treat. - 2016 Manuscript - Secondary-not-in-original Endpoint - Comprehensive Analysis - Breast - CALGB-40601 , CALGB-40603
Patterns of local-regional management following neoadjuvant chemotherapy in breast cancer: Results from ACOSOG Z1071 (Alliance) Haffty, Bruce G. , McCall, Linda M. , Ballman, Karla V. ... - - Int. J. Radiat. Oncol. Biol. Phys. - 2016 Manuscript - Secondary-not-in-original Endpoint - Primary Analysis - Breast - ACOSOG-Z1071
Impact of radiation on local regional control in women with node positive breast cancer treated with neoadjuvant chemotherapy (NAC) and axillary lymph node dissection (ALND); results from ACOSOG Z1071 (Alliance) Haffty, Bruce , Ballman, Karla , Hunt, Kelly , McCall, Linda ... - ASTRO - Int. J. Radiat. Oncol. Biol. Phys. - 2016 Abstract - Secondary-not-in-original Endpoint - Primary Analysis - Breast - ACOSOG-Z1071
Meta-Analysis Evaluating the Impact of Site of Metastasis on Overall Survival in Men With Castration-Resistant Prostate Cancer Halabi, Susan , Kelly, William Kevin , Ma, Hua , Zhou, Haojin ... - - J. Clin. Oncol - 2016 Manuscript - Secondary-not-in-original Endpoint - Comprehensive Analysis - GU - CALGB-90601
Blood‐based markers of efficacy and resistance to cetuximab treatment in metastatic colorectal cancer: results from CALGB 80203 (Alliance) Hatch, Ace J. , Sibley, Alexander B. , Starr, Mark D. ... - - Cancer Med - 2016 Manuscript - Secondary-not-in-original Endpoint - Primary Analysis - Correl Sci NOS - CALGB-80203
Pharmacogenetic Discovery in CALGB (Alliance) 90401 and Mechanistic Validation of a VAC14 Polymorphism That Increases Risk of Docetaxel-Induced Neuropathy Hertz, Daniel L. , Owzar, Kouros , Lessans, Sherrie , Wing, Claudia ... - - Clin. Cancer Res. - 2016 Manuscript - Secondary-not-in-original Endpoint - Primary Analysis - PPP - CALGB-60404 , CALGB-90401
Neoadjuvant Chemotherapy for Breast Cancer: Functional Tumor Volume by MR Imaging Predicts Recurrence-free Survival—Results from the ACRIN 6657/CALGB 150007 I-SPY 1 TRIAL Hylton, Nola M. , Gatsonis, Constantine A. , Rosen, Mark A. ... - - Radiology - 2016 Manuscript - Secondary Endpoint - Primary Analysis - Breast - CALGB-150007
Genetic prediction of VEGF-A plasma levels in cancer patients CALGB 80303 (Alliance) Innocenti, Federico , Jiang, Chen , Sibley, Alexander ... - AACR - Cancer Res - 2016 Abstract - Secondary-not-in-original Endpoint - Primary Analysis - PPP - CALGB-80303
A Genome-Wide Association Study (GWAS) Of Survival In Metastatic Breast Cancer (MBC) Patients Treated With Letrozole (L) With Or Without Bevacizumab (B) In CALGB 40503 (Alliance) Innocenti, Federico , Owzar, Kouros , Jiang, Chen ... - ASCO - J. Clin. Oncol. - 2016 Abstract - Secondary-not-in-original Endpoint - Primary Analysis - PPP - CALGB-40503
CODEL (Alliance-N0577; EORTC-26081/22086; NRG-1071; NCIC-CEC-2): Phase III randomized study of RT vs. RT+TMZ vs. TMZ for newly diagnosed 1p/19q-codeleted anaplastic glioma. Analysis of patients treated on the original protocol design Jaeckle, Kurt , Vogelbaum, Michael , Ballman, Karla ... - AAN - Neurology - 2016 Abstract - Primary Endpoint - Comprehensive Analysis - Neuro-Onc - N0577
Social Support and Its Implications in Older, Early-Stage Breast Cancer Patients in CALGB 49907 (Alliance A171301) Jatoi, Aminah , Muss, Hyman , Allred, Jake B. , Cohen, Harvey J. ... - - Psychooncology - 2016 Manuscript - Secondary Endpoint - Primary Analysis - Older Adult - CALGB-49907 , A171301
The Effect of Atorvastatin on Breast Cancer Biomarkers in High-Risk Women Ji, YongLi , Rounds, Tiffany , Crocker, Abigail , Sussman, Betsy ... - - Cancer Prev Res (Phila) - 2016 Manuscript - Primary Endpoint - Primary Analysis - Prevention - NCT00914017
The mTORC1 Inhibitor Everolimus Combined with R-CHOP-21 for New Untreated Diffuse Large B-Cell Lymphoma (DLBCL): Safety and Efficacy Results of a Phase I and Feasibility Trial NCCTG 1085 (Alliance) Johnston, Patrick B. , LaPlant, Betsy , McPhail, Ellen ... - - Lancet Haematol - 2016 Manuscript - Primary Endpoint - Primary Analysis - Lymphoma - N1085
Preoperative Modified FOLFIRINOX Treatment Followed by Capecitabine-Based Chemoradiation for Borderline Resectable Pancreatic Cancer Katz, Matthew H. G. , Shi, Qian , Ahmad, Syed A. , Herman, Joseph M. ... - - JAMA Surg - 2016 Manuscript - Primary Endpoint - Primary Analysis - GI - A021101
Impact of Sublobar Resection on Pulmonary Function: Long-term Results from ACOSOG Z4032 (Alliance) Kent, Michael S. , Mandrekar, Sumithra J. , Landreneau, Rodney ... - - Ann. Thorac. Surg. - 2016 Manuscript - Secondary Endpoint - Primary Analysis - Respiratory - ACOSOG-Z4032
A Nomogram to Predict Recurrence and Survival of High-Risk Patients Undergoing Sublobar Resection for Lung Cancer: An Analysis of a Multicenter Prospective Study (ACOSOG Z4032) Kent, Michael S. , Mandrekar, Sumithra J. , Landreneau, Rodney ... - - Ann. Thorac. Surg. - 2016 Manuscript - Secondary-not-in-original Endpoint - Primary Analysis - Respiratory - ACOSOG-Z4032
Impact of Sublobar Resection on pulmonary function; Long-term results from Z4032 (Alliance), a randomized phase III trial Kent, Michael , Fernando, Hiran C , Mandrekar, Sumithra ... - STSA - Ann Thoracic Surg - 2016 Abstract - Secondary-not-in-original Endpoint - Primary Analysis - Respiratory - ACOSOG-Z4032
Determining All-Cause Survival Estimates using ePrognosis in Older Women with Breast Cancer in CALGB 49907 and 369901 (Alliance A151503) Kimmick, Gretchen , Pitcher, Brandelyn , Mandelblatt, Jeanne ... - SABCS - Cancer Res. - 2016 Abstract - Secondary-not-in-original Endpoint - Primary Analysis - Older Adult - A151503 , CALGB-369901 , CALGB-49907
Improved survival of HER2+ breast cancer patients treated with trastuzumab and chemotherapy is associated with host antibody immunity against the HER2 intracellular domain Knutson, Keith L. , Clynes, Raphael , Shreeder, Barath ... - - Cancer Res. - 2016 Manuscript - Secondary-not-in-original Endpoint - Primary Analysis - Breast - N0337 , N98-32-52 , N0938
Surgeon Error In Predicting Stage I Non-Small Cell Lung Cancer (NSCLC) Is A Major Factor Precluding Randomization In CALGB 140503 (Alliance) Kohman, Leslie J. , Gu, Lin , Altorki, Nasser , Veit, Linda J. ... - AATS - - 2016 Abstract - Secondary-not-in-original Endpoint - Primary Analysis - Respiratory - CALGB-140503
Chemotherapy-induced nausea and vomiting: incidence and characteristics of persistent symptoms and future directions NCCTG N08C3 (Alliance) Kottschade, Lisa , Novotny, Paul , Lyss, Alan , Mazurczak, Miroslaw ... - - Support Care Cancer - 2016 Manuscript - Secondary-not-in-original Endpoint - Primary Analysis - Symptom Inter - N08C3
Randomized Phase II Study of Everolimus (E) versus Everolimus plus Bevacizumab (E+B) in Patients (Pts) with Locally Advanced or Metastatic Pancreatic Neuroendocrine Tumors (pNET), CALGB 80701 (Alliance) Kulke, Matthew H. , Niedzwiecki, Donna , Foster, Nathan R. ... - NANETS - Pancreas - 2016 Abstract - Primary Endpoint - Primary Analysis - GI - CALGB-80701
Early relapse of follicular lymphoma after rituximab-based biologic doublet upfront therapy is associated with increased risk of death: a combined analysis from CALGB/Alliance Studies 50402, 50701 and 50803 Lansigan, Frederick , Barak, Ian , Pitcher, Brandelyn , Jung, Sin-Ho ... - ASH - Blood - 2016 Abstract - Secondary-not-in-original Endpoint - Comprehensive Analysis - Lymphoma - CALGB-50402 , CALGB-50701 , CALGB-50803
Association Between Patient Perception of Oncology Clinical Trial Participation and Survival: NCCTG N0392 (Alliance) Le-Rademacher, Jennifer , Dueck Amylou , Chauhan, Cynthia ... - ASCO - J. Clin. Oncol. - 2016 Abstract - Secondary-not-in-original Endpoint - Comprehensive Analysis - Health Outcome - NCCTG-N0392
Association Between Patient Perception of Oncology Clinical Trial Participation and Survival: NCCTG N0392 (Alliance) Le-Rademacher, Jennifer , Dueck, Amylou , Chauhan, Cynthia ... - MASCC / ISOO - - 2016 Abstract - Secondary-not-in-original Endpoint - Comprehensive Analysis - Health Outcome - NCCTG-N0392
Association between DPYD c.1129-5923 C>G/hapB3 and severe toxicity to 5-fluorouracil-based chemotherapy in stage III colon cancer patients: NCCTG N0147 (Alliance) Lee, Adam M. , Shi, Qian , Alberts, Steven R. , Sargent, Daniel J. ... - - Pharmacogenet. Genomics - 2016 Manuscript - Secondary Endpoint - Primary Analysis - Correl Sci NOS - N0147
The genomics of response to neoadjuvant trastuzumab in HER2-positive breast cancer – results from the ACOSOG Z1041 (Alliance) trial Lesurf, Robert , Griffith, Malachi , Griffith, Obi , Watson, Mark A. ... - SABCS - Cancer Res. - 2016 Abstract - Secondary Endpoint - Primary Analysis - PPP - ACOSOG-Z1041
The genomics of response to neoadjuvant trastuzumab and chemotherapy in HER2-positive breast cancer - results from the ACOSOG Z1041 (Alliance) trial Lesurf, Robert , Griffith, Obi , Griffith, Malachi , Trani, Lee ... - PCC - - 2016 Abstract - Secondary Endpoint - Primary Analysis - PPP - ACOSOG-Z1041
Comparative Effects of CT Imaging Measurement on RECIST End Points and Tumor Growth Kinetics Modeling Li, CH , Bies, RR , Wang, Y , Sharma, MR , Karovic, S , Werk, L ... - - Clin Transl Sci - 2016 Manuscript - Secondary-not-in-original Endpoint - Primary Analysis - PPP - CALGB-30203 , CALGB-30303 , CALGB-9730
Identifying Risk Factors For Toxicity In Patients With Hormone-Receptor Positive Advanced Breast Cancer Treated With Bevacizumab Plus Letrozole: A CALGB 40503 (Alliance) Correlative Study Li, Daneng , Dickler, Maura N. , McCall, Linda M. , Hahn, Olwen M ... - ASCO - J. Clin. Oncol. - 2016 Abstract - Secondary Endpoint - Primary Analysis - Older Adult - CALGB-40503
Association of Variants with Bevacizumab-Induced Hypertension Identified by Exome Sequencing CALGB-80405 (Alliance) Li, Megan , Mulkey, Flora , Jiang, Chen , Venook, Alan P. ... - ASCPT - - 2016 Abstract - Secondary Endpoint - Primary Analysis - GI - CALGB-80405
Effect of MR Imaging Contrast Thresholds on Prediction of Neoadjuvant Chemotherapy Response in Breast Cancer Subtypes: A Subgroup Analysis of the ACRIN 6657/I-SPY 1 TRIAL Li, Wen , Arasu, Vignesh , Newitt, David C. , Jones, Ella F. ... - - Tomography - 2016 Manuscript - Secondary Endpoint - Primary Analysis - Breast - ACRIN 6657 , CALGB-150007
Effect of Pretreatment Renal Function on Treatment and Clinical Outcomes in the Adjuvant Treatment of Older Women With Breast Cancer: Alliance A171201, an Ancillary Study of CALGB/CTSU 49907 Lichtman, Stuart M. , Cirrincione, Constance T. , Hurria, Arti ... - - J. Clin. Oncol - 2016 Manuscript - Secondary Endpoint - Primary Analysis - Older Adult - A171201 , CALGB-49907
PAM50 gene signatures and breast cancer prognosis with adjuvant anthracycline- and taxane-based chemotherapy: correlative analysis of C9741 (Alliance) Liu, Minetta C , Pitcher, Brandelyn N , Mardis, Elaine R ... - - NPJ Breast Cancer - 2016 Manuscript - Secondary-not-in-original Endpoint - Primary Analysis - Correl Sci NOS - C9741 , CALGB-159905
Prognostic and Predictive Effect of TP53 Mutations in Patients with Non-Small Cell Lung Cancer from Adjuvant Cisplatin-Based Therapy Randomized Trials: A LACE-Bio Pooled Analysis. Ma, Xiaoli , Le Teuff, Gwénaël , Lacas, Benjamin , Tsao, Ming Sound ... - - J Thorac Oncol - 2016 Manuscript - Secondary-not-in-original Endpoint - Comprehensive Analysis - Respiratory - CALGB-150802 , CALGB-9633
Long-term trajectories of self-reported cognitive function in a cohort of older survivors of breast cancer: CALGB 369901 (Alliance) Mandelblatt, Jeanne S. , Clapp, Jonathan D. , Luta, Gheorghe ... - ICCTF - Cancer - 2016 Abstract - Secondary Endpoint - Primary Analysis - Older Adult - CALGB-369901
Long‐term trajectories of self‐reported cognitive function in a cohort of older survivors of breast cancer: CALGB 369901 (Alliance) Mandelblatt, Jeanne S. , Clapp, Jonathan D. , Luta, Gheorghe ... - - Cancer - 2016 Manuscript - Secondary-not-in-original Endpoint - Primary Analysis - Older Adult - CALGB-369901
Detection of Occult Micrometastases in Patients With Clinical Stage I Non–Small-Cell Lung Cancer: A Prospective Analysis of Mature Results of CALGB 9761 (Alliance) Martin, Linda W. , D’Cunha, Jonathan , Wang, Xiaofei , Herzan, Debra ... - - J. Clin. Oncol - 2016 Manuscript - Primary Endpoint - Long-Term-Followup Analysis - Respiratory - C9761
Aromatase inhibition remodels the clonal architecture of estrogen-receptor-positive breast cancers Miller, Christopher A. , Gindin, Yevgeniy , Lu, Charles ... - - Nat Commun - 2016 Manuscript - Secondary-not-in-original Endpoint - Primary Analysis - Correl Sci NOS - ACOSOG-Z1031
A Phase III, Randomized Double-Blind Study of Doxepin Rinse versus “Magic Mouthwash” versus Placebo in the Treatment of Acute Oral Mucositis Pain in Patients Receiving Head and Neck Radiotherapy with or without Chemotherapy (Alliance A221304) Miller, Robert C. , Le-Rademacher, Jennifer , Sio, Terence ... - ASTRO - Int. J. Radiat. Oncol. Biol. Phys. - 2016 Abstract - Primary Endpoint - Primary Analysis - Symptom Inter - A221304
N08C9 (Alliance): A Phase 3 Randomized Study of Sulfasalazine vs Placebo in the Prevention of Acute Diarrhea in Patients Receiving Pelvic Radiation Therapy Miller, Robert C. , Petereit, Daniel G. , Sloan, Jeff A. ... - - Int. J. Radiat. Oncol. Biol. Phys. - 2016 Manuscript - Primary Endpoint - Primary Analysis - Symptom Inter - N08C9
Randomized phase II study of loratadine for the prevention of bone pain caused by pegfilgrastim Moukharskaya, J. , Abrams, D.M. , Ashikaga, T. , Khan, F. ... - - Support Care Cancer - 2016 Manuscript - Primary Endpoint - Primary Analysis - Symptom Inter - NCT01311336
Olanzapine for the Prevention of Chemotherapy-Induced Nausea and Vomiting Navari, Rudolph M. , Qin, Rui , Ruddy, Kathryn J. , Liu, Heshan ... - - N. Engl. J. Med. - 2016 Manuscript - Primary Endpoint - Primary Analysis - Symptom Inter - A221301
Chromosome abnormalities at onset of complete remission are associated with worse outcome in patients with acute myeloid leukemia and an abnormal karyotype at diagnosis: CALGB 8461 (Alliance) Niederwieser, Christian , Nicolet, Deedra , Carroll, Andrew J. ... - - Haematologica - 2016 Manuscript - Secondary-not-in-original Endpoint - Comprehensive Analysis - Leuk Corr Sci - CALGB-10201 , CALGB-10502 , CALGB-10503 , CALGB-10603 , CALGB-10801 , CALGB-11002 , CALGB-19808 , CALGB-8461 , CALGB-8525 , CALGB-8923 , CALGB-9022 , CALGB-9621 , CALGB-9720
Association Between Results of a Gene Expression Signature Assay and Recurrence-Free Interval in Patients With Stage II Colon Cancer in Cancer and Leukemia Group B 9581 (Alliance) Niedzwiecki, Donna , Frankel, Wendy L. , Venook, Alan P. , Ye, Xing ... - - J. Clin. Oncol - 2016 Manuscript - Secondary Endpoint - Primary Analysis - Correl Sci NOS - C9581 , CALGB-150705
Blood-based biomarkers (BMs) in patients (pts) with metastatic colorectal cancer (mCRC) treated with FOLFOX or FOLFIRI + bevacizumab (Bev), cetuximab (Cetux) or Bev + Cetux: Results from CALGB 80405 Nixon, Andrew B. , Sibley, Alexander B. , Hatch, Ace J. ... - ASCO - J. Clin. Oncol. - 2016 Abstract - Secondary-not-in-original Endpoint - Primary Analysis - Correl Sci NOS - CALGB-80405
Survival implications of variation in the thoroughness of pathologic lymph node examination in American College of Surgeons Oncology Group Z0030 (Alliance) Osarogiagbon, Raymond U. , Decker, Paul A. , Ballman, Karla ... - - Ann. Thorac. Surg. - 2016 Manuscript - Secondary-not-in-original Endpoint - Primary Analysis - Respiratory - ACOSOG-Z0030
Comparison of oxaliplatin and paclitaxel-induced neuropathy (Alliance A151505) Pachman, Deirdre R. , Qin, Rui , Seisler, Drew ... - - Support Care Cancer - 2016 Manuscript - Primary Endpoint - Primary Analysis - Symptom Inter - A151505 , N08C1 , N08CB
Long non-coding RNA profiling provides important prognostic information and biologic insights in younger patients (pts) with cytogenetically normal acute myeloid leukemia (CN-AML) (Alliance) CALGB 8461, 9665, and 20202. Papaioannou, Dimitrios , Nicoleta, Deedra , Volinia, Stefano ... - EHA - - 2016 Abstract - Secondary Endpoint - Comprehensive Analysis - Leuk Corr Sci - CALGB-20202 , CALGB-8461 , CALGB-9665
A discovery study to identify clinical and genetic risk factors for bevacizumab (BEV)-related gastrointestinal (GI) hemorrhage (HEM) in metastatic castration-resistant prostate cancer (mCRPC) patients (pts) treated on CALGB 90401 (Alliance) Patel, Jai N. , Jiang, Chen , Owzar, Kouros , Hertz, Daniel L. ... - AACR - Cancer Res. - 2016 Abstract - Secondary-not-in-original Endpoint - Primary Analysis - PPP - CALGB-90401
Intrinsic Subtype and Therapeutic Response Among HER2-Positive Breast Tumors from the NCCTG (Alliance) N9831 Trial Perez, Edith A. , Ballman, Karla V. , Mashadi-Hossein, Afshin ... - - J. Natl. Cancer Inst - 2016 Manuscript - Secondary Endpoint - Primary Analysis - Breast - N9831
Intrinsic subtype and therapeutic response among early stage HER2-positive breast tumors from the North Central Cancer Treatment Group (Alliance) N9831 trial Perez, Edith A. , Ballman, Karla V. , Mashadi-Hossein, Afshin ... - SABCS - Cancer Res. - 2016 Abstract - Secondary Endpoint - Primary Analysis - Breast - N9831
Association of Stromal Tumor-Infiltrating Lymphocytes With Recurrence-Free Survival in the N9831 Adjuvant Trial in Patients With Early-Stage HER2-Positive Breast Cancer Perez, Edith A. , Ballman, Karla V. , Tenner, Kathy S. ... - - JAMA Oncol - 2016 Manuscript - Secondary Endpoint - Primary Analysis - Breast - N9831
Tobacco Assessment in Completed Lung Cancer Treatment Trials Peters, Erica N. , Warren, Graham W. , Sloan, Jeff A. ... - - Cancer - 2016 Manuscript - No-Endpoint Endpoint - Comprehensive Analysis - Prevention - Comprehensive
Adjuvant ovarian function suppression and cognitive function in women with breast cancer Phillips, Kelly-Anne , Regan, Meredith M , Ribi, Karin ... - - Br. J. Cancer - 2016 Manuscript - Secondary Endpoint - Primary Analysis - Breast - IBCSG-24-02 (SOFT-TEXT)
Alcohol consumption and colon cancer prognosis among participants in North Central Cancer Treatment Group phase III trial N0147 Phipps, Amanda I. , Shi, Qian , Limburg, Paul J. , Nelson, Garth D. ... - - Int. J. Cancer - 2016 Manuscript - Secondary Endpoint - Primary Analysis - GI - N0147
Adjuvant Lapatinib and Trastuzumab for Early Human Epidermal Growth Factor Receptor 2–Positive Breast Cancer: Results From the Randomized Phase III Adjuvant Lapatinib and/or Trastuzumab Treatment Optimization Trial Piccart-Gebhart, Martine , Holmes, Eileen , Baselga, José ... - - J. Clin. Oncol - 2016 Manuscript - Primary Endpoint - Primary Analysis - Breast - N063D
Absolute Benefit of Adjuvant Endocrine Therapies for Premenopausal Women With Hormone Receptor–Positive, Human Epidermal Growth Factor Receptor 2–Negative Early Breast Cancer: TEXT and SOFT Trials Regan, Meredith M. , Francis, Prudence A. , Pagani, Olivia ... - - J. Clin. Oncol - 2016 Manuscript - Secondary Endpoint - Primary Analysis - Breast - IBCSG-24-02 (SOFT-TEXT)
Findings from the Adjuvant Colon Cancer End Points (ACCENT) Collaborative Group: the power of pooled individual patient data from multiple clinical trials. Renfro, Lindsay A ... - - Chin Clin Oncol - 2016 Manuscript - Secondary-not-in-original Endpoint - Primary Analysis - GI - N0441
Adjuvant Tamoxifen Plus Ovarian Function Suppression Versus Tamoxifen Alone in Premenopausal Women With Early Breast Cancer: Patient-Reported Outcomes in the Suppression of Ovarian Function Trial Ribi, Karin , Luo, Weixiu , Bernhard, Jürg , Francis, Prudence A. ... - - J. Clin. Oncol - 2016 Manuscript - Primary Endpoint - Primary Analysis - Breast - IBCSG-24-02 (SOFT-TEXT)
Results of NCCTG N0275 (Alliance) – a phase II trial evaluating resection followed by adjuvant radiation therapy for patients with desmoplastic melanoma Rule, William G. , Allred, Jacob B. , Pockaj, Barbara A. ... - - Cancer Med - 2016 Manuscript - Primary Endpoint - Primary Analysis - Experimental - NCCTG-N0275
Positive Interaction Between Prophylactic Cranial Irradiation And Maintenance Sunitinib For Untreated Extensive Stage Small Cell Lung Cancer Patients After Standard Chemotherapy: A Secondary Analysis Of CALGB 30504 (Alliance) Salama, Joseph K. , Gu, Lin , Wang, Xiaofei , Pang, Herbert H. ... - - J Thorac Oncol - 2016 Manuscript - Secondary-not-in-original Endpoint - Primary Analysis - Respiratory - CALGB-30504
Event-free and overall survival following neoadjuvant weekly paclitaxel and dose-dense AC +/- carboplatin and/or bevacizumab in triple-negative breast cancer: outcomes from CALGB 40603 (Alliance) Sikov, William M , Berry, Donald A , Perou, Charles M , Singh, Baljit ... - SABCS - Cancer Res. - 2016 Abstract - Secondary Endpoint - Primary Analysis - Breast - CALGB-40603
A Phase II Trial Exploring the Success of Cryoablation Therapy in the Treatment of Invasive Breast Carcinoma: Results from ACOSOG (Alliance) Z1072 Simmons, Rache M. , Ballman, Karla V. , Cox, Charles , Carp, Ned ... - - Ann. Surg. Oncol. - 2016 Manuscript - Primary Endpoint - Primary Analysis - Breast - ACOSOG-Z1072
Relationship Between Metformin Use and Recurrence and Survival in Patients With Resected Stage III Colon Cancer Receiving Adjuvant Chemotherapy: Results From North Central Cancer Treatment Group N0147 (Alliance) Singh, Preet Paul , Shi, Qian , Foster, Nathan R. , Grothey, Axel ... - - Oncologist - 2016 Manuscript - Secondary-not-in-original Endpoint - Primary Analysis - GI - NCCTG-N0147
Molecular markers and survival after recurrence in stage III colon cancers from NCCTG N0147 and NSABP C-08 adjuvant chemotherapy trials Sinicrope, Frank A. , Shi, Qian , Allegra, Carmen Joseph ... - ASCO - J. Clin. Oncol. - 2016 Abstract - Secondary-not-in-original Endpoint - Primary Analysis - GI - N0147 , NCCTG-N0147
Association Of Tumor Infiltrating Lymphocytes (Tils) With Molecular Subtype And Prognosis In Stage III Colon Cancers From A FOLFOX-Based Adjuvant Chemotherapy Trial: NCCTG N0147 (Alliance) Sinicrope, Frank A. , Smyrk, Thomas C. , Foster, Nathan R. ... - ASCO - J. Clin. Oncol. - 2016 Abstract - Secondary Endpoint - Primary Analysis - GI - NCCTG-N0147
Repeated Measures Analyses of Dermatitis Symptom Evolution in Breast Cancer Patients Receiving Radiotherapy in a Phase 3 Randomized Trial of Mometasone Furoate vs Placebo (N06C4 [Alliance]) Sio, Terence T. , Atherton, Pamela J. , Birckhead, Brandon J ... - - Support Care Cancer - 2016 Manuscript - Secondary Endpoint - Primary Analysis - Symptom Inter - N06C4
Lessons from Large Scale Collection of Patient Reported Outcomes: Implications for Big Data Aggregation and Analytics Sloan, Jeff A. , Halyard, Michele , El Naqa, Issam ... - - Int. J. Radiat. Oncol. Biol. Phys. - 2016 Manuscript - No-Endpoint Endpoint - Other Analysis - Health Outcome - N9741 , NCCTG-89-20-52
The reliability, validity, and sensitivity of the European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire-chemotherapy-induced Peripheral Neuropathy (QLQ-CIPN-20). Smith, E. M. L. , Yang , J. , Banerjee, T. , Loprinizi, C. ... - MNRS - - 2016 Abstract - Secondary Endpoint - Primary Analysis - Symptom Inter - N06CA , CI-PeriNomS , N08C1 , N08CA , N08CB
Prognostic Value of BRAF and KRAS Mutations in MSI and MSS Stage III Colon Cancer Taieb, Julien , Le Malicot, Karine , Shi, Qian ... - - J. Natl. Cancer Inst - 2016 Manuscript - Secondary-not-in-original Endpoint - Primary Analysis - GI - N0147
Toxicities and related outcomes of elderly patients (≥65 years) with hematologic malignancies in the contemporary era (Alliance A151611) Tallarico, Michael , Foster, Jared , Seisler, Drew ... - ASH - Blood - 2016 Abstract - Primary Endpoint - Comprehensive Analysis - Older Adult - CALGB-10101 , A151611 , CALGB-10404 , CALGB-10501 , CALGB-19805 , CALGB-19901 , CALGB-50002 , CALGB-50103 , CALGB-50201 , CALGB-50401 , CALGB-50402 , CALGB-50501 , CALGB-50602 , CALGB-50701 , CALGB-50803
QOL and Survival Comparisons by Race in Oncology Clinical Trials Tan, AD , Novotny, PJ , Kaur, JS , Buckner, JC , Mowat, RB , Paskett, E ... - - J Cancer Clin Oncol - 2016 Manuscript - Secondary Endpoint - Comprehensive Analysis - Disparities - N0621 , N0691
Phase I study of panobinostat (LBH589) and letrozole in post-menopausal metastatic breast cancer patients Tan, Winston W. , Allred, Jacob B. , Moreno-Aspitia, Alvaro ... - - Clin. Breast Cancer - 2016 Manuscript - Primary Endpoint - Primary Analysis - Breast - NCCTG-N093B
A phase I/randomized phase II study of MLN0128 vs. Pazopanib in patients with locally advanced/unresectable and/or metastatic sarcoma: Alliance A091304 Tap, William , Mahoney, Michelle , Horvath, Elise ... - ASCO - J. Clin. Oncol. - 2016 Abstract - No-Endpoint Endpoint - Trial-Description-Only Analysis - Experimental - A091304
A novel approach of longitudinal adverse event evaluation in oncology clinical trials: the Toxicity over Time (ToxT) analysis of clinical trials N9741 and 979254 (Alliance) Thanarajasingam, Gita , Atherton, Pamela J. , Novotny, Paul J. ... - - Lancet Oncol. - 2016 Manuscript - Primary Endpoint - Comprehensive Analysis - Health Outcome - N9741 , NCCTG-97-92-54
Phase 1 trial of rituximab, lenalidomide, and ibrutinib in previously untreated follicular lymphoma: Alliance A051103 Ujjani, Chaitra S. , Jung, Sin-Ho , Pitcher, Brandelyn ... - - Blood - 2016 Manuscript - Primary Endpoint - Primary Analysis - Lymphoma - A051103
Impact of primary (1º) tumor location on overall survival (OS) in patients (pts) with metastatic colorectal cancer (mCRC): Analysis of CALGB / SWOG 80405 (Alliance) Venook, Alan P. , Niedzwiecki, Donna , Innocenti, Federico ... - ASCO - J. Clin. Oncol. - 2016 Abstract - Secondary Endpoint - Primary Analysis - GI - CALGB-80405
Impact of Race, Ethnicity and BMI on Achievement of Pathologic Complete Response Following Neoadjuvant Chemotherapy for Breast Cancer: A Pooled Analysis of Four Prospective Alliance Clinical Trials (A151426) Warner, Erica T. , Ballman, Karla V. , Strand, Carrie , Boughey, Judy ... - - Breast Cancer Res. Treat. - 2016 Manuscript - Primary Endpoint - Comprehensive Analysis - Disparities - A151426 , ACOSOG-Z1041 , ACOSOG-Z1071 , CALGB-40601 , CALGB-40603
A phase II study of dasatinib and dexamethasone as primary therapy followed by hematopoietic cell transplantation for adults with Philadelphia chromosome-positive acute lymphoblastic leukemia: CALGB Study 10701 (Alliance) Wieduwilt, Matthew J. , Yin, Jun , Wetzler, Meir , Uy, Geoff ... - ASH - Blood - 2016 Abstract - Secondary Endpoint - Primary Analysis - Leukemia - CALGB-10701
Phase III randomized study of R-CHOP versus DA-EPOCH-R and molecular analysis of untreated diffuse large B-cell lymphoma: Alliance/CALGB 50303 Wilson, Wyndham H. , Jung, Sin-Ho , Pitcher, Brandelyn , Hsi, Eric ... - ASH - Blood - 2016 Abstract - Primary Endpoint - Primary Analysis - Lymphoma - CALGB-50303
Deletions in HSP110 T17 and Patient Prognosis in Stage III Microsatellite Instable (MSI) Colon Cancers: Findings from CALGB 89803 and NCCTG N0147. Wu, Christina , Shi, Qian , Tomsic, Jerneja , Meyers, Jeffrey ... - ASCO - J. Clin. Oncol. - 2016 Abstract - Secondary-not-in-original Endpoint - Primary Analysis - GI - CALGB-89803 , NCCTG-N0147
Impact of the Timing of Complete Remission and Transplantation on Estimates of Event-Free Survival in Acute Myeloid Leukemia Yin, Jun , Laplant, Betsy R. , Uy, Geoffrey L. , Marcucci, Guido ... - ASH - JAMA Oncol - 2016 Abstract - Primary Endpoint - Comprehensive Analysis - Leukemia - CALGB-10201 , A151614 , CALGB-10503 , CALGB-10603 , CALGB-10801 , CALGB-11001
Gene expression profiling identifies responsive patients with cancer of unknown primary treated with carboplatin, paclitaxel, and everolimus: NCCTG N0871 (Alliance) Yoon, H. H. , Foster, N. R. , Meyers, J. P. , Steen, P. D. ... - - Ann. Oncol - 2016 Manuscript - Primary Endpoint - Primary Analysis - Experimental - NCCTG-N0871
MC11C4: a pilot randomized, placebo-controlled, double-blind study of venlafaxine to prevent oxaliplatin-induced neuropathy Zimmerman, Collin , Atherton, Pamela J. , Pachman, Deirdre ... - - Support Care Cancer - 2016 Manuscript - Primary Endpoint - Primary Analysis - Symptom Inter - NCT01611155
