Expression and polymorphism (rs4880) of mitochondrial superoxide dismutase (SOD2) and asparaginase induced hepatotoxicity in adult patients with acute lymphoblastic leukemia Alachkar, Houda , Fulton, Noreen , Sanford, Ben , Malnassy, Greg ... - - Pharmacogenomics J. - 2017 Manuscript - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-10102
SPARC promotes leukemic cell growth and predicts acute myeloid leukemia outcome Alachkar, Houda , Santhanam, Ramasamy , Maharry, Kati ... - - J. Clin. Invest - 2014 Manuscript - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-19808 , CALGB-9621
Increased Expression of Macrophage Migration Inhibitory Factor (MIF) Receptor CD74 Is Associated with Inferior Outcome in Younger Patients (Pts) with Cytogenetically Normal Acute Myeloid Leukemia (CN-AML): a Cancer and Leukemia Group B (CALGB) Study Attar, E. C. , Maharry, K. , Mrozek, K. , Radmacher, M. D. ... - ASH - Blood - 2009 Abstract - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-10502 , CALGB-20202 , CALGB-20502 , CALGB-8461
Sole Trisomy 8 In Patients (pts) with De Novo Acute Myeloid Leukemia (AML) Is Associated with Age-Independent Poor Outcome That Is Modified by Molecular Markers and with Unique Gene- and Microrna (miR)-Signatures: a Cancer and Leukemia Group B (CALGB) Study Becker, H. , Maharry, K. , Radmacher, M. D. , Margeson, D. ... - - Blood - 2010 Abstract - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - C8525 , CALGB-10201 , CALGB-19808 , CALGB-20202 , CALGB-20502 , CALGB-8461 , CALGB-8923 , CALGB-9420 , CALGB-9621 , CALGB-9665 , CALGB-9720
NPM1 mutations as an independent prognosticator for older cytogenetically normal acute myeloid leukemia (CN AML) Becker, H. , Marcucci, G. , Maharry, K. , Margeson, D. ... - - J. Clin. Oncol. - 2009 Abstract - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-10201 , CALGB-20202 , CALGB-8461 , CALGB-9720
CEBPA double mutations impact favorably on the outcome of older adults with wild-type NPM1 cytogenetically normal acute myeloid leukemia and are associated with distinct gene- and microRNA-expression patterns Becker, H. , Marcucci, G. , Maharry, K. , Radmacher, M. , Wu, Y. ... - - Haematologica - 2010 Abstract - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - C8525 , CALGB-10201 , CALGB-20202 , CALGB-20502 , CALGB-8461 , CALGB-8923 , CALGB-9420 , CALGB-9665 , CALGB-9720
Prognostic gene mutations and distinct gene- and microRNA-expression signatures in acute myeloid leukemia with a sole trisomy 8 Becker, Heiko , Maharry, Kati , Mrózek, Krzysztof , Volinia, Stefano ... - - Leukemia - 2014 Manuscript - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - C8525 , CALGB-10201 , CALGB-10502 , CALGB-10503 , CALGB-10603 , CALGB-19808 , CALGB-8923 , CALGB-9022 , CALGB-9222 , CALGB-9420 , CALGB-9621 , CALGB-9720
Clinical outcome and gene- and microRNA-expression profiling according to the Wilms tumor 1 (WT1) single nucleotide polymorphism rs16754 in adult de novo cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study Becker, Heiko , Maharry, Kati , Radmacher, Michael D. ... - - Haematologica - 2011 Manuscript - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - C8525 , CALGB-10201 , CALGB-19808 , CALGB-20202 , CALGB-20502 , CALGB-8461 , CALGB-8923 , CALGB-9420 , CALGB-9621 , CALGB-9665 , CALGB-9720
Mutations of the Wilms tumor 1 gene (WT1) in older patients with primary cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study Becker, Heiko , Marcucci, Guido , Maharry, Kati ... - - Blood - 2010 Manuscript - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - C8525 , CALGB-10201 , CALGB-19808 , CALGB-20202 , CALGB-8461 , CALGB-8923 , CALGB-9420 , CALGB-9621 , CALGB-9665 , CALGB-9720
Favorable Prognostic Impact of NPM1 Mutations in Older Patients With Cytogenetically Normal De Novo Acute Myeloid Leukemia and Associated Gene- and MicroRNA-Expression Signatures: A Cancer and Leukemia Group B Study Becker, Heiko , Marcucci, Guido , Maharry, Kati ... - - J Clin Oncol - 2010 Manuscript - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-10201 , CALGB-19808 , CALGB-20202 , CALGB-8461 , CALGB-9720
Clinical features and gene- and microRNA-expression patterns in adult acute leukemia patients with t(11;19)(q23;p13.1) and t(11;19)(q23;p13.3) Bhatnagar, B , Blachly, JS , Kohlschmidt, J , Eisfeld, A-K ... - - Leukemia - 2016 Manuscript - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - C8461 , CALGB-20202 , C8525 , CALGB-10102 , CALGB-10201 , CALGB-10503 , CALGB-10603 , CALGB-11002 , CALGB-19808 , CALGB-8923 , CALGB-9120 , CALGB-9222 , CALGB-9621 , CALGB-9720
Acute myeloid leukemia (AML) patients with an isolated trisomy display increased frequency of spliceosome mutations CALGB 8461 and 20202 (Alliance) Bhatnagar, Bhavana , Eisfeld, Ann-Kathrin , Mrózek, Krzysztof ... - ASH - Blood - 2017 Abstract - Secondary-not-in-original Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-20202 , CALGB-8461
Persistence of DNMT3A R882 mutations during remission does not adversely affect outcomes of patients with acute myeloid leukaemia Bhatnagar, Bhavana , Eisfeld, Ann-Kathrin , Nicolet, Deedra ... - - Br. J. Haematol. - 2016 Manuscript - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-20202 , CALGB-10201 , CALGB-10502 , CALGB-10503 , CALGB-10603 , CALGB-19808 , CALGB-9222 , CALGB-9621 , CALGB-9720
Mutational Landscape and Clinical Outcome Associated with Different Rearrangements Involving 11q23/MLL in De Novo Acute Myeloid Leukemia (AML) CALB 8461 and 20202 (Alliance) Bill, Marius , Eisfeld Ann-Kathrin , Mrózek Krzysztof ... - ASH - Blood - 2017 Abstract - Secondary-not-in-original Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-20202 , CALGB-8461
Prognostic impact of the 2017 European Leukemianet (ELN) classification of adult patients (pts) with acute myeloid leukemia (AML) treated on Cancer and Leukemia Group B (CALGB)/Alliance protocols Bill, Marius , Mrózek, K , Kohlschmidt, J. , Nicolet, D. ... - EHA - HemaSphere - 2019 Abstract - Secondary-not-in-original Endpoint - Meta-Analysis Analysis - Leuk Corr Sci - C8461 , CALGB-20202 , CALGB-9665
A 17-gene leukemia stem cell (LSC) score in adult patients (pts) with acute myeloid leukemia (AML) reveals a distinct mutational landscape and refines current European Leukemianet (ELN) genetic risk stratification (Alliance) Bill, Marius , Nicolet, Deedra , Eisfeld, Ann-Kathrin ... - ASH - Blood - 2018 Abstract - Secondary-not-in-original Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-20202 , CALGB-8461
Mutations associated with a 17-gene leukemia stem cell score and its prognostic relevance in the context of the European LeukemiaNet classification for acute myeloid leukemia. Bill, Marius , Nicolet, Deedra , Kohlschmidt, Jessica ... - - Haematologica - 2019 Manuscript - Secondary-not-in-original Endpoint - Primary Analysis - Leuk Corr Sci - C8621 , CALGB-8461 , C8721 , CALGB-10201 , CALGB-10502 , CALGB-10503 , CALGB-10603 , CALGB-11001 , CALGB-11002 , CALGB-19808 , CALGB-20202 , CALGB-8525 , CALGB-8821 , CALGB-8923 , CALGB-9022 , CALGB-9120 , CALGB-9222 , CALGB-9420 , CALGB-9621 , CALGB-9665 , CALGB-9720
Prognostic and biologic significance of transfer RNA-derived small RNAs(tsRNAs) expression in younger adult patients (pts) with cytogenetically normal acute myeloid leukemia (CN-AML) Bill, Marius , Veneziano, Dario , Kohlschmidt, Jessica ... - ASH - Blood - 2018 Abstract - Secondary-not-in-original Endpoint - Primary Analysis - Leuk Corr Sci - C8461 , C9665 , CALGB-20202
Silencing of the inhibitor of DNA binding protein 4 (ID4) contributes to the pathogenesis of mouse and human CLL Chen, S. S. , Claus, R. , Lucas, D. M. , Yu, L. , Qian, J. ... - - Blood - 2011 Manuscript - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - C9665 , C20305 , C9712
Quantitative DNA methylation analysis identifies a single CpG dinucleotide important for ZAP-70 expression and predictive of prognosis in chronic lymphocytic leukemia Claus, R. , Lucas, D. M. , Stilgenbauer, S. , Ruppert, A. S. , Yu, L. ... - - J. Clin. Oncol. - 2012 Manuscript - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - C9712
Acute Myeloid Leukemia (AML) with 9q aberrations occuring within a non-complex karyotype is highly associated with CEBPA and NPM1 mutations - A joint analysis of the German-Austrian AML Study Group (AMLSG) and Cancer and Leukemia Group B (CALGB) Corbacioglu, A. , Frohling, S. , Paschka, P. , Marcucci, G. ... - ASH - Blood - 2007 Abstract - Secondary-not-in-original Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-19808 , CALGB-8461 , CALGB-9621 , CALGB-9665
Clinical impact of ABL1 kinase domain mutations and IKZF1 deletion in adults under age 60 with Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL): molecular analysis of CALGB (Alliance) 10001 and 9665 DeBoer, Rebecca , Koval, Gregory , Mulkey, Flora , Wetzler, Meir ... - - Leuk. Lymphoma - 2016 Manuscript - Secondary-not-in-original Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-10001 , C9665
Clinical impact of ABL1 kinase and IKZF1 mutations in adults with Philadelphia chromosome-positive (PH+) acute lymphoblastic leukemia (ALL): molecular analysis of CALGB 10001 and 9665 (Alliance) DeBoer, Rebecca , Mulkey, Flora , Koval, Gregory , Wetzler, Meir ... - EHA - Haematologica - 2014 Abstract - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-10001 , CALGB-9665
Impact of NPM1/FLT3-ITD genotypes defined by the 2017 European LeukemiaNet in patients with acute myeloid leukemia. Döhner, Konstanze , Thiede, Christian , Jahn, Nikolaus ... - - Blood - 2019 Manuscript - No-Endpoint Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-10603
Cytogenetic, Molecular and Clinical Features Associated with Rare CBFB-MYH11 Fusion Transcripts in Patients (Pts) with Acute Myeloid Leukemia (AML) and inv(16)/t(16;16) Edwards, C. G. , Maharry, K. , Mrozek, K. , Schwind, S. , Paschka, P. ... - - Blood - 2011 Abstract - Primary Endpoint - Comprehensive Analysis - Leuk Corr Sci - CALGB-10503 , CALGB-19808 , CALGB-9621
The mutational oncoprint of recurrent cytogenetic abnormalities in adult patients with de novo acute myeloid leukemia Eisfeld, A-K , Mrózek, K , Kohlschmidt, J , Nicolet, D , Orwick, S ... - - Leukemia - 2017 Manuscript - Secondary-not-in-original Endpoint - Comprehensive Analysis - Leuk Corr Sci - CALGB-20202 , CALGB-8461 , CALGB-9665
Adult acute myeloid leukemia with trisomy 11 as the sole abnormality is characterized by the presence of five distinct gene mutations: MLL-PTD, DNMT3A, U2AF1, FLT3-ITD and IDH2 Eisfeld, Ann-Kathrin , Kohlschmidt, Jessica , Mrózek, Krzysztof ... - - Leukemia - 2016 Manuscript - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-20202 , CALGB-8461
Mutation patterns identify adult patients with de novo acute myeloid leukemia aged 60 years or older who respond favorably to standard chemotherapy: an analysis of Alliance studies Eisfeld, Ann-Kathrin , Kohlschmidt, Jessica , Mrózek, Krzysztof ... - - Leukemia - 2018 Manuscript - Secondary-not-in-original Endpoint - Comprehensive Analysis - Leuk Corr Sci - C8461 , C8525 , C8821 , C9665 , CALGB-10201 , CALGB-10502 , CALGB-11001 , CALGB-11002 , CALGB-20202 , CALGB-8461 , CALGB-8923 , CALGB-9420 , CALGB-9720
NF1 mutations are recurrent in adult acute myeloid leukemia and confer poor outcome Eisfeld, Ann-Kathrin , Kohlschmidt, Jessica , Mrózek, Krzysztof ... - - Leukemia - 2018 Manuscript - Secondary-not-in-original Endpoint - Comprehensive Analysis - Leuk Corr Sci - C8525 , C8821 , C9022 , C9621 , C9720 , CALGB-10201 , CALGB-10502 , CALGB-10503 , CALGB-10603 , CALGB-19808 , CALGB-8923
Additional gene mutations refine the 2017 European Leukemianet (ELN) classification of adult patients (pts) with de novo acute myeloid leukemia (AML) aged <60 years: An analysis of Alliance studies Eisfeld, Ann-Kathrin , Kohlschmidt, Jessica , Mrózek, Krzysztof ... - ASH - Blood - 2018 Abstract - Secondary-not-in-original Endpoint - Primary Analysis - Leuk Corr Sci - C8461 , CALGB-20202
Mutations in genes associated with familial predisposition to myeloid neoplasms:their frequency and associations with pretreatment characteristics in adult patients (pts) with presumably sporadic de novo acute myeloid leukemia (AML) (Alliance) Eisfeld, Ann-Kathrin , Kohlschmidt, Jessica , Mrózek, Krzysztof ... - ASH - Blood - 2018 Abstract - Secondary-not-in-original Endpoint - Primary Analysis - Leuk Corr Sci - C8461 , CALGB-20202
Mutational landscape and gene-expression patterns in adult acute myeloid leukemias with monosomy 7 as a sole abnormality Eisfeld, Ann-Kathrin , Kohlschmidt, Jessica , Mrózek, Krzysztof ... - - Cancer Res. - 2017 Manuscript - Secondary-not-in-original Endpoint - Meta-Analysis Analysis - Leuk Corr Sci - CALGB-10201 , CALGB-10503 , CALGB-10603 , CALGB-11002 , CALGB-19808 , CALGB-20202 , CALGB-8461 , CALGB-8525 , CALGB-9222 , CALGB-9420 , CALGB-9621
Mutations in the CCND1 and CCND2 genes are frequent events in adult patients with t(8;21)(q22;q22) acute myeloid leukemia Eisfeld, Ann-Kathrin , Kohlschmidt, Jessica , Schwind, Sebastian ... - - Leukemia - 2017 Manuscript - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-20202 , CALGB-8461 , CALGB-9665
Heritable polymorphism predisposes to high expression of BAALC in cytogenetically normal acute myeloid leukemia (CN-AML) Eisfeld, Ann-Kathrin , Marcucci, G. , Liyanarachchi, S. , Döhner, K. ... - AACR - AACR Annual Meeting - 2012 Abstract - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - C9665
MiR-3151, a novel microRNA embedded in BAALC, is only weakly co-xxpressed with its host gene and independently impacts on the clinical outcome of older patients (pts) with de novo cytogenetically normal acute myeloid leukemia (CN-AML) Eisfeld, Ann-Kathrin , Marcucci, G. , Maharry, K. , Schwind, S. ... - - Blood - 2011 Abstract - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - C8525 , CALGB-10201 , CALGB-8923 , CALGB-9420 , CALGB-9720
Heritable polymorphism predisposes to high BAALC expression in acute myeloid leukemia Eisfeld, Ann-Kathrin , Marcucci, Guido , Liyanarachchi, Sandya ... - - Proc. Natl. Acad. Sci. U.S.A - 2012 Manuscript - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-9665
miR-3151 interplays with its host gene BAALC and independently affects outcome of patients with cytogenetically normal acute myeloid leukemia Eisfeld, Ann-Kathrin , Marcucci, Guido , Maharry, Kati ... - - Blood - 2012 Manuscript - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-9665
Treatment-influenced associations of PML-RARalpha mutations, FLT3 mutations, and additional chromosome abnormalities in relapsed acute promyelocytic leukemia Gallagher, R. E. , Moser, B. K. , Racevskis, J. , Poire, X. ... - - Blood - 2012 Manuscript - Secondary-not-in-original Endpoint - Primary Analysis - Leuk Corr Sci - C9710
Clonal Markers In Relapsed Acute Promyelocytic Leukemia (APL): Clinicopathological Associations and Relation to All-Trans Retinoic Acid (ATRA) Treatment on Intergroup Phase III Trial C9710 Gallagher, R. E. , Moser, B. K. , Racevskis, J. , Poire, X. ... - - Blood - 2010 Abstract - Secondary-not-in-original Endpoint - Primary Analysis - Leuk Corr Sci - C9710
Expression and prognostic impact of lncRNAs in acute myeloid leukemia Garzon, Ramiro , Volinia, Stefano , Papaioannou, Dimitrios ... - - Proc. Natl. Acad. Sci. U.S.A - 2014 Manuscript - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-20202
Dual Epigenetic Control of CCAAT/Enhancer Binding Protein {alpha} (C/EBP{alpha}) Expression in Acute Myeloid Leukemia Hackanson, B. , Bennett, K. L. , Brena, R. M. , Jiang, J. ... - - Blood - 2007 Abstract - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-19808 , CALGB-20502 , CALGB-8461 , CALGB-9621 , CALGB-9665
Epigenetic modification of CCAAT/enhancer binding protein alpha expression in acute myeloid leukemia. Hackanson, Björn , Bennett, Kristi L , Brena, Romulo M ... - - Cancer Res. - 2008 Manuscript - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-8461 , CALGB-9665
Application of 2008 WHO classification criteria for myelodysplastic syndromes (MDS) without excess blasts: Observations from Cancer and Leukemia Group B Study 10105 Hasserjian, R. , Gupta, P. , Donohue, K. A. , Owzar, K. ... - USCAP - United States and Canadian Academy of Pathology Annual Meeting - 2009 Abstract - Secondary-not-in-original Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-10105
Implications of the miR-10 family in chemotherapy response of NPM1-mutated AML Havelange, Violaine , Ranganathan, Parvathi , Geyer, Susan ... - - Blood - 2014 Manuscript - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - C8525 , C9720 , CALGB-10201 , CALGB-8923 , CALGB-9420
Lenalidomide-mediated enhanced translation of C/EBPα-p30 protein up-regulates expression of the antileukemic microRNA-181a in acute myeloid leukemia Hickey, Christopher J. , Schwind, Sebastian , Radomska, Hanna S. ... - - Blood - 2013 Manuscript - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-9621 , CALGB-19808
Genetic landscape of flt3-mutated acute myeloid leukemia (AML) patients treated within the ratify trial (Alliance C10603) Jahn, Nikolaus , Panina, Ekaterina , Bullinger, Lars , Dolnik, Anna ... - EHA - HemaSphere - 2019 Abstract - Secondary-not-in-original Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-10603
Comprehensive molecular profiling of FLT3-mutated acute myeloid leukemia (AML) patients treated within the RATIFY trial (Alliance) Jahn, Nikolaus , Panina, Ekaterina , Bullinger, Lars , Dolnik, Anna ... - ASH - Blood - 2018 Abstract - Secondary-not-in-original Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-10603
A variant allele of Growth Factor Independence 1 (GFI1) is associated with acute myeloid leukemia Khandanpour, C. , Thiede, C. , Valk, P. J. , Sharif-Askari, E. ... - - Blood - 2010 Manuscript - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - C9665 , C8461
Abl Kinase Domain Mutations Leading to Relapse of Ph+ Acute Lymphoblastic Leukemia (ALL) Occur Commonly and Can Be Detected At Initial Diagnosis: Molecular Results From CALGB 10001 Koval, G. , Wetzler, M. , Watson, D. , Owzar, K. , Bloomfield, C. D. ... - - Blood - 2011 Abstract - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-10001
FLT3 mutation status is a predictor of early death in pediatric acute promyelocytic leukemia: a report from the Children's Oncology Group Kutny, M. A. , Moser, B. K. , Laumann, K. , Feusner, J. H. , Gamis, A. ... - - Pediatr Blood Cancer - 2012 Manuscript - Secondary-not-in-original Endpoint - Primary Analysis - Leuk Corr Sci - C9710
High expression of IGFBP2 is associated with chemoresistance in adult acute myeloid leukemia Kühnl, Andrea , Kaiser, Martin , Neumann, Martin , Fransecky, Lars ... - - Leuk. Res. - 2011 Manuscript - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - C9665 , C20202 , C9621 , C8461
Low Meningioma 1 (MN1) gene expression to predict outcome in cytogenetically normal acute myeloid leukemia (CN-AML): A Cancer and Leukemia Group B (CALGB) study Langer, C. , Maharry, K. S. , Mrozek, K. A. , Paschka, P. ... - - J. Clin. Oncol. - 2008 Abstract - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-19808 , CALGB-20502 , CALGB-9621
High BAALC expression associates with other molecular prognostic markers, poor outcome and a distinct gene expression signature in cytogenetically normal acute myeloid leukemia (CN AML): A Cancer and Leukemia Group B (CALGB) study Langer, C. , Ruppert, A. S. , Radmacher, M. D. , Whitman, S. P. ... - - J. Clin. Oncol. - 2007 Abstract - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-19808 , CALGB-20502 , CALGB-8461 , CALGB-9621 , CALGB-9665
Prognostic Importance of MN1 Transcript Levels, and Biologic Insights From MN1-Associated Gene and MicroRNA Expression Signatures in Cytogenetically Normal Acute Myeloid Leukemia: A Cancer and Leukemia Group B Study Langer, Christian , Marcucci, Guido , Holland, Kelsi B. ... - - J Clin Oncol - 2009 Manuscript - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-19808 , CALGB-20502 , CALGB-8461 , CALGB-9621 , CALGB-9665
High BAALC expression associates with other molecular prognostic markers, poor outcome, and a distinct gene-expression signature in cytogenetically normal patients younger than 60 years with acute myeloid leukemia: a Cancer and Leukemia Group B (CALGB) study Langer, Christian , Radmacher, Michael D. , Ruppert, Amy S. ... - - Blood - 2008 Manuscript - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-19808 , CALGB-20502 , CALGB-8461 , CALGB-9621 , CALGB-9665
DNMT3A mutations in acute myeloid leukemia Ley, T. J. , Ding, L. , Walter, M. J. , Mclellan, M. D. ... - - N. Engl. J. Med. - 2010 Manuscript - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - C9665 , C8461
DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome Ley, T. J. , Mardis, E. R. , Ding, L. , Fulton, B. , Mclellan, M. D. ... - - Nature - 2008 Manuscript - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - C9665 , C8461
Up-regulation of a HOXA-PBX3 homeobox-gene signature following down-regulation of miR-181 is associated with adverse prognosis in patients with cytogenetically abnormal AML Li, Z. , Huang, H. , Li, Y. , Jiang, X. , Chen, P. , Arnovitz, S. ... - - Blood - 2012 Manuscript - Secondary-not-in-original Endpoint - Primary Analysis - Leuk Corr Sci - C9665
Activation of a Mir-181-Targeting HOXA-PBX3 Homeobox Gene Signature Is Associated with Adverse Prognosis of Cytogenetically Abnormal Acute Myeloid Leukemia Li, Z. , Huang, H. , Li, Y. , Jiang, X. , Chen, P. , Arnovitz, S. ... - ASH - ASH Annual Meeting Abstracts - 2011 Abstract - Secondary-not-in-original Endpoint - Primary Analysis - Leuk Corr Sci - C9665
Distinct patterns of mutations occurring in de novo AML versus AML arising in the setting of severe congenital neutropenia Link, Daniel C. , Kunter, Ghada , Kasai, Yumi , Zhao, Yu ... - - Blood - 2007 Manuscript - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-8461 , CALGB-9665
Sp1/NFκB/HDAC/miR-29b Regulatory Network in KIT-driven Myeloid Leukemia Liu, Shujun , Wu, Lai-Chu , Pang, Jiuxia , Santhanam, Ramasamy ... - - Cancer Cell - 2010 Manuscript - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - C9665
Chromosome 5q deletion and epigenetic suppression of the gene encoding alpha-catenin (CTNNA1) in myeloid cell transformation. Liu, Ting Xi , Becker, Michael W , Jelinek, Jaroslav , Wu, Wen-Shu ... - - Nat. Med. - 2007 Manuscript - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-8461 , CALGB-9665
The genetic landscape of mutations in Burkitt lymphoma Love, Cassandra , Sun, Zhen , Jima, Dereje , Li, Guojie , Zhang, Jenny ... - - Nat. Genet. - 2012 Manuscript - Secondary-not-in-original Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-10002
Quantitative Measurement of CD52 Expression and Alemtuzumab Binding in Adult Acute Lymphoblastic Leukemia (ALL): Correlation with Immunophenotype and Cytogenetics in Patients (Pts) Enrolled on a Phase I/II Trial from the Cancer and Leukemia Group B (CALGB 10102) Lozanski, G. , Sanford, B. , Mrozek, K. , Edwards, C. , Pearson, R. ... - ASH - Blood - 2007 Abstract - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-10102 , CALGB-8461 , CALGB-9665 , CALGB-9862
Variations of the ataxia telangiectasia mutated gene in patients with chronic lymphocytic leukemia lack substantial impact on progression-free survival and overall survival: a Cancer and Leukemia Group B study Lozanski, Gerard , Ruppert, Amy S. , Heerema, Nyla A. ... - - Leuk. Lymphoma - 2012 Manuscript - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-9712 , CALGB-9665
Comparison Of Deep Sequencing and Allele-Specific Oligonucleotide PCR Methods For MRD Quantitation In Acute Lymphoblastic Leukemia and Mantle Cell Lymphoma: CALGB 10403 and CALGB 59909 (Alliance) Malnassy, Greg , Geyer, Susan , Fulton, Noreen , Koval, Greg ... - - Blood - 2013 Abstract - Secondary-not-in-original Endpoint - Meta-Analysis Analysis - Leuk Corr Sci - CALGB-10403 , CALGB-59909
Improving the molecular risk classification for younger (<60 years) de novo cytogenetically normal acute myeloid leukemia (CN AML) patients (pts) Marcucci, G. , Maharry, K. S. , Whitman, S. P. , Paschka, P. ... - ASCO - J. Clin. Oncol. - 2009 Abstract - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-19808 , CALGB-20202 , CALGB-9621
High ERG expression levels predict adverse outcome and refine molecular risk-based classification of cytogenetically normal (CN) acute myeloid leukemia (AML): A Cancer and Leukemia Group B (CALGB) study Marcucci, G. , Maharry, K. S. , Whitman, S. P. , Vukosavljevic, T. ... - AACR - AACR Annual Meeting - 2007 Abstract - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-19808 , CALGB-20502 , CALGB-8461 , CALGB-9621 , CALGB-9665
IDH1 and IDH2 gene mutations identify novel molecular subsets within de novo cytogenetically normal acute myeloid leukemia (CN-AML): A Cancer and Leukemia Group B (CALGB) Study Marcucci, G. , Maharry, K. S. , Wu, Y. , Radmacher, M. D. ... - - Haematologica - 2010 Abstract - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - C8525 , CALGB-10201 , CALGB-19808 , CALGB-20202 , CALGB-20502 , CALGB-8461 , CALGB-8923 , CALGB-9420 , CALGB-9621 , CALGB-9665 , CALGB-9720
Gene and microRNA (miRNA) Expression Signatures and Prognostic Significance of CEBPA Mutations in Cytogenetically Normal (CN) Acute Myeloid Leukemia (AML) with High-Risk Molecular Features: A Cancer and Leukemia Group B (CALGB) Study Marcucci, G. , Maharry, K. , Radmacher, M. D. , Mrozek, K. ... - - Blood - 2007 Abstract - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-19808 , CALGB-20205 , CALGB-20502 , CALGB-8461 , CALGB-9621 , CALGB-9665
Adding The KIT Inhibitor Dasatinib (DAS) To Standard Induction and Consolidation Therapy For Newly Diagnosed Patients (pts) With Core Binding Factor (CBF) Acute Myeloid Leukemia (AML): Initial Results Of The CALGB 10801 (Alliance) Study Marcucci, Guido , Geyer, Susan , Zhao, John , Caroll, Andrew J ... - ASH - Blood - 2013 Abstract - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-10801
Clinical Role of microRNAs in Cytogenetically Normal Acute Myeloid Leukemia: miR-155 Upregulation Independently Identifies High-Risk Patients Marcucci, Guido , Maharry, Kati S. , Metzeler, Klaus H. ... - - J. Clin. Oncol. - 2013 Manuscript - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-8461 , CALGB-9665 , CALGB-20202
Prognostic Significance of, and Gene and MicroRNA Expression Signatures Associated With, CEBPA Mutations in Cytogenetically Normal Acute Myeloid Leukemia With High-Risk Molecular Features: A Cancer and Leukemia Group B Study Marcucci, Guido , Maharry, Kati , Radmacher, Michael D. ... - - J Clin Oncol - 2008 Manuscript - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-19808 , CALGB-20502 , CALGB-8461 , CALGB-9621 , CALGB-9665
High expression levels of the ETS-related gene, ERG, predict adverse outcome and improve molecular risk-based classification of cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B Study. Marcucci, Guido , Maharry, Kati , Whitman, Susan P ... - - J. Clin. Oncol. - 2007 Manuscript - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-19808 , CALGB-20205 , CALGB-20502 , CALGB-8461 , CALGB-9621 , CALGB-9665
IDH1 and IDH2 Gene Mutations Identify Novel Molecular Subsets Within De Novo Cytogenetically Normal Acute Myeloid Leukemia: A Cancer and Leukemia Group B Study Marcucci, Guido , Maharry, Kati , Wu, Yue-Zhong ... - - J Clin Oncol - 2010 Manuscript - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - C8421 , C8525 , CALGB-10201 , CALGB-19808 , CALGB-20202 , CALGB-20502 , CALGB-8923 , CALGB-9420 , CALGB-9621 , CALGB-9665 , CALGB-9720
Age-Related Prognostic Impact of Different Types of DNMT3A Mutations in Adults With Primary Cytogenetically Normal Acute Myeloid Leukemia Marcucci, Guido , Metzeler, Klaus H. , Schwind, Sebastian ... - - J. Clin. Oncol. - 2012 Manuscript - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-9621 , CALGB-19808
MicroRNA expression in cytogenetically normal acute myeloid leukemia. Marcucci, Guido , Radmacher, Michael D , Maharry, Kati ... - - N. Engl. J. Med. - 2008 Manuscript - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-19808 , CALGB-20502 , CALGB-8461 , CALGB-9621 , CALGB-9665
Epigenetics Meets Genetics in Acute Myeloid Leukemia: Clinical Impact of a Novel Seven-Gene Score Marcucci, Guido , Yan, Pearlly , Maharry, Kati , Frankhouser, David ... - - J. Clin. Oncol - 2014 Manuscript - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-10201 , CALGB-9420 , CALGB-9720 , CALGB-9621 , CALGB-19808
Recurring mutations found by sequencing an acute myeloid leukemia genome Mardis, E. R. , Ding, L. , Dooling, D. J. , Larson, D. E. ... - - N. Engl. J. Med. - 2009 Manuscript - Secondary-not-in-original Endpoint - Primary Analysis - Leuk Corr Sci - C9665 , C8461
Influence of 6q22-23 on overall survival in primary central nervous system lymphoma. Analysis of North Central Cancer Treatment Group trials 86 72 52, 93 73 51 and 96 73 51 McPhail, Ellen R. , Law, Mark E. , Decker, Paul A. ... - - Br. J. Haematol. - 2011 Manuscript - Secondary-not-in-original Endpoint - Primary Analysis - Leuk Corr Sci - NCCTG-86-72-52 , 93-73-51 , 96-73-51
Poor Outcome of RUNX1-Mutated (RUNX1-mut) Patients (Pts) with Primary, Cytogenetically Normal Acute Myeloid Leukemia (CN-AML) and Associated Gene- and MicroRNA (miR) Expression Signatures Mendler, J. H. , Maharry, K. , Radmacher, M. D. , Mrozek, K. ... - - Blood - 2011 Abstract - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - C8525 , CALGB-10201 , CALGB-19808 , CALGB-8923 , CALGB-9420 , CALGB-9621 , CALGB-9720
RUNX1 Mutations Are Associated With Poor Outcome in Younger and Older Patients With Cytogenetically Normal Acute Myeloid Leukemia and With Distinct Gene and MicroRNA Expression Signatures Mendler, Jason H. , Maharry, Kati , Radmacher, Michael D. ... - - J. Clin. Oncol. - 2012 Manuscript - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - C8525 , CALGB-8461 , CALGB-8923 , CALGB-9420 , CALGB-9621 , CALGB-9665 , CALGB-9720 , CALGB-10201 , CALGB-19808 , CALGB-20202
ASXL1 Mutations Identify a High-Risk Subgroup of Older Patients with Primary Cytogenetically Normal Acute Myeloid Leukemia within the European LeukemiaNet 'Favorable' Genetic Category Metzeler, K. H. , Becker, H. , Maharry, K. , Radmacher, M. D. ... - - Blood - 2011 Abstract - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-20202 , CALGB-8461 , CALGB-9665
An 86-Probe Gene Expression Signature Can Predict Survival in AML with Normal Karyotype Independently of FLT3 ITD and NPM1 Mutation Status - A Collaborative Study from the AMLCG and CALGB Study Groups Metzeler, K. H. , Hummel, M. , Bloomfield, C. D. , Spiekermann, K. ... - - Blood - 2007 Abstract - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-8461 , CALGB-9621 , CALGB-9665
TET2 mutations occur in over 20% of adults with de novo cytogenetically normal AML, and their prevalence increases with age: A Cancer and Leukemia Goup B study. Metzeler, K. H. , Maharry, K. , Margeson, D. , Curfman, J. ... - - Haematologica - 2010 Abstract - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - C8525 , CALGB-10201 , CALGB-19808 , CALGB-20202 , CALGB-20502 , CALGB-8461 , CALGB-8923 , CALGB-9420 , CALGB-9621 , CALGB-9665 , CALGB-9720
Mutations In the Tet Oncogene Family Member 2 (TET2) Gene Refine the New European LeukemiaNet Risk Classification of Primary, Cytogenetically Normal Acute Myeloid Leukemia (CN-AML) In Adults: A Cancer and Leukemia Group B (CALGB) Study Metzeler, K. H. , Maharry, K. , Radmacher, M. D. , Mrozek, K. ... - - Blood - 2010 Abstract - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - C8525 , C8641 , CALGB-10201 , CALGB-19808 , CALGB-20202 , CALGB-20502 , CALGB-8923 , CALGB-9420 , CALGB-9621 , CALGB-9665 , CALGB-9720
A stem cell-like gene expression signature associates with inferior outcomes and a distinct microRNA expression profile in adults with primary cytogenetically normal acute myeloid leukemia Metzeler, KH , Maharry, K , Kohlschmidt, J , Volinia, S , Mrózek, K ... - - Leukemia - 2013 Manuscript - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-8461 , CALGB-9665 , CALGB-20202
ASXL1 mutations identify a high-risk subgroup of older patients with primary cytogenetically normal AML within the ELN Favorable genetic category Metzeler, Klaus H. , Becker, Heiko , Maharry, Kati ... - - Blood - 2011 Manuscript - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-20202 , CALGB-8461 , CALGB-9665
An 86-probe-set gene-expression signature predicts survival in cytogenetically normal acute myeloid leukemia Metzeler, Klaus H. , Hummel, Manuela , Bloomfield, Clara D. ... - - Blood - 2008 Manuscript - Secondary-not-in-original Endpoint - Meta-Analysis Analysis - Leuk Corr Sci - CALGB-8461 , CALGB-9621 , CALGB-9665
TET2 Mutations Improve the New European LeukemiaNet Risk Classification of Acute Myeloid Leukemia: A Cancer and Leukemia Group B Study Metzeler, Klaus H. , Maharry, Kati , Radmacher, Michael D. ... - - J Clin Oncol - 2011 Manuscript - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - C8525 , CALGB-10201 , CALGB-19808 , CALGB-20202 , CALGB-20502 , CALGB-8461 , CALGB-8923 , CALGB-9420 , CALGB-9621 , CALGB-9665 , CALGB-9720
Development and Validation of a Dominant Clone Precision Medicine Classification for Treatment of Elderly Acute Myeloid Leukemia (Alliance) Mims, Alice S. , Borate, Uma , Kohlschmidt, Jessica , Norris, Brianna ... - ASH - Blood - 2018 Abstract - Secondary-not-in-original Endpoint - Primary Analysis - Leuk Corr Sci - C8461 , CALGB-20202
Comparisons between TP53 mutations and TP73 mutations in adult acute myeloid leukemia (AML) (Alliance) Mims, Alice S. , Kohlschmidt, Jessica , Eisfeld, Ann-Kathrin ... - ASH - Blood - 2018 Abstract - Secondary-not-in-original Endpoint - Primary Analysis - Leuk Corr Sci - C8461 , CALGB-20202
Prognostic Significance of Unbalanced Chromosome Abnormalities Used by 2008 World Health Organization (WHO) Classification to Define Acute Myeloid Leukemia (AML) with Myelodysplasia-Related Changes in Adults: a Cancer and Leukemia Group B (CALGB) Study Mrozek, K. , Holland, K. B. , Pettenati, M. J. , Maharry, K. ... - ASH - Blood - 2009 Abstract - Secondary-not-in-original Endpoint - Primary Analysis - Leuk Corr Sci - Comprehensive
Prognostic Utility of the European LeukemiaNet (ELN) Genetic-Risk Classification in Adults with De Novo Acute Myeloid Leukemia (AML): A Study of 1,550 Patients (Pts) Mrozek, K. , Marcucci, G. , Maharry, K. , Nicolet, D. , Becker, H. ... - - Blood - 2011 Abstract - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - C8525 , CALGB-10201 , CALGB-19808 , CALGB-20202 , CALGB-8461 , CALGB-8923 , CALGB-9420 , CALGB-9621 , CALGB-9665 , CALGB-9720
Central review of cytogenetics is necessary for cooperative group correlative and clinical studies of adult acute leukemia: The Cancer and Leukemia Group B experience Mrózek, Krzysztof , Carroll, Andrew J. , Maharry, Kati ... - - Int. J. Oncol. - 2008 Manuscript - No-Endpoint Endpoint - Comprehensive Analysis - Leuk Corr Sci - CALGB-8461
Molecular landscape and clinical features of acute myeloid leukemia (AML) with complex karyotype (CK) CALGB 20202 and 8461 (Alliance) Mrózek, Krzysztof , Eisfeld, Ann-Kathrin , Kohlschmidt, Jessica ... - ASH - Blood - 2017 Abstract - Secondary-not-in-original Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-20202 , CALGB-8461
Complex karyotype in de novo acute myeloid leukemia: typical and atypical subtypes differ molecularly and clinically Mrózek, Krzysztof , Eisfeld, Ann-Kathrin , Kohlschmidt, Jessica ... - - Leukemia - 2019 Manuscript - Secondary-not-in-original Endpoint - Primary Analysis - Leuk Corr Sci - C8461 , C9665 , CALGB-20202
Prognostic Significance of the European LeukemiaNet Standardized System for Reporting Cytogenetic and Molecular Alterations in Adults With Acute Myeloid Leukemia Mrózek, Krzysztof , Marcucci, Guido , Nicolet, Deedra ... - - J. Clin. Oncol. - 2012 Manuscript - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-10201 , CALGB-19808 , CALGB-8461 , CALGB-8525 , CALGB-8923 , CALGB-9420 , CALGB-9621 , CALGB-9720
Clinical relevance of mutations and gene-expression changes in adult acute myeloid leukemia with normal cytogenetics: are we ready for a prognostically prioritized molecular classification? Mrózek, Krzysztof , Marcucci, Guido , Paschka, Peter ... - - Blood - 2007 Manuscript - No-Endpoint Endpoint - Other Analysis - Leuk Corr Sci -
Patients With Acute Myeloid Leukemia and RAS Mutations Benefit Most From Postremission High-Dose Cytarabine: A Cancer and Leukemia Group B Study Neubauer, Andreas , Maharry, Kati , Mrózek, Krzysztof ... - - J Clin Oncol - 2008 Manuscript - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - C8525 , C8765 , CALGB-8461 , CALGB-9665
FTY720, a new and alternative strategy for treating blast crisis CML and Ph1 ALL patients Neviani, P. , Santhanam, R. , Oaks, J. , Eiring, A. , Notari, M. ... - AACR - AACR Annual Meeting - 2007 Abstract - Secondary-not-in-original Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-8461 , CALGB-9665
FTY720, a new alternative for treating blast crisis chronic myelogenous leukemia and Philadelphia chromosome–positive acute lymphocytic leukemia Neviani, Paolo , Santhanam, Ramasamy , Oaks, Joshua J. ... - - J Clin Invest - 2007 Manuscript - Secondary-not-in-original Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-8461 , CALGB-9665
High expression of DNMT3B negatively impacts on clinical outcome of older patients (pts) with primary cytogenetically normal (CN) acute myeloid leukemia (AML) [CALGB 20202 (Alliance)]. Niederwieser, C. , Kohlschmidt, J. , Maharry, K. , Mrózek, K. ... - EHA - European Hematology Association Congress - 2013 Abstract - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-20202
Prognostic and biologic significance of DNMT3B expression in older patients with cytogenetically normal primary acute myeloid leukemia Niederwieser, Christian , Kohlschmidt, Jessica , Volinia, Stefano ... - - Leukemia - 2015 Manuscript - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - C8461 , C9665 , CALGB-10201 , CALGB-20202 , CALGB-8525 , CALGB-8923 , CALGB-9420 , CALGB-9720
Chromosome abnormalities at onset of complete remission are associated with worse outcome in patients with acute myeloid leukemia and an abnormal karyotype at diagnosis: CALGB 8461 (Alliance) Niederwieser, Christian , Nicolet, Deedra , Carroll, Andrew J. ... - - Haematologica - 2016 Manuscript - Secondary-not-in-original Endpoint - Meta-Analysis Analysis - Leuk Corr Sci - CALGB-10201 , CALGB-10502 , CALGB-10503 , CALGB-10603 , CALGB-10801 , CALGB-11002 , CALGB-19808 , CALGB-8461 , CALGB-8525 , CALGB-8923 , CALGB-9022 , CALGB-9621 , CALGB-9720
Differential Clinical Impact Of Gene Mutations and Their Combinations In Primary Cytogenetically Normal Acute Myeloid Leukemia (CN-AML) Papaioannou, Dimitrios , Maharry, Kati , Mrózek, Krzysztof ... - ASH - Blood - 2013 Abstract - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-20202 , CALGB-9665 , CALGB-8461
Prognostic and Biologic Relevance of Clinically Applicable Long Non-Coding RNA Profiling in Older Patients with Cytogenetically Normal Acute Myeloid Leukemia Papaioannou, Dimitrios , Nicolet, Deedra , Ozer, Hatice G. ... - - Mol. Cancer Ther. - 2019 Manuscript - Secondary-not-in-original Endpoint - Comprehensive Analysis - Leuk Corr Sci - C8525 , C8621 , C9720 , CALGB-10201 , CALGB-10502 , CALGB-10801 , CALGB-11001 , CALGB-8923
Prognostic and biologic significance of long non-coding RNA (lncRNA) profiling in cytogenetically abnormal acute myeloid leukemia (CA-AML) Papaioannou, Dimitrios , Nicolet, Deedra , Rong-Mullins, Xiaoqing ... - ASH - Blood - 2018 Abstract - Secondary-not-in-original Endpoint - Primary Analysis - Leuk Corr Sci - C8461 , C9665 , CALGB-20202
Prognostic and biologic significance of long non-coding RNA profiling in younger adults with cytogenetically normal acute myeloid leukemia Papaioannou, Dimitrios , Nicolet, Deedra , Volinia, Stefano ... - - Haematologica - 2017 Manuscript - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-10503 , CALGB-10603 , CALGB-19808 , CALGB-20202 , CALGB-8461 , CALGB-8525 , CALGB-9022 , CALGB-9222 , CALGB-9621 , CALGB-9665
Long non-coding RNA profiling provides important prognostic information and biologic insights in younger patients (pts) with cytogenetically normal acute myeloid leukemia (CN-AML) (Alliance) CALGB 8461, 9665, and 20202. Papaioannou, Dimitrios , Nicoleta, Deedra , Volinia, Stefano ... - EHA - - 2016 Abstract - Secondary Endpoint - Comprehensive Analysis - Leuk Corr Sci - CALGB-20202 , CALGB-8461 , CALGB-9665
Recurrent Genetic Variants of Long Non-Coding RNAs Independently Associate with Clinical Outcome of Younger Adults with Cytogenetically Normal Acute Myeloid Leukemia (ALLIANCE/CALGB 8461, 9665, 20202) Papaioannou, Dimitrios , Ozer, Gulcin H. , Nicolet, Deedra ... - ASH - Blood - 2017 Abstract - Secondary-not-in-original Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-20202 , CALGB-8461 , CALGB-9665
Prognostic and biological significance of the proangiogenic factor EGFL7 in acute myeloid leukemia Papaioannou, Dimitrios , Shen, Changxian , Nicolet, Deedra ... - - Proc. Natl. Acad. Sci. U.S.A - 2017 Manuscript - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-10201 , CALGB-10503 , CALGB-10603 , CALGB-19808 , CALGB-20202 , CALGB-8461 , CALGB-8525 , CALGB-8923 , CALGB-9022 , CALGB-9120 , CALGB-9222 , CALGB-9420 , CALGB-9665 , CALGB-9720
Prognostic and biologic significance of circular RNA profiling in younger adult patients with cytogenetically normal acute myeloid leukemia (CN-AML) (CALGB/Alliance 8461, 9665, 20202) Papaioannou, Dimitrios , Volinia, Stefano , Nicolet, Deedra ... - EHA - - 2018 Abstract - Secondary-not-in-original Endpoint - Comprehensive Analysis - Leuk Corr Sci - CALGB-20202 , CALGB-8461 , CALGB-9665
Prognostic impact of NPM1 mutations in cytogenetically normal (CN) acute myeloid leukemia (AML) is adversely affected by high expression of the ERG gene: A Cancer and Leukemia Group B (CALGB) study Paschka, P. , Marcucci, G. , Maharry, K. S. , Whitman, S. P. ... - EHA - Haematol-Hematol J - 2007 Abstract - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-19808 , CALGB-20502 , CALGB-8461 , CALGB-9621 , CALGB-9665
Wilms Tumor 1 (WT1) Gene Mutations Predict Poor Outcome in Adults with Cytogenetically Normal (CN) Acute Myeloid Leukemia (AML): A Cancer and Leukemia Group B (CALGB) Study Paschka, P. , Marcucci, G. , Ruppert, A. S. , Mrozek, K. ... - - Blood - 2007 Abstract - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-19808 , CALGB-20502 , CALGB-8461 , CALGB-9621 , CALGB-9665
Outcome prediction in adult core binding factor (CBF) acute myeloid leukemia (AML) with gene expression profiling: A Cancer and Leukemia Group B (CALGB) study Paschka, P. , Radmacher, M. D. , Marcucci, G. , Ruppert, A. S. ... - ASCO - J. Clin. Oncol. - 2007 Abstract - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - C8525 , C9022 , CALGB-19808 , CALGB-8461 , CALGB-9222 , CALGB-9621 , CALGB-9665
Wilms’ Tumor 1 Gene Mutations Independently Predict Poor Outcome in Adults With Cytogenetically Normal Acute Myeloid Leukemia: A Cancer and Leukemia Group B Study Paschka, Peter , Marcucci, Guido , Ruppert, Amy S. ... - - J Clin Oncol - 2008 Manuscript - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-19808 , CALGB-20502 , CALGB-8461 , CALGB-9621 , CALGB-9665
Multiplexed Digital Quantification of mRNA Abundance: a Highly Reproducible, PCR-independent Assessment of BAALC, ERG, and MN1 mRNA Levels in Acute Myeloid Leukemia (AML) Bone Marrow (BM) and Peripheral Blood (PB) Samples Payton, J. E. , Marcucci, G. , Radmacher, M. D. , Maharry, K. ... - ASH - ASH Annual Meeting Abstracts - 2009 Abstract - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - C9665 , C8461
High throughput digital quantification of mRNA abundance in primary human acute myeloid leukemia samples Payton, Jacqueline E. , Grieselhuber, Nicole R. , Chang, Li-Wei ... - - J Clin Invest - 2009 Manuscript - Secondary-not-in-original Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-8461 , CALGB-9665
MicroRNA (miR) expression signatures in molecular subsets of cytogenetically normal (CN) acute myeloid leukemia (AML): A Cancer and Leukemia Group B (CALGB) study Radmacher, M. D. , Marcucci, G. , Paschka, P. , Vukosavljevic, T. ... - - J. Clin. Oncol. - 2007 Abstract - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-19808 , CALGB-20502 , CALGB-8461 , CALGB-9621 , CALGB-9665
Higher MN1 expression is an unfavorable prognosticator in older patients (Pts) with cytogenetically normal acute myeloid leukemia (CN-AML): A CALGB study Schwind, S. , Marcucci, G. , Holland, K. B. , Mrózek, K. ... - AACR - AACR Annual Meeting - 2010 Abstract - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - C20502 , C9665 , C8461 , C9621 , C19808
MicroRNA 181a (miR-181a) expression as a prognosticator in cytogenetically normal acute myeloid leukemia (CN AML) Schwind, S. , Marcucci, G. , Maharry, K. S. , Radmacher, M. D. ... - - J. Clin. Oncol. - 2009 Abstract - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - C9621 , CALGB-19808
Aberrant Gene Expression of BAALC and ERG in Older >= 60 Years (y) De Novo Cytogenetically Normal Acute Myeloid Leukemia (CN-AML): A Cancer and Leukemia Group B (CALGB) Study Schwind, S. , Marcucci, G. , Maharry, K. , Mrozek, K. ... - - Blood - 2009 Abstract - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-10201 , CALGB-20202 , CALGB-8461 , CALGB-9720
inv(16)/t(16;16) acute myeloid leukemia with non–type A CBFB-MYH11 fusions associate with distinct clinical and genetic features and lack KIT mutations Schwind, Sebastian , Edwards, Colin G. , Nicolet, Deedra ... - - Blood - 2013 Manuscript - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-8461 , CALGB-8525 , CALGB-8821 , CALGB-8923 , CALGB-9022 , CALGB-9120 , CALGB-9222 , CALGB-9621 , CALGB-9720 , CALGB-19808 , CALGB-10201 , CALGB-10502 , CALGB-10503 , CALGB-10603
Prognostic Significance of Expression of a Single MicroRNA, miR-181a, in Cytogenetically Normal Acute Myeloid Leukemia: A Cancer and Leukemia Group B Study Schwind, Sebastian , Maharry, Kati , Radmacher, Michael D. ... - - J Clin Oncol - 2010 Manuscript - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-19808 , CALGB-20202 , CALGB-20502 , CALGB-8461 , CALGB-9621 , CALGB-9665
Low expression of MN1 associates with better treatment response in older patients with de novo cytogenetically normal acute myeloid leukemia Schwind, Sebastian , Marcucci, Guido , Kohlschmidt, Jessica ... - - Blood - 2011 Manuscript - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - C8525 , CALGB-10201 , CALGB-20202 , CALGB-8461 , CALGB-8923 , CALGB-9420 , CALGB-9665 , CALGB-9720
BAALC and ERG expression levels are associated with outcome and distinct gene and microRNA expression profiles in older patients with de novo cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study Schwind, Sebastian , Marcucci, Guido , Maharry, Kati ... - - Blood - 2010 Manuscript - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - C8525 , CALGB-10201 , CALGB-20202 , CALGB-8923 , CALGB-9420 , CALGB-9720
Prognostic significance of initial clinical and molecular genetic features of acute promyelocytic leukemia (APL): Results from the North American Intergroup Trial, C9710 Stock, W. , Moser, B. K. , Powell, B. L. , Appelbaum, F. , Tallman, M. ... - ASCO - J. Clin. Oncol. - 2007 Abstract - Secondary-not-in-original Endpoint - Primary Analysis - Leuk Corr Sci - C9710 , CALGB-8461 , CALGB-9665
High incidence of FLT3 mutations in adults with Acute Promyelocytic Leukemia (APL): Correlation with diagnostic features and treatment outcome (CALGB 9710) Stock, W. , Najib, K. , Moser, B. K. , Holowka, N. , Powell, B. L. ... - - J. Clin. Oncol. - 2008 Abstract - Secondary-not-in-original Endpoint - Primary Analysis - Leuk Corr Sci - C9710 , CALGB-9665
The high prevalence of FLT3-ITD mutations is associated with the poor outcome in adult patients with t(6;9)(p23;q34) positive AML - Results of an international metaanalysis Thiede, C. , Bloomfield, C. D. , Lo Coco, F. , Frohling, S. ... - ASH - Blood - 2007 Abstract - Secondary-not-in-original Endpoint - Comprehensive Analysis - Leuk Corr Sci - CALGB-19808 , CALGB-8461 , CALGB-9621 , CALGB-9665
The high prevalence of FLT3-ITD mutations is associated with the poor outcome in adult patients with t(6;9)(p23;q34) positive AML: Results of an international metaanalysis Thiede, C. , Bloomfield, C. D. , Lo Coco, F. , Frohling, S. ... - - Onkologie - 2007 Abstract - Secondary-not-in-original Endpoint - Comprehensive Analysis - Leuk Corr Sci - CALGB-8461 , CALGB-9665
Somatic mutations and germline sequence variants in the expressed tyrosine kinase genes of patients with de novo acute myeloid leukemia Tomasson, Michael H. , Xiang, Zhifu , Walgren, Richard , Zhao, Yu ... - - Blood - 2008 Manuscript - Secondary-not-in-original Endpoint - Meta-Analysis Analysis - Leuk Corr Sci - CALGB-19808 , CALGB-9621 , CALGB-9665
New Recurrent Balanced Translocations in Acute Myeloid Leukemia and Myelodysplastic Syndromes: Cancer and Leukemia Group B (CALGB) 8461 Walker, A. , Mrózek, K. , Kohlschmidt, J. , Rao, K. W. ... - - Genes Chromosomes Cancer - 2013 Manuscript - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-8461
No evidence for microsatellite instability in acute myeloid leukemia Walker, Christopher J. , Eisfeld, Ann-Kathrin , Genutis, Luke K. ... - - Leukemia - 2017 Manuscript - Secondary-not-in-original Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-20202 , CALGB-8461 , CALGB-9665
Uniparental Disomies (UPD) of Chromosome 13q Is Associated with Shorter Disease-Free Survival in Adult Patients (Pts) with De Novo Cytogenetically Normal Acute Myeloid Leukemia (CN-AML) Walker, Christopher J. , Eisfeld, Ann-Kathrin , Kohlschmidt, Jessica ... - ASH - Blood - 2018 Abstract - Secondary-not-in-original Endpoint - Primary Analysis - Leuk Corr Sci - C8461 , CALGB-20202
Genetic Characterization and Prognostic Relevance of Acquired Uniparental Disomies in Cytogenetically Normal Acute Myeloid Leukemia Walker, Christopher J. , Kohlschmidt, Jessica , Eisfeld, Ann-Kathrin ... - - Clin. Cancer Res. - 2019 Manuscript - Secondary-not-in-original Endpoint - Meta-Analysis Analysis - Leuk Corr Sci - C8721 , CALGB-10201 , CALGB-10502 , CALGB-10503 , CALGB-10603 , CALGB-19808 , CALGB-20202 , CALGB-8461 , CALGB-8525 , CALGB-8821 , CALGB-8923 , CALGB-9022 , CALGB-9222 , CALGB-9420 , CALGB-9621 , CALGB-9665 , CALGB-9720
Genome-wide association study (GWAS) identifies a significant acute myeloid leukemia (AML) susceptibility locus near BICRA (Alliance) Walker, Christopher J. , Oakes, Christopher C. , Genutis, Luke K. ... - ASH - Blood - 2018 Abstract - Secondary-not-in-original Endpoint - Primary Analysis - Leuk Corr Sci - C8461 , CALGB-20202
Genome-wide association study identifies an acute myeloid leukemia susceptibility locus near BICRA Walker, Christopher J. , Oakes, Christopher C. , Genutis, Luke K. ... - - Leukemia - 2019 Manuscript - Secondary-not-in-original Endpoint - Primary Analysis - Leuk Corr Sci - C8461 , C9665 , CALGB-20202
High resolution array-based CGH and SNP studies of AML genomes Walter, M. J. , Ries, R. , Li, X. , Shannon, W. , Payton, J. ... - ASH - Blood - 2007 Abstract - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-8461 , CALGB-9665
Acquired copy number alterations in adult acute myeloid leukemia genomes Walter, Matthew J. , Payton, Jacqueline E. , Ries, Rhonda E. ... - - Proc Natl Acad Sci U S A - 2009 Manuscript - Secondary Endpoint - Meta-Analysis Analysis - Leuk Corr Sci - Comprehensive
Intensive induction is effective in selected octogenarian acute myeloid leukemia patients: prognostic significance of karyotype and selected molecular markers used in the European LeukemiaNet classification Wetzler, Meir , Mrózek, Krzysztof , Kohlschmidt, Jessica ... - - Haematologica - 2014 Manuscript - Secondary-not-in-original Endpoint - Primary Analysis - Leuk Corr Sci - C8221 , C8525 , C9720 , CALGB-10201 , CALGB-8923
Effective asparagine depletion with pegylated asparaginase results in improved outcomes in adult acute lymphoblastic leukemia: Cancer and Leukemia Group B Study 9511 Wetzler, Meir , Sanford, Ben L. , Kurtzberg, Joanne ... - - Blood - 2007 Manuscript - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-8461 , CALGB-9511
Adverse Prognostic Impact of FLT3 Internal Tandem Duplication (ITD) Is Age-Associated in Older >= 60 Years (Y) De Novo cytogenetically Normal Acute Myeloid Leukemia (CN-AML) Patients (Pts): a Cancer and Leukemia Group B (CALGB) Study Whitman, S. P. , Maharry, K. , Radmacher, M. D. , Mrozek, K. ... - - Blood - 2009 Abstract - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-10201 , CALGB-20202 , CALGB-8461 , CALGB-9720
Improved clinical outcome of cytogenetically normal acute myeloid leukemia patients with the MLL partial tandem duplication: A Cancer and Leukemia Group B (CALGB) study Whitman, S. P. , Ruppert, A. S. , Marcucci, G. , Mrozek, K. A. ... - - Cancer Res. - 2007 Abstract - Secondary-not-in-original Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-19808 , CALGB-20502 , CALGB-8461 , CALGB-9621 , CALGB-9665 , CALGB-9769
FLT3 D835/I836 mutations predict worse disease-free survival (DFS) in younger adults with cytogenetically normal acute myeloid leukemia (CN AML) without FLT3 internal tandem duplications (ITD): A Cancer and Leukemia Group B (CALGB) study Whitman, S. P. , Ruppert, A. S. , Radmacher, M. D. , Mrozek, K. A. ... - - J. Clin. Oncol. - 2007 Abstract - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-19808 , CALGB-20502 , CALGB-8461 , CALGB-9621 , CALGB-9665
Adverse Prognostic Impact of GAS6 Expression in De Novo Cytogenetically Normal Acute Myeloid Leukemia (CN-AML) (CALGB 8461, 9665, 20202; Alliance) Whitman, S. , Kohlschmidt, J. , Maharry, K. , Nicolet, D. ... - - Blood - 2012 Abstract - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-8461 , CALGB-9665 , CALGB-20202
The MLL partial tandem duplication in adults aged 60 years and older with de novo cytogenetically normal acute myeloid leukemia Whitman, SP , Caligiuri, MA , Maharry, K , Radmacher, MD ... - - Leukemia - 2012 Manuscript - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-10201 , CALGB-8525 , CALGB-8923 , CALGB-9420 , CALGB-9720
DNA hypermethylation and epigenetic silencing of the tumor suppressor gene, SLC5A8, in acute myeloid leukemia with the MLL partial tandem duplication Whitman, Susan P. , Hackanson, Björn , Liyanarachchi, Sandya ... - - Blood - 2008 Manuscript - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-20502 , CALGB-9665 , CALGB-9769
GAS6 expression identifies high-risk adult AML patients: potential implications for therapy Whitman, Susan P. , Kohlschmidt, Jessica , Maharry, Kati ... - - Leukemia - 2014 Manuscript - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-8525 , CALGB-8923 , CALGB-9420 , CALGB-9621 , CALGB-9720 , CALGB-10201 , CALGB-19808
FLT3 internal tandem duplication associates with adverse outcome and gene- and microRNA-expression signatures in patients 60 years of age or older with primary cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study Whitman, Susan P. , Maharry, Kati , Radmacher, Michael D. ... - - Blood - 2010 Manuscript - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - C8461 , C8525 , CALGB-10201 , CALGB-8923 , CALGB-9420 , CALGB-9720
Long-term disease-free survivors with cytogenetically normal acute myeloid leukemia and MLL partial tandem duplication: a Cancer and Leukemia Group B study Whitman, Susan P. , Ruppert, Amy S. , Marcucci, Guido ... - - Blood - 2007 Manuscript - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-19808 , CALGB-20502 , CALGB-8461 , CALGB-9621 , CALGB-9665 , CALGB-9769
FLT3 D835/I836 mutations are associated with poor disease-free survival and a distinct gene-expression signature among younger adults with de novo cytogenetically normal acute myeloid leukemia lacking FLT3 internal tandem duplications Whitman, Susan P. , Ruppert, Amy S. , Radmacher, Michael D. ... - - Blood - 2008 Manuscript - Secondary Endpoint - Primary Analysis - Leuk Corr Sci - CALGB-19808 , CALGB-20502 , CALGB-8461 , CALGB-9621 , CALGB-9665
