Increased Expression of Macrophage Migration Inhibitory Factor (MIF) Receptor CD74 Is Associated with Inferior Outcome in Younger Patients (Pts) with Cytogenetically Normal Acute Myeloid Leukemia (CN-AML): a Cancer and Leukemia Group B (CALGB) Study Attar, E. C. , Maharry, K. , Mrozek, K. , Radmacher, M. D. ... - ASH - Blood - 2009 Abstract - Secondary - Primary - Leuk Corr Sci - CALGB-10502 , CALGB-20202 , CALGB-20502 , CALGB-8461
Cytarabine, daunorubicin and etoposide (ADE) chemotherapy in acute myeloid leukemia (AML) patients >= 60 years (CALGB 9720) Baer, M. R. , George, S. L. , Sanford, B. L. , Bothun, S. M. ... - - Blood - 2007 Abstract - Secondary - Primary - Leukemia - CALGB-8461 , CALGB-9720
Low-Dose Interleukin-2 Immunotherapy Does Not Improve Outcome of Patients Age 60 Years and Older With Acute Myeloid Leukemia in First Complete Remission: Cancer and Leukemia Group B Study 9720 Baer, Maria R. , George, Stephen L. , Caligiuri, Michael A. ... - - J Clin Oncol - 2008 Manuscript - Secondary - Primary - Leukemia - CALGB-8461 , CALGB-9720
Sole Trisomy 8 In Patients (pts) with De Novo Acute Myeloid Leukemia (AML) Is Associated with Age-Independent Poor Outcome That Is Modified by Molecular Markers and with Unique Gene- and Microrna (miR)-Signatures: a Cancer and Leukemia Group B (CALGB) Study Becker, H. , Maharry, K. , Radmacher, M. D. , Margeson, D. ... - - Blood - 2010 Abstract - Secondary - Primary - Leuk Corr Sci - C8525 , CALGB-10201 , CALGB-19808 , CALGB-20202 , CALGB-20502 , CALGB-8461 , CALGB-8923 , CALGB-9420 , CALGB-9621 , CALGB-9665 , CALGB-9720
NPM1 mutations as an independent prognosticator for older cytogenetically normal acute myeloid leukemia (CN AML) Becker, H. , Marcucci, G. , Maharry, K. , Margeson, D. ... - - J. Clin. Oncol. - 2009 Abstract - Secondary - Primary - Leuk Corr Sci - CALGB-10201 , CALGB-20202 , CALGB-8461 , CALGB-9720
Comparison of Clinical and Biologic Significance of WT1 Mutations in Populations of Older (>= 60 years y ) and Younger (< 60 y) Adult Patients (Pts) with Cytogenetically Normal (CN) De Novo Acute Myeloid Leukemia (AML): a Cancer and Leukemia Group B (CALGB) Study Becker, H. , Marcucci, G. , Maharry, K. , Radmacher, M. D. ... - - Blood - 2009 Abstract - Secondary-not-in-original - Primary - Correl Sci NOS - C8525 , CALGB-10201 , CALGB-19808 , CALGB-20202 , CALGB-20502 , CALGB-8461 , CALGB-8923 , CALGB-9420 , CALGB-9621 , CALGB-9665 , CALGB-9720
CEBPA double mutations impact favorably on the outcome of older adults with wild-type NPM1 cytogenetically normal acute myeloid leukemia and are associated with distinct gene- and microRNA-expression patterns Becker, H. , Marcucci, G. , Maharry, K. , Radmacher, M. , Wu, Y. ... - - Haematologica - 2010 Abstract - Secondary - Primary - Leuk Corr Sci - C8525 , CALGB-10201 , CALGB-20202 , CALGB-20502 , CALGB-8461 , CALGB-8923 , CALGB-9420 , CALGB-9665 , CALGB-9720
Clinical outcome and gene- and microRNA-expression profiling according to the Wilms tumor 1 (WT1) single nucleotide polymorphism rs16754 in adult de novo cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study Becker, Heiko , Maharry, Kati , Radmacher, Michael D. ... - - Haematologica - 2011 Manuscript - Secondary - Primary - Leuk Corr Sci - C8525 , CALGB-10201 , CALGB-19808 , CALGB-20202 , CALGB-20502 , CALGB-8461 , CALGB-8923 , CALGB-9420 , CALGB-9621 , CALGB-9665 , CALGB-9720
Mutations of the Wilms tumor 1 gene (WT1) in older patients with primary cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study Becker, Heiko , Marcucci, Guido , Maharry, Kati ... - - Blood - 2010 Manuscript - Secondary - Primary - Leuk Corr Sci - C8525 , CALGB-10201 , CALGB-19808 , CALGB-20202 , CALGB-8461 , CALGB-8923 , CALGB-9420 , CALGB-9621 , CALGB-9665 , CALGB-9720
Favorable Prognostic Impact of NPM1 Mutations in Older Patients With Cytogenetically Normal De Novo Acute Myeloid Leukemia and Associated Gene- and MicroRNA-Expression Signatures: A Cancer and Leukemia Group B Study Becker, Heiko , Marcucci, Guido , Maharry, Kati ... - - J Clin Oncol - 2010 Manuscript - Secondary - Primary - Leuk Corr Sci - CALGB-10201 , CALGB-19808 , CALGB-20202 , CALGB-8461 , CALGB-9720
Acute myeloid leukemia (AML) patients with an isolated trisomy display increased frequency of spliceosome mutations CALGB 8461 and 20202 (Alliance) Bhatnagar, Bhavana , Eisfeld, Ann-Kathrin , Mrózek, Krzysztof ... - ASH - Blood - 2017 Abstract - Secondary-not-in-original - Primary - Leuk Corr Sci - CALGB-20202 , CALGB-8461
Poor Survival and Differential Impact of Genetic Features of Black Patients with Acute Myeloid Leukemia. Bhatnagar, Bhavana , Kohlschmidt, Jessica , Mrózek, Krzysztof ... - - Cancer Discov - 2020 Manuscript - Secondary-not-in-original - Primary - Leuk Corr Sci - CALGB-20202 , CALGB-8461 , CALGB-9665
Mutational Landscape and Clinical Outcome Associated with Different Rearrangements Involving 11q23/MLL in De Novo Acute Myeloid Leukemia (AML) CALB 8461 and 20202 (Alliance) Bill, Marius , Eisfeld, Ann-Kathrin , Mrózek, Krzysztof ... - ASH - Blood - 2017 Abstract - Secondary-not-in-original - Primary - Leuk Corr Sci - CALGB-20202 , CALGB-8461
Differential Impact of Prognostically Significant Gene Mutations in Acute Myeloid Leukemia (AML) Patients (Pts) Older Than 70 Years (y) Treated With a Cytarabine-Based Induction Therapy (Alliance) Bill, Marius , Kohlschmidt, Jessica , Mrózek, Krzysztof ... - ASH - Blood - 2020 Abstract - Secondary-not-in-original - Primary - Leuk Corr Sci - CALGB-20202 , CALGB-8461 , CALGB-9665
Mutational landscape and clinical outcome of patients with de novo acute myeloid leukemia and rearrangements involving 11q23/KMT2A Bill, Marius , Mrózek, Krzysztof , Kohlschmidt, Jessica ... - - Proc Natl Acad Sci U S A - 2020 Manuscript - Secondary-not-in-original - Primary - Leuk Corr Sci - CALGB-20202 , CALGB-8461 , CALGB-9665
Validation of the prognostic significance of the knowledge bank (KB) algorithm in adult acute myeloid leukemia (AML) patients (pts) treated on Cancer and Leukemia Group B (CALGB)/Alliance protocols and suggestions for improvements Bill, Marius , Mrózek, Krzysztof , Kohlschmidt, Jessica ... - EHA - - 2020 Abstract - Secondary-not-in-original - Primary - Leuk Corr Sci - CALGB-20202 , CALGB-8461 , CALGB-9665
Personalized Oncology in Acute Myeloid Leukemia (AML): Validation of the Prognostic Value of the Knowledge Bank Approach in Patients (Pts) Treated on Cancer and Leukemia Group B/Alliance Protocols Bill, Marius , Mrózek, Krzysztof , Kohlschmidt, Jessica ... - ASH - Blood - 2019 Abstract - Secondary-not-in-original - Primary - Leukemia - CALGB-20202 , CALGB-8461 , CALGB-9665
A 17-gene leukemia stem cell (LSC) score in adult patients (pts) with acute myeloid leukemia (AML) reveals a distinct mutational landscape and refines current European Leukemianet (ELN) genetic risk stratification (Alliance) Bill, Marius , Nicolet, Deedra , Eisfeld, Ann-Kathrin ... - ASH - Blood - 2018 Abstract - Secondary-not-in-original - Primary - Leuk Corr Sci - CALGB-20202 , CALGB-8461
Mutations associated with a 17-gene leukemia stem cell score and the score’s prognostic relevance in the context of the European LeukemiaNet classification of acute myeloid leukemia Bill, Marius , Nicolet, Deedra , Kohlschmidt, Jessica ... - - Haematologica - 2020 Manuscript - Secondary-not-in-original - Primary - Leuk Corr Sci - C8621 , CALGB-8461 , C8721 , CALGB-10201 , CALGB-10502 , CALGB-10503 , CALGB-10603 , CALGB-11001 , CALGB-11002 , CALGB-19808 , CALGB-20202 , CALGB-8525 , CALGB-8821 , CALGB-8923 , CALGB-9022 , CALGB-9120 , CALGB-9222 , CALGB-9420 , CALGB-9621 , CALGB-9665 , CALGB-9720
Acute Myeloid Leukemia (AML) with 9q aberrations occuring within a non-complex karyotype is highly associated with CEBPA and NPM1 mutations - A joint analysis of the German-Austrian AML Study Group (AMLSG) and Cancer and Leukemia Group B (CALGB) Corbacioglu, A. , Frohling, S. , Paschka, P. , Marcucci, G. ... - ASH - Blood - 2007 Abstract - Secondary-not-in-original - Primary - Leuk Corr Sci - CALGB-19808 , CALGB-8461 , CALGB-9621 , CALGB-9665
The mutational oncoprint of recurrent cytogenetic abnormalities in adult patients with de novo acute myeloid leukemia Eisfeld, A-K , Mrózek, K , Kohlschmidt, J , Nicolet, D , Orwick, S ... - - Leukemia - 2017 Manuscript - Secondary-not-in-original - Meta-Analysis - Leuk Corr Sci - CALGB-20202 , CALGB-8461 , CALGB-9665
Adult acute myeloid leukemia with trisomy 11 as the sole abnormality is characterized by the presence of five distinct gene mutations: MLL-PTD, DNMT3A, U2AF1, FLT3-ITD and IDH2 Eisfeld, Ann-Kathrin , Kohlschmidt, Jessica , Mrózek, Krzysztof ... - - Leukemia - 2016 Manuscript - Secondary - Primary - Leuk Corr Sci - CALGB-20202 , CALGB-8461
Mutation patterns identify adult patients with de novo acute myeloid leukemia aged 60 years or older who respond favorably to standard chemotherapy: an analysis of Alliance studies Eisfeld, Ann-Kathrin , Kohlschmidt, Jessica , Mrózek, Krzysztof ... - - Leukemia - 2018 Manuscript - Secondary-not-in-original - Meta-Analysis - Leuk Corr Sci - C8461 , C8525 , C8821 , C9665 , CALGB-10201 , CALGB-10502 , CALGB-11001 , CALGB-11002 , CALGB-20202 , CALGB-8461 , CALGB-8923 , CALGB-9420 , CALGB-9720
The 2017 European LeukemiaNet Genetic Risk Classification performs poorly in elderly Acute Myeloid Leukemia (AML) patients and should be refined to enable identification of patients requiring additional or alternative treatment (Alliance) Eisfeld, Ann-Kathrin , Kohlschmidt, Jessica , Mrózek, Krzysztof ... - ASH - Blood - 2019 Abstract - Secondary-not-in-original - Primary - Leukemia - CALGB-20202 , CALGB-8461 , CALGB-9665
Mutational landscape and gene-expression patterns in adult acute myeloid leukemias with monosomy 7 as a sole abnormality Eisfeld, Ann-Kathrin , Kohlschmidt, Jessica , Mrózek, Krzysztof ... - - Cancer Res. - 2017 Manuscript - Secondary-not-in-original - Meta-Analysis - Leuk Corr Sci - CALGB-10201 , CALGB-10503 , CALGB-10603 , CALGB-11002 , CALGB-19808 , CALGB-20202 , CALGB-8461 , CALGB-8525 , CALGB-9222 , CALGB-9420 , CALGB-9621
Mutations in the CCND1 and CCND2 genes are frequent events in adult patients with t(8;21)(q22;q22) acute myeloid leukemia Eisfeld, Ann-Kathrin , Kohlschmidt, Jessica , Schwind, Sebastian ... - - Leukemia - 2017 Manuscript - Secondary - Primary - Leuk Corr Sci - CALGB-20202 , CALGB-8461 , CALGB-9665
Dual Epigenetic Control of CCAAT/Enhancer Binding Protein {alpha} (C/EBP{alpha}) Expression in Acute Myeloid Leukemia Hackanson, B. , Bennett, K. L. , Brena, R. M. , Jiang, J. ... - - Blood - 2007 Abstract - Secondary - Primary - Leuk Corr Sci - CALGB-19808 , CALGB-20502 , CALGB-8461 , CALGB-9621 , CALGB-9665
Epigenetic modification of CCAAT/enhancer binding protein alpha expression in acute myeloid leukemia. Hackanson, Björn , Bennett, Kristi L , Brena, Romulo M ... - - Cancer Res. - 2008 Manuscript - Secondary - Primary - Leuk Corr Sci - CALGB-8461 , CALGB-9665
Phase III Trial of Immunotherapy with Recombinant Interleukin-2 (rIL-2) Versus Observation in Patients < 60 Years with Acute Myeloid Leukemia (AML) in First Remission (CR1): Preliminary Results from Cancer and Leukemia Group B (CALGB) 19808 Kolitz, J. E. , Hars, V. , Deangelo, D. J. , Allen, S. L. ... - - Blood - 2007 Abstract - Primary - Preliminary - Leukemia - CALGB-19808 , CALGB-8461 , CALGB-9665
P-glycoprotein inhibition using valspodar (PSC-833) does not improve outcomes for patients younger than age 60 years with newly diagnosed acute myeloid leukemia: Cancer and Leukemia Group B study 19808 Kolitz, Jonathan E. , George, Stephen L. , Marcucci, Guido ... - - Blood - 2010 Manuscript - Primary - Primary - Leukemia - CALGB-19808 , CALGB-8461
High BAALC expression associates with other molecular prognostic markers, poor outcome and a distinct gene expression signature in cytogenetically normal acute myeloid leukemia (CN AML): A Cancer and Leukemia Group B (CALGB) study Langer, C. , Ruppert, A. S. , Radmacher, M. D. , Whitman, S. P. ... - - J. Clin. Oncol. - 2007 Abstract - Secondary - Primary - Leuk Corr Sci - CALGB-19808 , CALGB-20502 , CALGB-8461 , CALGB-9621 , CALGB-9665
Prognostic Importance of MN1 Transcript Levels, and Biologic Insights From MN1-Associated Gene and MicroRNA Expression Signatures in Cytogenetically Normal Acute Myeloid Leukemia: A Cancer and Leukemia Group B Study Langer, Christian , Marcucci, Guido , Holland, Kelsi B. ... - - J Clin Oncol - 2009 Manuscript - Secondary - Primary - Leuk Corr Sci - CALGB-19808 , CALGB-20502 , CALGB-8461 , CALGB-9621 , CALGB-9665
High BAALC expression associates with other molecular prognostic markers, poor outcome, and a distinct gene-expression signature in cytogenetically normal patients younger than 60 years with acute myeloid leukemia: a Cancer and Leukemia Group B (CALGB) study Langer, Christian , Radmacher, Michael D. , Ruppert, Amy S. ... - - Blood - 2008 Manuscript - Secondary - Primary - Leuk Corr Sci - CALGB-19808 , CALGB-20502 , CALGB-8461 , CALGB-9621 , CALGB-9665
What Determines the Outcome for Adolescents and Young Adults With Acute Lymphoblastic Leukemia? Larson, R. A. ... - - Ann Hematol - 2008 Abstract - Secondary-not-in-original - Primary - Leukemia - C8811 , C9331 , CALGB-19802 , CALGB-8461
Distinct patterns of mutations occurring in de novo AML versus AML arising in the setting of severe congenital neutropenia Link, Daniel C. , Kunter, Ghada , Kasai, Yumi , Zhao, Yu ... - - Blood - 2007 Manuscript - Secondary - Primary - Leuk Corr Sci - CALGB-8461 , CALGB-9665
Chromosome 5q deletion and epigenetic suppression of the gene encoding alpha-catenin (CTNNA1) in myeloid cell transformation. Liu, Ting Xi , Becker, Michael W , Jelinek, Jaroslav , Wu, Wen-Shu ... - - Nat. Med. - 2007 Manuscript - Secondary - Primary - Leuk Corr Sci - CALGB-8461 , CALGB-9665
Quantitative Measurement of CD52 Expression and Alemtuzumab Binding in Adult Acute Lymphoblastic Leukemia (ALL): Correlation with Immunophenotype and Cytogenetics in Patients (Pts) Enrolled on a Phase I/II Trial from the Cancer and Leukemia Group B (CALGB 10102) Lozanski, G. , Sanford, B. , Mrozek, K. , Edwards, C. , Pearson, R. ... - ASH - Blood - 2007 Abstract - Secondary - Primary - Leuk Corr Sci - CALGB-10102 , CALGB-8461 , CALGB-9665 , CALGB-9862
High ERG expression levels predict adverse outcome and refine molecular risk-based classification of cytogenetically normal (CN) acute myeloid leukemia (AML): A Cancer and Leukemia Group B (CALGB) study Marcucci, G. , Maharry, K. S. , Whitman, S. P. , Vukosavljevic, T. ... - AACR - AACR Annual Meeting - 2007 Abstract - Secondary - Primary - Leuk Corr Sci - CALGB-19808 , CALGB-20502 , CALGB-8461 , CALGB-9621 , CALGB-9665
IDH1 and IDH2 gene mutations identify novel molecular subsets within de novo cytogenetically normal acute myeloid leukemia (CN-AML): A Cancer and Leukemia Group B (CALGB) Study Marcucci, G. , Maharry, K. S. , Wu, Y. , Radmacher, M. D. ... - - Haematologica - 2010 Abstract - Secondary - Primary - Leuk Corr Sci - C8525 , CALGB-10201 , CALGB-19808 , CALGB-20202 , CALGB-20502 , CALGB-8461 , CALGB-8923 , CALGB-9420 , CALGB-9621 , CALGB-9665 , CALGB-9720
Gene and microRNA (miRNA) Expression Signatures and Prognostic Significance of CEBPA Mutations in Cytogenetically Normal (CN) Acute Myeloid Leukemia (AML) with High-Risk Molecular Features: A Cancer and Leukemia Group B (CALGB) Study Marcucci, G. , Maharry, K. , Radmacher, M. D. , Mrozek, K. ... - - Blood - 2007 Abstract - Secondary - Primary - Leuk Corr Sci - CALGB-19808 , CALGB-20205 , CALGB-20502 , CALGB-8461 , CALGB-9621 , CALGB-9665
Clinical Role of microRNAs in Cytogenetically Normal Acute Myeloid Leukemia: miR-155 Upregulation Independently Identifies High-Risk Patients Marcucci, Guido , Maharry, Kati S. , Metzeler, Klaus H. ... - - J. Clin. Oncol. - 2013 Manuscript - Secondary - Primary - Leuk Corr Sci - CALGB-8461 , CALGB-9665 , CALGB-20202
Prognostic Significance of, and Gene and MicroRNA Expression Signatures Associated With, CEBPA Mutations in Cytogenetically Normal Acute Myeloid Leukemia With High-Risk Molecular Features: A Cancer and Leukemia Group B Study Marcucci, Guido , Maharry, Kati , Radmacher, Michael D. ... - - J Clin Oncol - 2008 Manuscript - Secondary - Primary - Leuk Corr Sci - CALGB-19808 , CALGB-20502 , CALGB-8461 , CALGB-9621 , CALGB-9665
High expression levels of the ETS-related gene, ERG, predict adverse outcome and improve molecular risk-based classification of cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B Study. Marcucci, Guido , Maharry, Kati , Whitman, Susan P ... - - J. Clin. Oncol. - 2007 Manuscript - Secondary - Primary - Leuk Corr Sci - CALGB-19808 , CALGB-20205 , CALGB-20502 , CALGB-8461 , CALGB-9621 , CALGB-9665
MicroRNA expression in cytogenetically normal acute myeloid leukemia. Marcucci, Guido , Radmacher, Michael D , Maharry, Kati ... - - N. Engl. J. Med. - 2008 Manuscript - Secondary - Primary - Leuk Corr Sci - CALGB-19808 , CALGB-20502 , CALGB-8461 , CALGB-9621 , CALGB-9665
RUNX1 Mutations Are Associated With Poor Outcome in Younger and Older Patients With Cytogenetically Normal Acute Myeloid Leukemia and With Distinct Gene and MicroRNA Expression Signatures Mendler, Jason H. , Maharry, Kati , Radmacher, Michael D. ... - - J. Clin. Oncol. - 2012 Manuscript - Secondary - Primary - Leuk Corr Sci - C8525 , CALGB-8461 , CALGB-8923 , CALGB-9420 , CALGB-9621 , CALGB-9665 , CALGB-9720 , CALGB-10201 , CALGB-19808 , CALGB-20202
ASXL1 Mutations Identify a High-Risk Subgroup of Older Patients with Primary Cytogenetically Normal Acute Myeloid Leukemia within the European LeukemiaNet 'Favorable' Genetic Category Metzeler, K. H. , Becker, H. , Maharry, K. , Radmacher, M. D. ... - - Blood - 2011 Abstract - Secondary - Primary - Leuk Corr Sci - CALGB-20202 , CALGB-8461 , CALGB-9665
An 86-Probe Gene Expression Signature Can Predict Survival in AML with Normal Karyotype Independently of FLT3 ITD and NPM1 Mutation Status - A Collaborative Study from the AMLCG and CALGB Study Groups Metzeler, K. H. , Hummel, M. , Bloomfield, C. D. , Spiekermann, K. ... - - Blood - 2007 Abstract - Secondary - Primary - Leuk Corr Sci - CALGB-8461 , CALGB-9621 , CALGB-9665
TET2 mutations occur in over 20% of adults with de novo cytogenetically normal AML, and their prevalence increases with age: A Cancer and Leukemia Goup B study. Metzeler, K. H. , Maharry, K. , Margeson, D. , Curfman, J. ... - - Haematologica - 2010 Abstract - Secondary - Primary - Leuk Corr Sci - C8525 , CALGB-10201 , CALGB-19808 , CALGB-20202 , CALGB-20502 , CALGB-8461 , CALGB-8923 , CALGB-9420 , CALGB-9621 , CALGB-9665 , CALGB-9720
A stem cell-like gene expression signature associates with inferior outcomes and a distinct microRNA expression profile in adults with primary cytogenetically normal acute myeloid leukemia Metzeler, KH , Maharry, K , Kohlschmidt, J , Volinia, S , Mrózek, K ... - - Leukemia - 2013 Manuscript - Secondary - Primary - Leuk Corr Sci - CALGB-8461 , CALGB-9665 , CALGB-20202
ASXL1 mutations identify a high-risk subgroup of older patients with primary cytogenetically normal AML within the ELN Favorable genetic category Metzeler, Klaus H. , Becker, Heiko , Maharry, Kati ... - - Blood - 2011 Manuscript - Secondary - Primary - Leuk Corr Sci - CALGB-20202 , CALGB-8461 , CALGB-9665
An 86-probe-set gene-expression signature predicts survival in cytogenetically normal acute myeloid leukemia Metzeler, Klaus H. , Hummel, Manuela , Bloomfield, Clara D. ... - - Blood - 2008 Manuscript - Secondary-not-in-original - Meta-Analysis - Leuk Corr Sci - CALGB-8461 , CALGB-9621 , CALGB-9665
TET2 Mutations Improve the New European LeukemiaNet Risk Classification of Acute Myeloid Leukemia: A Cancer and Leukemia Group B Study Metzeler, Klaus H. , Maharry, Kati , Radmacher, Michael D. ... - - J Clin Oncol - 2011 Manuscript - Secondary - Primary - Leuk Corr Sci - C8525 , CALGB-10201 , CALGB-19808 , CALGB-20202 , CALGB-20502 , CALGB-8461 , CALGB-8923 , CALGB-9420 , CALGB-9621 , CALGB-9665 , CALGB-9720
Comparison of clinical and molecular characteristics of patients with acute myeloid leukemia and either TP73 or TP53 mutations. Mims, Alice S , Kohlschmidt, Jessica , Eisfeld, Ann-Kathrin ... - - Leukemia - 2020 Manuscript - Secondary-not-in-original - Primary - Leuk Corr Sci - CALGB-20202 , CALGB-8461 , CALGB-9665
Prognostic Utility of the European LeukemiaNet (ELN) Genetic-Risk Classification in Adults with De Novo Acute Myeloid Leukemia (AML): A Study of 1,550 Patients (Pts) Mrozek, K. , Marcucci, G. , Maharry, K. , Nicolet, D. , Becker, H. ... - - Blood - 2011 Abstract - Secondary - Primary - Leuk Corr Sci - C8525 , CALGB-10201 , CALGB-19808 , CALGB-20202 , CALGB-8461 , CALGB-8923 , CALGB-9420 , CALGB-9621 , CALGB-9665 , CALGB-9720
Central review of cytogenetics is necessary for cooperative group correlative and clinical studies of adult acute leukemia: The Cancer and Leukemia Group B experience Mrózek, Krzysztof , Carroll, Andrew J. , Maharry, Kati ... - - Int. J. Oncol. - 2008 Manuscript - No-Endpoint - Comprehensive - Leuk Corr Sci - CALGB-8461
Molecular landscape and clinical features of acute myeloid leukemia (AML) with complex karyotype (CK) CALGB 20202 and 8461 (Alliance) Mrózek, Krzysztof , Eisfeld, Ann-Kathrin , Kohlschmidt, Jessica ... - ASH - Blood - 2017 Abstract - Secondary-not-in-original - Primary - Leuk Corr Sci - CALGB-20202 , CALGB-8461
Prognostic Significance of the European LeukemiaNet Standardized System for Reporting Cytogenetic and Molecular Alterations in Adults With Acute Myeloid Leukemia Mrózek, Krzysztof , Marcucci, Guido , Nicolet, Deedra ... - - J. Clin. Oncol. - 2012 Manuscript - Secondary - Primary - Leuk Corr Sci - CALGB-10201 , CALGB-19808 , CALGB-8461 , CALGB-8525 , CALGB-8923 , CALGB-9420 , CALGB-9621 , CALGB-9720
Patients With Acute Myeloid Leukemia and RAS Mutations Benefit Most From Postremission High-Dose Cytarabine: A Cancer and Leukemia Group B Study Neubauer, Andreas , Maharry, Kati , Mrózek, Krzysztof ... - - J Clin Oncol - 2008 Manuscript - Secondary - Primary - Leuk Corr Sci - C8525 , C8765 , CALGB-8461 , CALGB-9665
FTY720, a new and alternative strategy for treating blast crisis CML and Ph1 ALL patients Neviani, P. , Santhanam, R. , Oaks, J. , Eiring, A. , Notari, M. ... - AACR - AACR Annual Meeting - 2007 Abstract - Secondary-not-in-original - Primary - Leuk Corr Sci - CALGB-8461 , CALGB-9665
FTY720, a new alternative for treating blast crisis chronic myelogenous leukemia and Philadelphia chromosome–positive acute lymphocytic leukemia Neviani, Paolo , Santhanam, Ramasamy , Oaks, Joshua J. ... - - J Clin Invest - 2007 Manuscript - Secondary-not-in-original - Primary - Leuk Corr Sci - CALGB-8461 , CALGB-9665
Multivitamin Use Is Not Associated With Cancer Recurrence or Survival in Patients With Stage III Colon Cancer: Findings From CALGB 89803 Ng, Kimmie , Meyerhardt, Jeffrey A. , Chan, Jennifer A. ... - - J Clin Oncol - 2010 Manuscript - Secondary - Primary - GI - CALGB-8461 , CALGB-9665
Chromosome abnormalities at onset of complete remission are associated with worse outcome in patients with acute myeloid leukemia and an abnormal karyotype at diagnosis: CALGB 8461 (Alliance) Niederwieser, Christian , Nicolet, Deedra , Carroll, Andrew J. ... - - Haematologica - 2016 Manuscript - Secondary-not-in-original - Meta-Analysis - Leuk Corr Sci - CALGB-10201 , CALGB-10502 , CALGB-10503 , CALGB-10603 , CALGB-10801 , CALGB-11002 , CALGB-19808 , CALGB-8461 , CALGB-8525 , CALGB-8923 , CALGB-9022 , CALGB-9621 , CALGB-9720
Differential Clinical Impact Of Gene Mutations and Their Combinations In Primary Cytogenetically Normal Acute Myeloid Leukemia (CN-AML) Papaioannou, Dimitrios , Maharry, Kati , Mrózek, Krzysztof ... - ASH - Blood - 2013 Abstract - Secondary - Primary - Leuk Corr Sci - CALGB-20202 , CALGB-9665 , CALGB-8461
Next-Generation RNA Sequencing-Based Analysis Identifies a Novel Set of Prognostic MicroRNAs (miRs) in Cytogenetically Normal Acute Myeloid Leukemia (CN-AML) (Alliance) Papaioannou, Dimitrios , Nicolet, Deedra , Archer, Kellie J. ... - ASH - Blood - 2019 Abstract - Secondary-not-in-original - Primary - Leuk Corr Sci - CALGB-20202 , CALGB-8461 , CALGB-9665
Prognostic and biologic significance of long non-coding RNA profiling in younger adults with cytogenetically normal acute myeloid leukemia Papaioannou, Dimitrios , Nicolet, Deedra , Volinia, Stefano ... - - Haematologica - 2017 Manuscript - Secondary - Primary - Leuk Corr Sci - CALGB-10503 , CALGB-10603 , CALGB-19808 , CALGB-20202 , CALGB-8461 , CALGB-8525 , CALGB-9022 , CALGB-9222 , CALGB-9621 , CALGB-9665
Long non-coding RNA profiling provides important prognostic information and biologic insights in younger patients (pts) with cytogenetically normal acute myeloid leukemia (CN-AML) (Alliance) CALGB 8461, 9665, and 20202. Papaioannou, Dimitrios , Nicoleta, Deedra , Volinia, Stefano ... - EHA - - 2016 Abstract - Secondary - Meta-Analysis - Leuk Corr Sci - CALGB-20202 , CALGB-8461 , CALGB-9665
Recurrent Genetic Variants of Long Non-Coding RNAs Independently Associate with Clinical Outcome of Younger Adults with Cytogenetically Normal Acute Myeloid Leukemia (ALLIANCE/CALGB 8461, 9665, 20202) Papaioannou, Dimitrios , Ozer, Gulcin H. , Nicolet, Deedra ... - ASH - Blood - 2017 Abstract - Secondary-not-in-original - Primary - Leuk Corr Sci - CALGB-20202 , CALGB-8461 , CALGB-9665
Prognostic and biological significance of the proangiogenic factor EGFL7 in acute myeloid leukemia Papaioannou, Dimitrios , Shen, Changxian , Nicolet, Deedra ... - - Proc. Natl. Acad. Sci. U.S.A - 2017 Manuscript - Secondary - Primary - Leuk Corr Sci - CALGB-10201 , CALGB-10503 , CALGB-10603 , CALGB-19808 , CALGB-20202 , CALGB-8461 , CALGB-8525 , CALGB-8923 , CALGB-9022 , CALGB-9120 , CALGB-9222 , CALGB-9420 , CALGB-9665 , CALGB-9720
Prognostic and biologic significance of circular RNA profiling in younger adult patients with cytogenetically normal acute myeloid leukemia (CN-AML) (CALGB/Alliance 8461, 9665, 20202) Papaioannou, Dimitrios , Volinia, Stefano , Nicolet, Deedra ... - EHA - - 2018 Abstract - Secondary-not-in-original - Primary - Leuk Corr Sci - CALGB-20202 , CALGB-8461 , CALGB-9665
Prognostic impact of NPM1 mutations in cytogenetically normal (CN) acute myeloid leukemia (AML) is adversely affected by high expression of the ERG gene: A Cancer and Leukemia Group B (CALGB) study Paschka, P. , Marcucci, G. , Maharry, K. S. , Whitman, S. P. ... - EHA - Haematol-Hematol J - 2007 Abstract - Secondary - Primary - Leuk Corr Sci - CALGB-19808 , CALGB-20502 , CALGB-8461 , CALGB-9621 , CALGB-9665
Wilms Tumor 1 (WT1) Gene Mutations Predict Poor Outcome in Adults with Cytogenetically Normal (CN) Acute Myeloid Leukemia (AML): A Cancer and Leukemia Group B (CALGB) Study Paschka, P. , Marcucci, G. , Ruppert, A. S. , Mrozek, K. ... - - Blood - 2007 Abstract - Secondary - Primary - Leuk Corr Sci - CALGB-19808 , CALGB-20502 , CALGB-8461 , CALGB-9621 , CALGB-9665
Outcome prediction in adult core binding factor (CBF) acute myeloid leukemia (AML) with gene expression profiling: A Cancer and Leukemia Group B (CALGB) study Paschka, P. , Radmacher, M. D. , Marcucci, G. , Ruppert, A. S. ... - ASCO - J. Clin. Oncol. - 2007 Abstract - Secondary - Primary - Leuk Corr Sci - C8525 , C9022 , CALGB-19808 , CALGB-8461 , CALGB-9222 , CALGB-9621 , CALGB-9665
Wilms’ Tumor 1 Gene Mutations Independently Predict Poor Outcome in Adults With Cytogenetically Normal Acute Myeloid Leukemia: A Cancer and Leukemia Group B Study Paschka, Peter , Marcucci, Guido , Ruppert, Amy S. ... - - J Clin Oncol - 2008 Manuscript - Secondary - Primary - Leuk Corr Sci - CALGB-19808 , CALGB-20502 , CALGB-8461 , CALGB-9621 , CALGB-9665
High throughput digital quantification of mRNA abundance in primary human acute myeloid leukemia samples Payton, Jacqueline E. , Grieselhuber, Nicole R. , Chang, Li-Wei ... - - J Clin Invest - 2009 Manuscript - Secondary-not-in-original - Primary - Leuk Corr Sci - CALGB-8461 , CALGB-9665
MicroRNA (miR) expression signatures in molecular subsets of cytogenetically normal (CN) acute myeloid leukemia (AML): A Cancer and Leukemia Group B (CALGB) study Radmacher, M. D. , Marcucci, G. , Paschka, P. , Vukosavljevic, T. ... - - J. Clin. Oncol. - 2007 Abstract - Secondary - Primary - Leuk Corr Sci - CALGB-19808 , CALGB-20502 , CALGB-8461 , CALGB-9621 , CALGB-9665
Role and regulation of MicroRNAs targeting BTK in acute myelogenous leukemia Rizzotto, Lara , Lai, Tzung-Huei , Bottoni, Arianna ... - - Leuk. Lymphoma - 2018 Manuscript - - - Leuk Corr Sci - CALGB-8461
Aberrant Gene Expression of BAALC and ERG in Older >= 60 Years (y) De Novo Cytogenetically Normal Acute Myeloid Leukemia (CN-AML): A Cancer and Leukemia Group B (CALGB) Study Schwind, S. , Marcucci, G. , Maharry, K. , Mrozek, K. ... - - Blood - 2009 Abstract - Secondary - Primary - Leuk Corr Sci - CALGB-10201 , CALGB-20202 , CALGB-8461 , CALGB-9720
inv(16)/t(16;16) acute myeloid leukemia with non–type A CBFB-MYH11 fusions associate with distinct clinical and genetic features and lack KIT mutations Schwind, Sebastian , Edwards, Colin G. , Nicolet, Deedra ... - - Blood - 2013 Manuscript - Secondary - Primary - Leuk Corr Sci - CALGB-8461 , CALGB-8525 , CALGB-8821 , CALGB-8923 , CALGB-9022 , CALGB-9120 , CALGB-9222 , CALGB-9621 , CALGB-9720 , CALGB-19808 , CALGB-10201 , CALGB-10502 , CALGB-10503 , CALGB-10603
Prognostic Significance of Expression of a Single MicroRNA, miR-181a, in Cytogenetically Normal Acute Myeloid Leukemia: A Cancer and Leukemia Group B Study Schwind, Sebastian , Maharry, Kati , Radmacher, Michael D. ... - - J Clin Oncol - 2010 Manuscript - Secondary - Primary - Leuk Corr Sci - CALGB-19808 , CALGB-20202 , CALGB-20502 , CALGB-8461 , CALGB-9621 , CALGB-9665
Low expression of MN1 associates with better treatment response in older patients with de novo cytogenetically normal acute myeloid leukemia Schwind, Sebastian , Marcucci, Guido , Kohlschmidt, Jessica ... - - Blood - 2011 Manuscript - Secondary - Primary - Leuk Corr Sci - C8525 , CALGB-10201 , CALGB-20202 , CALGB-8461 , CALGB-8923 , CALGB-9420 , CALGB-9665 , CALGB-9720
Prognostic significance of initial clinical and molecular genetic features of acute promyelocytic leukemia (APL): Results from the North American Intergroup Trial, C9710 Stock, W. , Moser, B. K. , Powell, B. L. , Appelbaum, F. , Tallman, M. ... - ASCO - J. Clin. Oncol. - 2007 Abstract - Secondary-not-in-original - Primary - Leuk Corr Sci - C9710 , CALGB-8461 , CALGB-9665
What determines the outcomes for adolescents and young adults with acute lymphoblastic leukemia treated on cooperative group protocols? A comparison of Children's Cancer Group and Cancer and Leukemia Group B studies Stock, Wendy , La, Mei , Sanford, Ben , Bloomfield, Clara D. ... - - Blood - 2008 Manuscript - Secondary-not-in-original - Meta-Analysis - Leukemia - CALGB-8811 , CALGB-9331 , CALGB-19802 , CALGB-8461 , CALGB-9111 , CALGB-9511
The high prevalence of FLT3-ITD mutations is associated with the poor outcome in adult patients with t(6;9)(p23;q34) positive AML - Results of an international metaanalysis Thiede, C. , Bloomfield, C. D. , Lo Coco, F. , Frohling, S. ... - ASH - Blood - 2007 Abstract - Secondary-not-in-original - Comprehensive - Leuk Corr Sci - CALGB-19808 , CALGB-8461 , CALGB-9621 , CALGB-9665
The high prevalence of FLT3-ITD mutations is associated with the poor outcome in adult patients with t(6;9)(p23;q34) positive AML: Results of an international metaanalysis Thiede, C. , Bloomfield, C. D. , Lo Coco, F. , Frohling, S. ... - - Onkologie - 2007 Abstract - Secondary-not-in-original - Comprehensive - Leuk Corr Sci - CALGB-8461 , CALGB-9665
New Recurrent Balanced Translocations in Acute Myeloid Leukemia and Myelodysplastic Syndromes: Cancer and Leukemia Group B (CALGB) 8461 Walker, A. , Mrózek, K. , Kohlschmidt, J. , Rao, K. W. ... - - Genes Chromosomes Cancer - 2013 Manuscript - Secondary - Primary - Leuk Corr Sci - CALGB-8461
No evidence for microsatellite instability in acute myeloid leukemia Walker, Christopher J. , Eisfeld, Ann-Kathrin , Genutis, Luke K. ... - - Leukemia - 2017 Manuscript - Secondary-not-in-original - Primary - Leuk Corr Sci - CALGB-20202 , CALGB-8461 , CALGB-9665
Distinct Gene Expression Profiles and Mutations Are Associated with Disease Relapse after Achievement of Complete Remission (CR) in Adult Patients younger than 60 years with de novo Cytogenetically Normal Acute Myeloid Leukemia (CN-AML) (Alliance) Walker, Christopher J. , Eisfeld, Ann-Kathrin , Ozer, Hatice Gulcin ... - ASH - Blood - 2019 Abstract - Secondary-not-in-original - Primary - Leuk Corr Sci - CALGB-20202 , CALGB-8461 , CALGB-9665
Genetic Characterization and Prognostic Relevance of Acquired Uniparental Disomies in Cytogenetically Normal Acute Myeloid Leukemia Walker, Christopher J. , Kohlschmidt, Jessica , Eisfeld, Ann-Kathrin ... - - Clin. Cancer Res. - 2019 Manuscript - Secondary-not-in-original - Meta-Analysis - Leuk Corr Sci - C8721 , CALGB-10201 , CALGB-10502 , CALGB-10503 , CALGB-10603 , CALGB-19808 , CALGB-20202 , CALGB-8461 , CALGB-8525 , CALGB-8821 , CALGB-8923 , CALGB-9022 , CALGB-9222 , CALGB-9420 , CALGB-9621 , CALGB-9665 , CALGB-9720
High resolution array-based CGH and SNP studies of AML genomes Walter, M. J. , Ries, R. , Li, X. , Shannon, W. , Payton, J. ... - ASH - Blood - 2007 Abstract - Secondary - Primary - Leuk Corr Sci - CALGB-8461 , CALGB-9665
Autologous stem cell transplantation (SCT) following sequential chemotherapy and imatinib for adults with newly diagnosed philadelphia chromosome positive acute lymphoblastic leukemia (Ph+ ALL) - CALGB study 10001 Wetzler, M. , Stock, W. , Donohue, K. A. , Owzar, K. , Sher, D. A. ... - - Blood - 2007 Abstract - Primary - Primary - Leukemia - CALGB-10001 , CALGB-8461 , CALGB-9665 , CALGB-9862
Effective asparagine depletion with pegylated asparaginase results in improved outcomes in adult acute lymphoblastic leukemia: Cancer and Leukemia Group B Study 9511 Wetzler, Meir , Sanford, Ben L. , Kurtzberg, Joanne ... - - Blood - 2007 Manuscript - Secondary - Primary - Leuk Corr Sci - CALGB-8461 , CALGB-9511
Adverse Prognostic Impact of FLT3 Internal Tandem Duplication (ITD) Is Age-Associated in Older >= 60 Years (Y) De Novo cytogenetically Normal Acute Myeloid Leukemia (CN-AML) Patients (Pts): a Cancer and Leukemia Group B (CALGB) Study Whitman, S. P. , Maharry, K. , Radmacher, M. D. , Mrozek, K. ... - - Blood - 2009 Abstract - Secondary - Primary - Leuk Corr Sci - CALGB-10201 , CALGB-20202 , CALGB-8461 , CALGB-9720
Improved clinical outcome of cytogenetically normal acute myeloid leukemia patients with the MLL partial tandem duplication: A Cancer and Leukemia Group B (CALGB) study Whitman, S. P. , Ruppert, A. S. , Marcucci, G. , Mrozek, K. A. ... - - Cancer Res. - 2007 Abstract - Secondary-not-in-original - Primary - Leuk Corr Sci - CALGB-19808 , CALGB-20502 , CALGB-8461 , CALGB-9621 , CALGB-9665 , CALGB-9769
FLT3 D835/I836 mutations predict worse disease-free survival (DFS) in younger adults with cytogenetically normal acute myeloid leukemia (CN AML) without FLT3 internal tandem duplications (ITD): A Cancer and Leukemia Group B (CALGB) study Whitman, S. P. , Ruppert, A. S. , Radmacher, M. D. , Mrozek, K. A. ... - - J. Clin. Oncol. - 2007 Abstract - Secondary - Primary - Leuk Corr Sci - CALGB-19808 , CALGB-20502 , CALGB-8461 , CALGB-9621 , CALGB-9665
Adverse Prognostic Impact of GAS6 Expression in De Novo Cytogenetically Normal Acute Myeloid Leukemia (CN-AML) (CALGB 8461, 9665, 20202; Alliance) Whitman, S. , Kohlschmidt, J. , Maharry, K. , Nicolet, D. ... - - Blood - 2012 Abstract - Secondary - Primary - Leuk Corr Sci - CALGB-8461 , CALGB-9665 , CALGB-20202
Long-term disease-free survivors with cytogenetically normal acute myeloid leukemia and MLL partial tandem duplication: a Cancer and Leukemia Group B study Whitman, Susan P. , Ruppert, Amy S. , Marcucci, Guido ... - - Blood - 2007 Manuscript - Secondary - Primary - Leuk Corr Sci - CALGB-19808 , CALGB-20502 , CALGB-8461 , CALGB-9621 , CALGB-9665 , CALGB-9769
FLT3 D835/I836 mutations are associated with poor disease-free survival and a distinct gene-expression signature among younger adults with de novo cytogenetically normal acute myeloid leukemia lacking FLT3 internal tandem duplications Whitman, Susan P. , Ruppert, Amy S. , Radmacher, Michael D. ... - - Blood - 2008 Manuscript - Secondary - Primary - Leuk Corr Sci - CALGB-19808 , CALGB-20502 , CALGB-8461 , CALGB-9621 , CALGB-9665
Outcome of Adolescents and Young Adults with Acute Myeloid Leukemia Treated on COG Trials Compared to CALGB and SWOG Trials Woods, William G. , Franklin, Anna R.K. , Alonzo, Todd A. ... - - Cancer - 2013 Manuscript - Secondary-not-in-original - Meta-Analysis - Leukemia - CALGB-8525 , CALGB-9022 , CALGB-9222 , CALGB-9621 , CALGB-19808 , CALGB-8461