Increased Expression of Macrophage Migration Inhibitory Factor (MIF) Receptor CD74 Is Associated with Inferior Outcome in Younger Patients (Pts) with Cytogenetically Normal Acute Myeloid Leukemia (CN-AML): a Cancer and Leukemia Group B (CALGB) Study Attar, E. C. , Maharry, K. , Mrozek, K. , Radmacher, M. D. ... - ASH - Blood - 2009 Abstract - Secondary - Primary - Leuk Corr Sci - CALGB-10502 , CALGB-20202 , CALGB-20502 , CALGB-8461
Sole Trisomy 8 In Patients (pts) with De Novo Acute Myeloid Leukemia (AML) Is Associated with Age-Independent Poor Outcome That Is Modified by Molecular Markers and with Unique Gene- and Microrna (miR)-Signatures: a Cancer and Leukemia Group B (CALGB) Study Becker, H. , Maharry, K. , Radmacher, M. D. , Margeson, D. ... - - Blood - 2010 Abstract - Secondary - Primary - Leuk Corr Sci - C8525 , CALGB-10201 , CALGB-19808 , CALGB-20202 , CALGB-20502 , CALGB-8461 , CALGB-8923 , CALGB-9420 , CALGB-9621 , CALGB-9665 , CALGB-9720
NPM1 mutations as an independent prognosticator for older cytogenetically normal acute myeloid leukemia (CN AML) Becker, H. , Marcucci, G. , Maharry, K. , Margeson, D. ... - - J. Clin. Oncol. - 2009 Abstract - Secondary - Primary - Leuk Corr Sci - CALGB-10201 , CALGB-20202 , CALGB-8461 , CALGB-9720
Comparison of Clinical and Biologic Significance of WT1 Mutations in Populations of Older (>= 60 years y ) and Younger (< 60 y) Adult Patients (Pts) with Cytogenetically Normal (CN) De Novo Acute Myeloid Leukemia (AML): a Cancer and Leukemia Group B (CALGB) Study Becker, H. , Marcucci, G. , Maharry, K. , Radmacher, M. D. ... - - Blood - 2009 Abstract - Secondary-not-in-original - Primary - Correl Sci NOS - C8525 , CALGB-10201 , CALGB-19808 , CALGB-20202 , CALGB-20502 , CALGB-8461 , CALGB-8923 , CALGB-9420 , CALGB-9621 , CALGB-9665 , CALGB-9720
CEBPA double mutations impact favorably on the outcome of older adults with wild-type NPM1 cytogenetically normal acute myeloid leukemia and are associated with distinct gene- and microRNA-expression patterns Becker, H. , Marcucci, G. , Maharry, K. , Radmacher, M. , Wu, Y. ... - - Haematologica - 2010 Abstract - Secondary - Primary - Leuk Corr Sci - C8525 , CALGB-10201 , CALGB-20202 , CALGB-20502 , CALGB-8461 , CALGB-8923 , CALGB-9420 , CALGB-9665 , CALGB-9720
Prognostic gene mutations and distinct gene- and microRNA-expression signatures in acute myeloid leukemia with a sole trisomy 8 Becker, Heiko , Maharry, Kati , Mrózek, Krzysztof , Volinia, Stefano ... - - Leukemia - 2014 Manuscript - Secondary - Primary - Leuk Corr Sci - C8525 , CALGB-10201 , CALGB-10502 , CALGB-10503 , CALGB-10603 , CALGB-19808 , CALGB-8923 , CALGB-9022 , CALGB-9222 , CALGB-9420 , CALGB-9621 , CALGB-9720
Clinical outcome and gene- and microRNA-expression profiling according to the Wilms tumor 1 (WT1) single nucleotide polymorphism rs16754 in adult de novo cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study Becker, Heiko , Maharry, Kati , Radmacher, Michael D. ... - - Haematologica - 2011 Manuscript - Secondary - Primary - Leuk Corr Sci - C8525 , CALGB-10201 , CALGB-19808 , CALGB-20202 , CALGB-20502 , CALGB-8461 , CALGB-8923 , CALGB-9420 , CALGB-9621 , CALGB-9665 , CALGB-9720
Mutations of the Wilms tumor 1 gene (WT1) in older patients with primary cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study Becker, Heiko , Marcucci, Guido , Maharry, Kati ... - - Blood - 2010 Manuscript - Secondary - Primary - Leuk Corr Sci - C8525 , CALGB-10201 , CALGB-19808 , CALGB-20202 , CALGB-8461 , CALGB-8923 , CALGB-9420 , CALGB-9621 , CALGB-9665 , CALGB-9720
Favorable Prognostic Impact of NPM1 Mutations in Older Patients With Cytogenetically Normal De Novo Acute Myeloid Leukemia and Associated Gene- and MicroRNA-Expression Signatures: A Cancer and Leukemia Group B Study Becker, Heiko , Marcucci, Guido , Maharry, Kati ... - - J Clin Oncol - 2010 Manuscript - Secondary - Primary - Leuk Corr Sci - CALGB-10201 , CALGB-19808 , CALGB-20202 , CALGB-8461 , CALGB-9720
Heritable polymorphism predisposes to high expression of BAALC in cytogenetically normal acute myeloid leukemia (CN-AML) Eisfeld, Ann-Kathrin , Marcucci, G. , Liyanarachchi, S. , Döhner, K. ... - AACR - AACR Annual Meeting - 2012 Abstract - Secondary - Primary - Leuk Corr Sci - C9665
MiR-3151, a novel microRNA embedded in BAALC, is only weakly co-xxpressed with its host gene and independently impacts on the clinical outcome of older patients (pts) with de novo cytogenetically normal acute myeloid leukemia (CN-AML) Eisfeld, Ann-Kathrin , Marcucci, G. , Maharry, K. , Schwind, S. ... - - Blood - 2011 Abstract - Secondary - Primary - Leuk Corr Sci - C8525 , CALGB-10201 , CALGB-8923 , CALGB-9420 , CALGB-9720
Heritable polymorphism predisposes to high BAALC expression in acute myeloid leukemia Eisfeld, Ann-Kathrin , Marcucci, Guido , Liyanarachchi, Sandya ... - - Proc. Natl. Acad. Sci. U.S.A - 2012 Manuscript - Secondary - Primary - Leuk Corr Sci - CALGB-9665
miR-3151 interplays with its host gene BAALC and independently affects outcome of patients with cytogenetically normal acute myeloid leukemia Eisfeld, Ann-Kathrin , Marcucci, Guido , Maharry, Kati ... - - Blood - 2012 Manuscript - Secondary - Primary - Leuk Corr Sci - CALGB-9665
High expression of IGFBP2 is associated with chemoresistance in adult acute myeloid leukemia Kühnl, Andrea , Kaiser, Martin , Neumann, Martin , Fransecky, Lars ... - - Leuk. Res. - 2011 Manuscript - Secondary - Primary - Leuk Corr Sci - C9665 , C20202 , C9621 , C8461
High BAALC expression associates with other molecular prognostic markers, poor outcome and a distinct gene expression signature in cytogenetically normal acute myeloid leukemia (CN AML): A Cancer and Leukemia Group B (CALGB) study Langer, C. , Ruppert, A. S. , Radmacher, M. D. , Whitman, S. P. ... - - J. Clin. Oncol. - 2007 Abstract - Secondary - Primary - Leuk Corr Sci - CALGB-19808 , CALGB-20502 , CALGB-8461 , CALGB-9621 , CALGB-9665
Prognostic Importance of MN1 Transcript Levels, and Biologic Insights From MN1-Associated Gene and MicroRNA Expression Signatures in Cytogenetically Normal Acute Myeloid Leukemia: A Cancer and Leukemia Group B Study Langer, Christian , Marcucci, Guido , Holland, Kelsi B. ... - - J Clin Oncol - 2009 Manuscript - Secondary - Primary - Leuk Corr Sci - CALGB-19808 , CALGB-20502 , CALGB-8461 , CALGB-9621 , CALGB-9665
High BAALC expression associates with other molecular prognostic markers, poor outcome, and a distinct gene-expression signature in cytogenetically normal patients younger than 60 years with acute myeloid leukemia: a Cancer and Leukemia Group B (CALGB) study Langer, Christian , Radmacher, Michael D. , Ruppert, Amy S. ... - - Blood - 2008 Manuscript - Secondary - Primary - Leuk Corr Sci - CALGB-19808 , CALGB-20502 , CALGB-8461 , CALGB-9621 , CALGB-9665
Up-regulation of a HOXA-PBX3 homeobox-gene signature following down-regulation of miR-181 is associated with adverse prognosis in patients with cytogenetically abnormal AML Li, Z. , Huang, H. , Li, Y. , Jiang, X. , Chen, P. , Arnovitz, S. ... - - Blood - 2012 Manuscript - Secondary-not-in-original - Primary - Leuk Corr Sci - C9665
Activation of a Mir-181-Targeting HOXA-PBX3 Homeobox Gene Signature Is Associated with Adverse Prognosis of Cytogenetically Abnormal Acute Myeloid Leukemia Li, Z. , Huang, H. , Li, Y. , Jiang, X. , Chen, P. , Arnovitz, S. ... - ASH - ASH Annual Meeting Abstracts - 2011 Abstract - Secondary-not-in-original - Primary - Leuk Corr Sci - C9665
Identification of a 24-Gene Prognostic Signature That Improves the European LeukemiaNet Risk Classification of Acute Myeloid Leukemia: An International Collaborative Study Li, Zejuan , Herold, Tobias , He, Chunjiang , Valk, Peter J.M. ... - - J. Clin. Oncol - 2013 Manuscript - Secondary-not-in-original - Meta-Analysis - Leukemia - CALGB-19808 , CALGB-9222 , CALGB-9621 , CALGB-9710 , CALGB-9720
Sp1/NFκB/HDAC/miR-29b Regulatory Network in KIT-driven Myeloid Leukemia Liu, Shujun , Wu, Lai-Chu , Pang, Jiuxia , Santhanam, Ramasamy ... - - Cancer Cell - 2010 Manuscript - Secondary - Primary - Leuk Corr Sci - C9665
IDH1 and IDH2 gene mutations identify novel molecular subsets within de novo cytogenetically normal acute myeloid leukemia (CN-AML): A Cancer and Leukemia Group B (CALGB) Study Marcucci, G. , Maharry, K. S. , Wu, Y. , Radmacher, M. D. ... - - Haematologica - 2010 Abstract - Secondary - Primary - Leuk Corr Sci - C8525 , CALGB-10201 , CALGB-19808 , CALGB-20202 , CALGB-20502 , CALGB-8461 , CALGB-8923 , CALGB-9420 , CALGB-9621 , CALGB-9665 , CALGB-9720
Gene and microRNA (miRNA) Expression Signatures and Prognostic Significance of CEBPA Mutations in Cytogenetically Normal (CN) Acute Myeloid Leukemia (AML) with High-Risk Molecular Features: A Cancer and Leukemia Group B (CALGB) Study Marcucci, G. , Maharry, K. , Radmacher, M. D. , Mrozek, K. ... - - Blood - 2007 Abstract - Secondary - Primary - Leuk Corr Sci - CALGB-19808 , CALGB-20205 , CALGB-20502 , CALGB-8461 , CALGB-9621 , CALGB-9665
Prognostic Significance of, and Gene and MicroRNA Expression Signatures Associated With, CEBPA Mutations in Cytogenetically Normal Acute Myeloid Leukemia With High-Risk Molecular Features: A Cancer and Leukemia Group B Study Marcucci, Guido , Maharry, Kati , Radmacher, Michael D. ... - - J Clin Oncol - 2008 Manuscript - Secondary - Primary - Leuk Corr Sci - CALGB-19808 , CALGB-20502 , CALGB-8461 , CALGB-9621 , CALGB-9665
IDH1 and IDH2 Gene Mutations Identify Novel Molecular Subsets Within De Novo Cytogenetically Normal Acute Myeloid Leukemia: A Cancer and Leukemia Group B Study Marcucci, Guido , Maharry, Kati , Wu, Yue-Zhong ... - - J Clin Oncol - 2010 Manuscript - Secondary - Primary - Leuk Corr Sci - C8421 , C8525 , CALGB-10201 , CALGB-19808 , CALGB-20202 , CALGB-20502 , CALGB-8923 , CALGB-9420 , CALGB-9621 , CALGB-9665 , CALGB-9720
Age-Related Prognostic Impact of Different Types of DNMT3A Mutations in Adults With Primary Cytogenetically Normal Acute Myeloid Leukemia Marcucci, Guido , Metzeler, Klaus H. , Schwind, Sebastian ... - - J. Clin. Oncol. - 2012 Manuscript - Secondary - Primary - Leuk Corr Sci - CALGB-9621 , CALGB-19808
MicroRNA expression in cytogenetically normal acute myeloid leukemia. Marcucci, Guido , Radmacher, Michael D , Maharry, Kati ... - - N. Engl. J. Med. - 2008 Manuscript - Secondary - Primary - Leuk Corr Sci - CALGB-19808 , CALGB-20502 , CALGB-8461 , CALGB-9621 , CALGB-9665
Poor Outcome of RUNX1-Mutated (RUNX1-mut) Patients (Pts) with Primary, Cytogenetically Normal Acute Myeloid Leukemia (CN-AML) and Associated Gene- and MicroRNA (miR) Expression Signatures Mendler, J. H. , Maharry, K. , Radmacher, M. D. , Mrozek, K. ... - - Blood - 2011 Abstract - Secondary - Primary - Leuk Corr Sci - C8525 , CALGB-10201 , CALGB-19808 , CALGB-8923 , CALGB-9420 , CALGB-9621 , CALGB-9720
RUNX1 Mutations Are Associated With Poor Outcome in Younger and Older Patients With Cytogenetically Normal Acute Myeloid Leukemia and With Distinct Gene and MicroRNA Expression Signatures Mendler, Jason H. , Maharry, Kati , Radmacher, Michael D. ... - - J. Clin. Oncol. - 2012 Manuscript - Secondary - Primary - Leuk Corr Sci - C8525 , CALGB-8461 , CALGB-8923 , CALGB-9420 , CALGB-9621 , CALGB-9665 , CALGB-9720 , CALGB-10201 , CALGB-19808 , CALGB-20202
ASXL1 Mutations Identify a High-Risk Subgroup of Older Patients with Primary Cytogenetically Normal Acute Myeloid Leukemia within the European LeukemiaNet 'Favorable' Genetic Category Metzeler, K. H. , Becker, H. , Maharry, K. , Radmacher, M. D. ... - - Blood - 2011 Abstract - Secondary - Primary - Leuk Corr Sci - CALGB-20202 , CALGB-8461 , CALGB-9665
An 86-Probe Gene Expression Signature Can Predict Survival in AML with Normal Karyotype Independently of FLT3 ITD and NPM1 Mutation Status - A Collaborative Study from the AMLCG and CALGB Study Groups Metzeler, K. H. , Hummel, M. , Bloomfield, C. D. , Spiekermann, K. ... - - Blood - 2007 Abstract - Secondary - Primary - Leuk Corr Sci - CALGB-8461 , CALGB-9621 , CALGB-9665
TET2 mutations occur in over 20% of adults with de novo cytogenetically normal AML, and their prevalence increases with age: A Cancer and Leukemia Goup B study. Metzeler, K. H. , Maharry, K. , Margeson, D. , Curfman, J. ... - - Haematologica - 2010 Abstract - Secondary - Primary - Leuk Corr Sci - C8525 , CALGB-10201 , CALGB-19808 , CALGB-20202 , CALGB-20502 , CALGB-8461 , CALGB-8923 , CALGB-9420 , CALGB-9621 , CALGB-9665 , CALGB-9720
Mutations In the Tet Oncogene Family Member 2 (TET2) Gene Refine the New European LeukemiaNet Risk Classification of Primary, Cytogenetically Normal Acute Myeloid Leukemia (CN-AML) In Adults: A Cancer and Leukemia Group B (CALGB) Study Metzeler, K. H. , Maharry, K. , Radmacher, M. D. , Mrozek, K. ... - - Blood - 2010 Abstract - Secondary - Primary - Leuk Corr Sci - C8525 , C8641 , CALGB-10201 , CALGB-19808 , CALGB-20202 , CALGB-20502 , CALGB-8923 , CALGB-9420 , CALGB-9621 , CALGB-9665 , CALGB-9720
ASXL1 mutations identify a high-risk subgroup of older patients with primary cytogenetically normal AML within the ELN Favorable genetic category Metzeler, Klaus H. , Becker, Heiko , Maharry, Kati ... - - Blood - 2011 Manuscript - Secondary - Primary - Leuk Corr Sci - CALGB-20202 , CALGB-8461 , CALGB-9665
An 86-probe-set gene-expression signature predicts survival in cytogenetically normal acute myeloid leukemia Metzeler, Klaus H. , Hummel, Manuela , Bloomfield, Clara D. ... - - Blood - 2008 Manuscript - Secondary-not-in-original - Meta-Analysis - Leuk Corr Sci - CALGB-8461 , CALGB-9621 , CALGB-9665
TET2 Mutations Improve the New European LeukemiaNet Risk Classification of Acute Myeloid Leukemia: A Cancer and Leukemia Group B Study Metzeler, Klaus H. , Maharry, Kati , Radmacher, Michael D. ... - - J Clin Oncol - 2011 Manuscript - Secondary - Primary - Leuk Corr Sci - C8525 , CALGB-10201 , CALGB-19808 , CALGB-20202 , CALGB-20502 , CALGB-8461 , CALGB-8923 , CALGB-9420 , CALGB-9621 , CALGB-9665 , CALGB-9720
Outcome prediction in adult core binding factor (CBF) acute myeloid leukemia (AML) with gene expression profiling: A Cancer and Leukemia Group B (CALGB) study Paschka, P. , Radmacher, M. D. , Marcucci, G. , Ruppert, A. S. ... - ASCO - J. Clin. Oncol. - 2007 Abstract - Secondary - Primary - Leuk Corr Sci - C8525 , C9022 , CALGB-19808 , CALGB-8461 , CALGB-9222 , CALGB-9621 , CALGB-9665
Multiplexed Digital Quantification of mRNA Abundance: a Highly Reproducible, PCR-independent Assessment of BAALC, ERG, and MN1 mRNA Levels in Acute Myeloid Leukemia (AML) Bone Marrow (BM) and Peripheral Blood (PB) Samples Payton, J. E. , Marcucci, G. , Radmacher, M. D. , Maharry, K. ... - ASH - ASH Annual Meeting Abstracts - 2009 Abstract - Secondary - Primary - Leuk Corr Sci - C9665 , C8461
MicroRNA (miR) expression signatures in molecular subsets of cytogenetically normal (CN) acute myeloid leukemia (AML): A Cancer and Leukemia Group B (CALGB) study Radmacher, M. D. , Marcucci, G. , Paschka, P. , Vukosavljevic, T. ... - - J. Clin. Oncol. - 2007 Abstract - Secondary - Primary - Leuk Corr Sci - CALGB-19808 , CALGB-20502 , CALGB-8461 , CALGB-9621 , CALGB-9665
Higher MN1 expression is an unfavorable prognosticator in older patients (Pts) with cytogenetically normal acute myeloid leukemia (CN-AML): A CALGB study Schwind, S. , Marcucci, G. , Holland, K. B. , Mrózek, K. ... - AACR - AACR Annual Meeting - 2010 Abstract - Secondary - Primary - Leuk Corr Sci - C20502 , C9665 , C8461 , C9621 , C19808
MicroRNA 181a (miR-181a) expression as a prognosticator in cytogenetically normal acute myeloid leukemia (CN AML) Schwind, S. , Marcucci, G. , Maharry, K. S. , Radmacher, M. D. ... - - J. Clin. Oncol. - 2009 Abstract - Secondary - Primary - Leuk Corr Sci - C9621 , CALGB-19808
Aberrant Gene Expression of BAALC and ERG in Older >= 60 Years (y) De Novo Cytogenetically Normal Acute Myeloid Leukemia (CN-AML): A Cancer and Leukemia Group B (CALGB) Study Schwind, S. , Marcucci, G. , Maharry, K. , Mrozek, K. ... - - Blood - 2009 Abstract - Secondary - Primary - Leuk Corr Sci - CALGB-10201 , CALGB-20202 , CALGB-8461 , CALGB-9720
Prognostic Significance of Expression of a Single MicroRNA, miR-181a, in Cytogenetically Normal Acute Myeloid Leukemia: A Cancer and Leukemia Group B Study Schwind, Sebastian , Maharry, Kati , Radmacher, Michael D. ... - - J Clin Oncol - 2010 Manuscript - Secondary - Primary - Leuk Corr Sci - CALGB-19808 , CALGB-20202 , CALGB-20502 , CALGB-8461 , CALGB-9621 , CALGB-9665
Low expression of MN1 associates with better treatment response in older patients with de novo cytogenetically normal acute myeloid leukemia Schwind, Sebastian , Marcucci, Guido , Kohlschmidt, Jessica ... - - Blood - 2011 Manuscript - Secondary - Primary - Leuk Corr Sci - C8525 , CALGB-10201 , CALGB-20202 , CALGB-8461 , CALGB-8923 , CALGB-9420 , CALGB-9665 , CALGB-9720
BAALC and ERG expression levels are associated with outcome and distinct gene and microRNA expression profiles in older patients with de novo cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study Schwind, Sebastian , Marcucci, Guido , Maharry, Kati ... - - Blood - 2010 Manuscript - Secondary - Primary - Leuk Corr Sci - C8525 , CALGB-10201 , CALGB-20202 , CALGB-8923 , CALGB-9420 , CALGB-9720
Adverse Prognostic Impact of FLT3 Internal Tandem Duplication (ITD) Is Age-Associated in Older >= 60 Years (Y) De Novo cytogenetically Normal Acute Myeloid Leukemia (CN-AML) Patients (Pts): a Cancer and Leukemia Group B (CALGB) Study Whitman, S. P. , Maharry, K. , Radmacher, M. D. , Mrozek, K. ... - - Blood - 2009 Abstract - Secondary - Primary - Leuk Corr Sci - CALGB-10201 , CALGB-20202 , CALGB-8461 , CALGB-9720
FLT3 D835/I836 mutations predict worse disease-free survival (DFS) in younger adults with cytogenetically normal acute myeloid leukemia (CN AML) without FLT3 internal tandem duplications (ITD): A Cancer and Leukemia Group B (CALGB) study Whitman, S. P. , Ruppert, A. S. , Radmacher, M. D. , Mrozek, K. A. ... - - J. Clin. Oncol. - 2007 Abstract - Secondary - Primary - Leuk Corr Sci - CALGB-19808 , CALGB-20502 , CALGB-8461 , CALGB-9621 , CALGB-9665
The MLL partial tandem duplication in adults aged 60 years and older with de novo cytogenetically normal acute myeloid leukemia Whitman, SP , Caligiuri, MA , Maharry, K , Radmacher, MD ... - - Leukemia - 2012 Manuscript - Secondary - Primary - Leuk Corr Sci - CALGB-10201 , CALGB-8525 , CALGB-8923 , CALGB-9420 , CALGB-9720
FLT3 internal tandem duplication associates with adverse outcome and gene- and microRNA-expression signatures in patients 60 years of age or older with primary cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study Whitman, Susan P. , Maharry, Kati , Radmacher, Michael D. ... - - Blood - 2010 Manuscript - Secondary - Primary - Leuk Corr Sci - C8461 , C8525 , CALGB-10201 , CALGB-8923 , CALGB-9420 , CALGB-9720
FLT3 D835/I836 mutations are associated with poor disease-free survival and a distinct gene-expression signature among younger adults with de novo cytogenetically normal acute myeloid leukemia lacking FLT3 internal tandem duplications Whitman, Susan P. , Ruppert, Amy S. , Radmacher, Michael D. ... - - Blood - 2008 Manuscript - Secondary - Primary - Leuk Corr Sci - CALGB-19808 , CALGB-20502 , CALGB-8461 , CALGB-9621 , CALGB-9665