Expression and polymorphism (rs4880) of mitochondrial superoxide dismutase (SOD2) and asparaginase induced hepatotoxicity in adult patients with acute lymphoblastic leukemia Alachkar, Houda , Fulton, Noreen , Sanford, Ben , Malnassy, Greg ... - - Pharmacogenomics J. - 2017 Manuscript - Secondary - Primary - Leuk Corr Sci - CALGB-10102
SPARC promotes leukemic cell growth and predicts acute myeloid leukemia outcome Alachkar, Houda , Santhanam, Ramasamy , Maharry, Kati ... - - J. Clin. Invest - 2014 Manuscript - Secondary - Primary - Leuk Corr Sci - CALGB-19808 , CALGB-9621
A phase II study of bortezomib added to standard daunorubicin and cytarabine during induction therapy and to intermediate-dose cytarabine (Int-DAC) for consolidation in patients with previously untreated acute myeloid leukemia (AML) age 60-75 years: CALGB study 10502. Attar, E. C. , Johnson, J. L. , Amrein, P. C. , Lozanski, G. ... - - J. Clin. Oncol. - 2012 Abstract - Primary - Primary - Leukemia - CALGB-10502
Increased Expression of Macrophage Migration Inhibitory Factor (MIF) Receptor CD74 Is Associated with Inferior Outcome in Younger Patients (Pts) with Cytogenetically Normal Acute Myeloid Leukemia (CN-AML): a Cancer and Leukemia Group B (CALGB) Study Attar, E. C. , Maharry, K. , Mrozek, K. , Radmacher, M. D. ... - ASH - Blood - 2009 Abstract - Secondary - Primary - Leuk Corr Sci - CALGB-10502 , CALGB-20202 , CALGB-20502 , CALGB-8461
Bortezomib Added to Daunorubicin and Cytarabine During Induction Therapy and to Intermediate-Dose Cytarabine for Consolidation in Patients With Previously Untreated Acute Myeloid Leukemia Age 60 to 75 Years: CALGB (Alliance) Study 10502 Attar, Eyal C. , Johnson, Jeffrey L. , Amrein, Philip C. ... - - J. Clin. Oncol. - 2013 Manuscript - Primary - Primary - Leukemia - CALGB-10502
Treatment of older patients with de novo acute myeloid leukemia (AML) with one or more postremission chemotherapy courses: Analysis of four CALGB studies Baer, M. R. , George, S. L. , Sanford, B. L. , Stone, R. M. ... - ASCO - J. Clin. Oncol. - 2010 Abstract - Secondary-not-in-original - Comprehensive - Leukemia - C8525 , CALGB-10201 , CALGB-8923 , CALGB-9720
Sole Trisomy 8 In Patients (pts) with De Novo Acute Myeloid Leukemia (AML) Is Associated with Age-Independent Poor Outcome That Is Modified by Molecular Markers and with Unique Gene- and Microrna (miR)-Signatures: a Cancer and Leukemia Group B (CALGB) Study Becker, H. , Maharry, K. , Radmacher, M. D. , Margeson, D. ... - - Blood - 2010 Abstract - Secondary - Primary - Leuk Corr Sci - C8525 , CALGB-10201 , CALGB-19808 , CALGB-20202 , CALGB-20502 , CALGB-8461 , CALGB-8923 , CALGB-9420 , CALGB-9621 , CALGB-9665 , CALGB-9720
NPM1 mutations as an independent prognosticator for older cytogenetically normal acute myeloid leukemia (CN AML) Becker, H. , Marcucci, G. , Maharry, K. , Margeson, D. ... - - J. Clin. Oncol. - 2009 Abstract - Secondary - Primary - Leuk Corr Sci - CALGB-10201 , CALGB-20202 , CALGB-8461 , CALGB-9720
Comparison of Clinical and Biologic Significance of WT1 Mutations in Populations of Older (>= 60 years y ) and Younger (< 60 y) Adult Patients (Pts) with Cytogenetically Normal (CN) De Novo Acute Myeloid Leukemia (AML): a Cancer and Leukemia Group B (CALGB) Study Becker, H. , Marcucci, G. , Maharry, K. , Radmacher, M. D. ... - - Blood - 2009 Abstract - Secondary-not-in-original - Primary - Correl Sci NOS - C8525 , CALGB-10201 , CALGB-19808 , CALGB-20202 , CALGB-20502 , CALGB-8461 , CALGB-8923 , CALGB-9420 , CALGB-9621 , CALGB-9665 , CALGB-9720
CEBPA double mutations impact favorably on the outcome of older adults with wild-type NPM1 cytogenetically normal acute myeloid leukemia and are associated with distinct gene- and microRNA-expression patterns Becker, H. , Marcucci, G. , Maharry, K. , Radmacher, M. , Wu, Y. ... - - Haematologica - 2010 Abstract - Secondary - Primary - Leuk Corr Sci - C8525 , CALGB-10201 , CALGB-20202 , CALGB-20502 , CALGB-8461 , CALGB-8923 , CALGB-9420 , CALGB-9665 , CALGB-9720
Prognostic gene mutations and distinct gene- and microRNA-expression signatures in acute myeloid leukemia with a sole trisomy 8 Becker, Heiko , Maharry, Kati , Mrózek, Krzysztof , Volinia, Stefano ... - - Leukemia - 2014 Manuscript - Secondary - Primary - Leuk Corr Sci - C8525 , CALGB-10201 , CALGB-10502 , CALGB-10503 , CALGB-10603 , CALGB-19808 , CALGB-8923 , CALGB-9022 , CALGB-9222 , CALGB-9420 , CALGB-9621 , CALGB-9720
Clinical outcome and gene- and microRNA-expression profiling according to the Wilms tumor 1 (WT1) single nucleotide polymorphism rs16754 in adult de novo cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study Becker, Heiko , Maharry, Kati , Radmacher, Michael D. ... - - Haematologica - 2011 Manuscript - Secondary - Primary - Leuk Corr Sci - C8525 , CALGB-10201 , CALGB-19808 , CALGB-20202 , CALGB-20502 , CALGB-8461 , CALGB-8923 , CALGB-9420 , CALGB-9621 , CALGB-9665 , CALGB-9720
Mutations of the Wilms tumor 1 gene (WT1) in older patients with primary cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study Becker, Heiko , Marcucci, Guido , Maharry, Kati ... - - Blood - 2010 Manuscript - Secondary - Primary - Leuk Corr Sci - C8525 , CALGB-10201 , CALGB-19808 , CALGB-20202 , CALGB-8461 , CALGB-8923 , CALGB-9420 , CALGB-9621 , CALGB-9665 , CALGB-9720
Favorable Prognostic Impact of NPM1 Mutations in Older Patients With Cytogenetically Normal De Novo Acute Myeloid Leukemia and Associated Gene- and MicroRNA-Expression Signatures: A Cancer and Leukemia Group B Study Becker, Heiko , Marcucci, Guido , Maharry, Kati ... - - J Clin Oncol - 2010 Manuscript - Secondary - Primary - Leuk Corr Sci - CALGB-10201 , CALGB-19808 , CALGB-20202 , CALGB-8461 , CALGB-9720
Challenges for conducting clinical trials evaluating maintenance chemotherapy in acute myeloid leukemia (AML): a Cancer and Leukemia Group B (CALGB) study Blum, W. , Donohue, K. , Marcucci, G. , Deangelo, D. J. , Uy, G. L. ... - ASH - Blood - 2010 Abstract - No-Endpoint - Comprehensive - Leukemia - CALGB-10503
Maintenance Therapy with Decitabine in Younger Adults with Acute Myeloid Leukemia (AML) in First Remission: A Phase II Cancer and Leukemia Group B Study (CALGB 10503, Alliance) Blum, W. , Sanford, B. , Klisovic, R. B. , Deangelo, D. J. , Uy, G. ... - ASH - Blood - 2012 Abstract - Primary - Primary - Leukemia - CALGB-10503
Maintenance therapy with decitabine in younger adults with acute myeloid leukemia in first remission: a phase 2 Cancer and Leukemia Group B study (CALGB 10503) Blum, William , Sanford, Ben L. , Klisovic, Rebecca ... - - Leukemia - 2017 Manuscript - Primary - Primary - Leukemia - CALGB-10503
Quantitative DNA methylation analysis identifies a single CpG dinucleotide important for ZAP-70 expression and predictive of prognosis in chronic lymphocytic leukemia Claus, R. , Lucas, D. M. , Stilgenbauer, S. , Ruppert, A. S. , Yu, L. ... - - J. Clin. Oncol. - 2012 Manuscript - Secondary - Primary - Leuk Corr Sci - C9712
Acute Myeloid Leukemia (AML) with 9q aberrations occuring within a non-complex karyotype is highly associated with CEBPA and NPM1 mutations - A joint analysis of the German-Austrian AML Study Group (AMLSG) and Cancer and Leukemia Group B (CALGB) Corbacioglu, A. , Frohling, S. , Paschka, P. , Marcucci, G. ... - ASH - Blood - 2007 Abstract - Secondary-not-in-original - Primary - Leuk Corr Sci - CALGB-19808 , CALGB-8461 , CALGB-9621 , CALGB-9665
Clinical impact of ABL1 kinase domain mutations and IKZF1 deletion in adults under age 60 with Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL): molecular analysis of CALGB (Alliance) 10001 and 9665 DeBoer, Rebecca , Koval, Gregory , Mulkey, Flora , Wetzler, Meir ... - - Leuk. Lymphoma - 2016 Manuscript - Secondary-not-in-original - Primary - Leuk Corr Sci - CALGB-10001 , C9665
Clinical impact of ABL1 kinase and IKZF1 mutations in adults with Philadelphia chromosome-positive (PH+) acute lymphoblastic leukemia (ALL): molecular analysis of CALGB 10001 and 9665 (Alliance) DeBoer, Rebecca , Mulkey, Flora , Koval, Gregory , Wetzler, Meir ... - EHA - Haematologica - 2014 Abstract - Secondary - Primary - Leuk Corr Sci - CALGB-10001 , CALGB-9665
Impact of NPM1/FLT3-ITD genotypes defined by the 2017 European LeukemiaNet in patients with acute myeloid leukemia Döhner, Konstanze , Thiede, Christian , Jahn, Nikolaus ... - - Blood - 2020 Manuscript - Secondary-not-in-original - Primary - Leuk Corr Sci - CALGB-10603
Prognostic and predictive impact of NPM1/FLT3-ITD genotypes as defined by 2017 European LeukemiaNet (ELN) risk categorization from randomized patients with acute myeloid leukemia (AML) treated within the International RATIFY Study (ALLIANCE 10603) Döhner, Konstanze , Thiede, Christian , Jahn, Nikolaus ... - EHA - HemaSphere - 2019 Abstract - Secondary-not-in-original - Primary - Leukemia - CALGB-10603
Prognostic impact of NPM1/FLT3-ITD genotypes from randomized patients treated within the RATIFY/CALGB 10603 (Alliance) Study Döhner, Konstanze , Thiede, Christian , Larson, Richard A. ... - ASH - Blood - 2017 Abstract - Secondary-not-in-original - Primary - Leukemia - CALGB-10603
Cytogenetic, Molecular and Clinical Features Associated with Rare CBFB-MYH11 Fusion Transcripts in Patients (Pts) with Acute Myeloid Leukemia (AML) and inv(16)/t(16;16) Edwards, C. G. , Maharry, K. , Mrozek, K. , Schwind, S. , Paschka, P. ... - - Blood - 2011 Abstract - Primary - Comprehensive - Leuk Corr Sci - CALGB-10503 , CALGB-19808 , CALGB-9621
Heritable polymorphism predisposes to high expression of BAALC in cytogenetically normal acute myeloid leukemia (CN-AML) Eisfeld, Ann-Kathrin , Marcucci, G. , Liyanarachchi, S. , Döhner, K. ... - AACR - AACR Annual Meeting - 2012 Abstract - Secondary - Primary - Leuk Corr Sci - C9665
MiR-3151, a novel microRNA embedded in BAALC, is only weakly co-xxpressed with its host gene and independently impacts on the clinical outcome of older patients (pts) with de novo cytogenetically normal acute myeloid leukemia (CN-AML) Eisfeld, Ann-Kathrin , Marcucci, G. , Maharry, K. , Schwind, S. ... - - Blood - 2011 Abstract - Secondary - Primary - Leuk Corr Sci - C8525 , CALGB-10201 , CALGB-8923 , CALGB-9420 , CALGB-9720
Heritable polymorphism predisposes to high BAALC expression in acute myeloid leukemia Eisfeld, Ann-Kathrin , Marcucci, Guido , Liyanarachchi, Sandya ... - - Proc. Natl. Acad. Sci. U.S.A - 2012 Manuscript - Secondary - Primary - Leuk Corr Sci - CALGB-9665
miR-3151 interplays with its host gene BAALC and independently affects outcome of patients with cytogenetically normal acute myeloid leukemia Eisfeld, Ann-Kathrin , Marcucci, Guido , Maharry, Kati ... - - Blood - 2012 Manuscript - Secondary - Primary - Leuk Corr Sci - CALGB-9665
Comparison of Reduced-Intensity Hematopoietic Cell Transplantation with Chemotherapy in Patients Aged 60–70 Years with Acute Myeloid Leukemia in First Remission Farag, Sherif S. , Maharry, Kati , Zhang, Mei-Jie , Pérez, Waleska S. ... - - Biol. Blood Marrow Transplant. - 2011 Manuscript - Secondary-not-in-original - Comprehensive - Leukemia - CALGB-9720 , CALGB-10201
Expression and prognostic impact of lncRNAs in acute myeloid leukemia Garzon, Ramiro , Volinia, Stefano , Papaioannou, Dimitrios ... - - Proc. Natl. Acad. Sci. U.S.A - 2014 Manuscript - Secondary - Primary - Leuk Corr Sci - CALGB-20202
Dual Epigenetic Control of CCAAT/Enhancer Binding Protein {alpha} (C/EBP{alpha}) Expression in Acute Myeloid Leukemia Hackanson, B. , Bennett, K. L. , Brena, R. M. , Jiang, J. ... - - Blood - 2007 Abstract - Secondary - Primary - Leuk Corr Sci - CALGB-19808 , CALGB-20502 , CALGB-8461 , CALGB-9621 , CALGB-9665
Epigenetic modification of CCAAT/enhancer binding protein alpha expression in acute myeloid leukemia. Hackanson, Björn , Bennett, Kristi L , Brena, Romulo M ... - - Cancer Res. - 2008 Manuscript - Secondary - Primary - Leuk Corr Sci - CALGB-8461 , CALGB-9665
Implications of the miR-10 family in chemotherapy response of NPM1-mutated AML Havelange, Violaine , Ranganathan, Parvathi , Geyer, Susan ... - - Blood - 2014 Manuscript - Secondary - Primary - Leuk Corr Sci - C8525 , C9720 , CALGB-10201 , CALGB-8923 , CALGB-9420
Lenalidomide-mediated enhanced translation of C/EBPα-p30 protein up-regulates expression of the antileukemic microRNA-181a in acute myeloid leukemia Hickey, Christopher J. , Schwind, Sebastian , Radomska, Hanna S. ... - - Blood - 2013 Manuscript - Secondary - Primary - Leuk Corr Sci - CALGB-9621 , CALGB-19808
Patients with chronic lymphocytic leukemia with high-risk genomic features have inferior outcome on successive Cancer and Leukemia Group B trials with alemtuzumab consolidation: subgroup analysis from CALGB 19901 and CALGB 10101 Jones, J. A. , Ruppert, A. S. , Zhao, W. , Lin, T. S. , Rai, K. ... - - Leuk. Lymphoma - 2013 Manuscript - Secondary-not-in-original - Comprehensive - Leukemia - CALGB-19901 , CALGB-10101
Alemtuzumab Consolidation Does Not Improve Outcome for CLL Patients with High Risk Genomic Features on Successive CALGB Trials Jones, J. A. , Stark, A. , Zhao, W. , Lin, T. S. , Rai, K. R. ... - - Blood - 2011 Abstract - Secondary-not-in-original - Comprehensive - Leukemia - CALGB-10101 , CALGB-19901
A variant allele of Growth Factor Independence 1 (GFI1) is associated with acute myeloid leukemia Khandanpour, C. , Thiede, C. , Valk, P. J. , Sharif-Askari, E. ... - - Blood - 2010 Manuscript - Secondary - Primary - Leuk Corr Sci - C9665 , C8461
Feasibility of geriatric assessment for older adults with acute myeloid leukemia (AML) receiving intensive chemotherapy on a cooperative group trial: CALGB 361006 (Alliance). Klepin, Heidi D. , Ritchie, Ellen K. , Sanford, Ben L. ... - ASCO - J. Clin. Oncol. - 2014 Abstract - Primary - Primary - Older Adult - CALGB-361006
Geriatric assessment among older adults receiving intensive therapy for acute myeloid leukemia: Report of CALGB 361006 (Alliance). Klepin, Heidi D , Ritchie, Ellen , Major-Elechi, Brittny ... - - J Geriatr Oncol - 2020 Manuscript - Primary - Primary - Older Adult - CALGB-361006
Recombinant Interleukin-2 in Patients Aged Younger Than 60 Years With Acute Myeloid Leukemia in First Complete Remission Kolitz, Jonathan E. , George, Stephen L. , Benson, Don M. ... - - Cancer - 2014 Manuscript - Primary - Long-Term-Followup - Leukemia - CALGB-19808
P-glycoprotein inhibition using valspodar (PSC-833) does not improve outcomes for patients younger than age 60 years with newly diagnosed acute myeloid leukemia: Cancer and Leukemia Group B study 19808 Kolitz, Jonathan E. , George, Stephen L. , Marcucci, Guido ... - - Blood - 2010 Manuscript - Primary - Primary - Leukemia - CALGB-19808 , CALGB-8461
High expression of IGFBP2 is associated with chemoresistance in adult acute myeloid leukemia Kühnl, Andrea , Kaiser, Martin , Neumann, Martin , Fransecky, Lars ... - - Leuk. Res. - 2011 Manuscript - Secondary - Primary - Leuk Corr Sci - C9665 , C20202 , C9621 , C8461
Low Meningioma 1 (MN1) gene expression to predict outcome in cytogenetically normal acute myeloid leukemia (CN-AML): A Cancer and Leukemia Group B (CALGB) study Langer, C. , Maharry, K. S. , Mrozek, K. A. , Paschka, P. ... - - J. Clin. Oncol. - 2008 Abstract - Secondary - Primary - Leuk Corr Sci - CALGB-19808 , CALGB-20502 , CALGB-9621
High BAALC expression associates with other molecular prognostic markers, poor outcome and a distinct gene expression signature in cytogenetically normal acute myeloid leukemia (CN AML): A Cancer and Leukemia Group B (CALGB) study Langer, C. , Ruppert, A. S. , Radmacher, M. D. , Whitman, S. P. ... - - J. Clin. Oncol. - 2007 Abstract - Secondary - Primary - Leuk Corr Sci - CALGB-19808 , CALGB-20502 , CALGB-8461 , CALGB-9621 , CALGB-9665
Prognostic Importance of MN1 Transcript Levels, and Biologic Insights From MN1-Associated Gene and MicroRNA Expression Signatures in Cytogenetically Normal Acute Myeloid Leukemia: A Cancer and Leukemia Group B Study Langer, Christian , Marcucci, Guido , Holland, Kelsi B. ... - - J Clin Oncol - 2009 Manuscript - Secondary - Primary - Leuk Corr Sci - CALGB-19808 , CALGB-20502 , CALGB-8461 , CALGB-9621 , CALGB-9665
High BAALC expression associates with other molecular prognostic markers, poor outcome, and a distinct gene-expression signature in cytogenetically normal patients younger than 60 years with acute myeloid leukemia: a Cancer and Leukemia Group B (CALGB) study Langer, Christian , Radmacher, Michael D. , Ruppert, Amy S. ... - - Blood - 2008 Manuscript - Secondary - Primary - Leuk Corr Sci - CALGB-19808 , CALGB-20502 , CALGB-8461 , CALGB-9621 , CALGB-9665
An Analysis of Maintenance Therapy and Post-Midostaurin Outcomes in the International Prospective Randomized, Placebo-Controlled, Double-Blind Trial (CALGB 10603/RATIFY [Alliance]) for Newly Diagnosed Acute Myeloid Leukemia (AML) Patients with FLT3 Mutations Larson, Richard A. , Mandrekar, Sumithra , Sanford, Ben L ... - ASH - Blood - 2017 Abstract - Secondary - Primary - Leukemia - CALGB-10603
Up-regulation of a HOXA-PBX3 homeobox-gene signature following down-regulation of miR-181 is associated with adverse prognosis in patients with cytogenetically abnormal AML Li, Z. , Huang, H. , Li, Y. , Jiang, X. , Chen, P. , Arnovitz, S. ... - - Blood - 2012 Manuscript - Secondary-not-in-original - Primary - Leuk Corr Sci - C9665
Activation of a Mir-181-Targeting HOXA-PBX3 Homeobox Gene Signature Is Associated with Adverse Prognosis of Cytogenetically Abnormal Acute Myeloid Leukemia Li, Z. , Huang, H. , Li, Y. , Jiang, X. , Chen, P. , Arnovitz, S. ... - ASH - ASH Annual Meeting Abstracts - 2011 Abstract - Secondary-not-in-original - Primary - Leuk Corr Sci - C9665
Identification of a 24-Gene Prognostic Signature That Improves the European LeukemiaNet Risk Classification of Acute Myeloid Leukemia: An International Collaborative Study Li, Zejuan , Herold, Tobias , He, Chunjiang , Valk, Peter J.M. ... - - J. Clin. Oncol - 2013 Manuscript - Secondary-not-in-original - Meta-Analysis - Leukemia - CALGB-19808 , CALGB-9222 , CALGB-9621 , CALGB-9710 , CALGB-9720
Sp1/NFκB/HDAC/miR-29b Regulatory Network in KIT-driven Myeloid Leukemia Liu, Shujun , Wu, Lai-Chu , Pang, Jiuxia , Santhanam, Ramasamy ... - - Cancer Cell - 2010 Manuscript - Secondary - Primary - Leuk Corr Sci - C9665
Variations of the ataxia telangiectasia mutated gene in patients with chronic lymphocytic leukemia lack substantial impact on progression-free survival and overall survival: a Cancer and Leukemia Group B study Lozanski, Gerard , Ruppert, Amy S. , Heerema, Nyla A. ... - - Leuk. Lymphoma - 2012 Manuscript - Secondary - Primary - Leuk Corr Sci - CALGB-9712 , CALGB-9665
Comparison Of Deep Sequencing and Allele-Specific Oligonucleotide PCR Methods For MRD Quantitation In Acute Lymphoblastic Leukemia and Mantle Cell Lymphoma: CALGB 10403 and CALGB 59909 (Alliance) Malnassy, Greg , Geyer, Susan , Fulton, Noreen , Koval, Greg ... - - Blood - 2013 Abstract - Secondary-not-in-original - Meta-Analysis - Leuk Corr Sci - CALGB-10403 , CALGB-59909
Improving the molecular risk classification for younger (<60 years) de novo cytogenetically normal acute myeloid leukemia (CN AML) patients (pts) Marcucci, G. , Maharry, K. S. , Whitman, S. P. , Paschka, P. ... - ASCO - J. Clin. Oncol. - 2009 Abstract - Secondary - Primary - Leuk Corr Sci - CALGB-19808 , CALGB-20202 , CALGB-9621
High ERG expression levels predict adverse outcome and refine molecular risk-based classification of cytogenetically normal (CN) acute myeloid leukemia (AML): A Cancer and Leukemia Group B (CALGB) study Marcucci, G. , Maharry, K. S. , Whitman, S. P. , Vukosavljevic, T. ... - AACR - AACR Annual Meeting - 2007 Abstract - Secondary - Primary - Leuk Corr Sci - CALGB-19808 , CALGB-20502 , CALGB-8461 , CALGB-9621 , CALGB-9665
IDH1 and IDH2 gene mutations identify novel molecular subsets within de novo cytogenetically normal acute myeloid leukemia (CN-AML): A Cancer and Leukemia Group B (CALGB) Study Marcucci, G. , Maharry, K. S. , Wu, Y. , Radmacher, M. D. ... - - Haematologica - 2010 Abstract - Secondary - Primary - Leuk Corr Sci - C8525 , CALGB-10201 , CALGB-19808 , CALGB-20202 , CALGB-20502 , CALGB-8461 , CALGB-8923 , CALGB-9420 , CALGB-9621 , CALGB-9665 , CALGB-9720
Gene and microRNA (miRNA) Expression Signatures and Prognostic Significance of CEBPA Mutations in Cytogenetically Normal (CN) Acute Myeloid Leukemia (AML) with High-Risk Molecular Features: A Cancer and Leukemia Group B (CALGB) Study Marcucci, G. , Maharry, K. , Radmacher, M. D. , Mrozek, K. ... - - Blood - 2007 Abstract - Secondary - Primary - Leuk Corr Sci - CALGB-19808 , CALGB-20205 , CALGB-20502 , CALGB-8461 , CALGB-9621 , CALGB-9665
A phase III randomized trial of intensive induction and consolidation chemotherapy +/- oblimersen, a pro-apoptotic Bcl-2 antisense oligonucleotide in untreated acute myeloid leukemia patients >60 years old Marcucci, G. , Moser, B. K. , Blum, W. G. , Stock, W. , Wetzler, M. ... - ASCO - J. Clin. Oncol. - 2007 Abstract - Primary - Primary - Leukemia - CALGB-10201
Combination of dasatinib with chemotherapy in previously untreated core binding factor acute myeloid leukemia: CALGB 10801 Marcucci, Guido , Geyer, Susan , Laumann, Kristina , Zhao, Weiqiang ... - - Blood Adv - 2020 Manuscript - Primary - Primary - Leukemia - CALGB-10801 , CALGB-20202
Adding the KIT Inhibitor Dasatinib (DAS) to Chemotherapy Overcomes the Negative Impact of KIT Mutation/over-expression in Core Binding Factor (CBF) Acute Myeloid Leukemia (AML): Results from CALGB study 10801 (Alliance) Marcucci, Guido , Geyer, Susan , Zhao, John , Caroll, Andrew J ... - ASH - Blood - 2014 Abstract - Primary - Primary - Leukemia - CALGB-10801
Adding The KIT Inhibitor Dasatinib (DAS) To Standard Induction and Consolidation Therapy For Newly Diagnosed Patients (pts) With Core Binding Factor (CBF) Acute Myeloid Leukemia (AML): Initial Results Of The CALGB 10801 (Alliance) Study Marcucci, Guido , Geyer, Susan , Zhao, John , Caroll, Andrew J ... - ASH - Blood - 2013 Abstract - Secondary - Primary - Leuk Corr Sci - CALGB-10801
Clinical Role of microRNAs in Cytogenetically Normal Acute Myeloid Leukemia: miR-155 Upregulation Independently Identifies High-Risk Patients Marcucci, Guido , Maharry, Kati S. , Metzeler, Klaus H. ... - - J. Clin. Oncol. - 2013 Manuscript - Secondary - Primary - Leuk Corr Sci - CALGB-8461 , CALGB-9665 , CALGB-20202
Prognostic Significance of, and Gene and MicroRNA Expression Signatures Associated With, CEBPA Mutations in Cytogenetically Normal Acute Myeloid Leukemia With High-Risk Molecular Features: A Cancer and Leukemia Group B Study Marcucci, Guido , Maharry, Kati , Radmacher, Michael D. ... - - J Clin Oncol - 2008 Manuscript - Secondary - Primary - Leuk Corr Sci - CALGB-19808 , CALGB-20502 , CALGB-8461 , CALGB-9621 , CALGB-9665
High expression levels of the ETS-related gene, ERG, predict adverse outcome and improve molecular risk-based classification of cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B Study. Marcucci, Guido , Maharry, Kati , Whitman, Susan P ... - - J. Clin. Oncol. - 2007 Manuscript - Secondary - Primary - Leuk Corr Sci - CALGB-19808 , CALGB-20205 , CALGB-20502 , CALGB-8461 , CALGB-9621 , CALGB-9665
IDH1 and IDH2 Gene Mutations Identify Novel Molecular Subsets Within De Novo Cytogenetically Normal Acute Myeloid Leukemia: A Cancer and Leukemia Group B Study Marcucci, Guido , Maharry, Kati , Wu, Yue-Zhong ... - - J Clin Oncol - 2010 Manuscript - Secondary - Primary - Leuk Corr Sci - C8421 , C8525 , CALGB-10201 , CALGB-19808 , CALGB-20202 , CALGB-20502 , CALGB-8923 , CALGB-9420 , CALGB-9621 , CALGB-9665 , CALGB-9720
Age-Related Prognostic Impact of Different Types of DNMT3A Mutations in Adults With Primary Cytogenetically Normal Acute Myeloid Leukemia Marcucci, Guido , Metzeler, Klaus H. , Schwind, Sebastian ... - - J. Clin. Oncol. - 2012 Manuscript - Secondary - Primary - Leuk Corr Sci - CALGB-9621 , CALGB-19808
MicroRNA expression in cytogenetically normal acute myeloid leukemia. Marcucci, Guido , Radmacher, Michael D , Maharry, Kati ... - - N. Engl. J. Med. - 2008 Manuscript - Secondary - Primary - Leuk Corr Sci - CALGB-19808 , CALGB-20502 , CALGB-8461 , CALGB-9621 , CALGB-9665
Epigenetics Meets Genetics in Acute Myeloid Leukemia: Clinical Impact of a Novel Seven-Gene Score Marcucci, Guido , Yan, Pearlly , Maharry, Kati , Frankhouser, David ... - - J. Clin. Oncol - 2014 Manuscript - Secondary - Primary - Leuk Corr Sci - CALGB-10201 , CALGB-9420 , CALGB-9720 , CALGB-9621 , CALGB-19808
Poor Outcome of RUNX1-Mutated (RUNX1-mut) Patients (Pts) with Primary, Cytogenetically Normal Acute Myeloid Leukemia (CN-AML) and Associated Gene- and MicroRNA (miR) Expression Signatures Mendler, J. H. , Maharry, K. , Radmacher, M. D. , Mrozek, K. ... - - Blood - 2011 Abstract - Secondary - Primary - Leuk Corr Sci - C8525 , CALGB-10201 , CALGB-19808 , CALGB-8923 , CALGB-9420 , CALGB-9621 , CALGB-9720
RUNX1 Mutations Are Associated With Poor Outcome in Younger and Older Patients With Cytogenetically Normal Acute Myeloid Leukemia and With Distinct Gene and MicroRNA Expression Signatures Mendler, Jason H. , Maharry, Kati , Radmacher, Michael D. ... - - J. Clin. Oncol. - 2012 Manuscript - Secondary - Primary - Leuk Corr Sci - C8525 , CALGB-8461 , CALGB-8923 , CALGB-9420 , CALGB-9621 , CALGB-9665 , CALGB-9720 , CALGB-10201 , CALGB-19808 , CALGB-20202
ASXL1 Mutations Identify a High-Risk Subgroup of Older Patients with Primary Cytogenetically Normal Acute Myeloid Leukemia within the European LeukemiaNet 'Favorable' Genetic Category Metzeler, K. H. , Becker, H. , Maharry, K. , Radmacher, M. D. ... - - Blood - 2011 Abstract - Secondary - Primary - Leuk Corr Sci - CALGB-20202 , CALGB-8461 , CALGB-9665
An 86-Probe Gene Expression Signature Can Predict Survival in AML with Normal Karyotype Independently of FLT3 ITD and NPM1 Mutation Status - A Collaborative Study from the AMLCG and CALGB Study Groups Metzeler, K. H. , Hummel, M. , Bloomfield, C. D. , Spiekermann, K. ... - - Blood - 2007 Abstract - Secondary - Primary - Leuk Corr Sci - CALGB-8461 , CALGB-9621 , CALGB-9665
TET2 mutations occur in over 20% of adults with de novo cytogenetically normal AML, and their prevalence increases with age: A Cancer and Leukemia Goup B study. Metzeler, K. H. , Maharry, K. , Margeson, D. , Curfman, J. ... - - Haematologica - 2010 Abstract - Secondary - Primary - Leuk Corr Sci - C8525 , CALGB-10201 , CALGB-19808 , CALGB-20202 , CALGB-20502 , CALGB-8461 , CALGB-8923 , CALGB-9420 , CALGB-9621 , CALGB-9665 , CALGB-9720
Mutations In the Tet Oncogene Family Member 2 (TET2) Gene Refine the New European LeukemiaNet Risk Classification of Primary, Cytogenetically Normal Acute Myeloid Leukemia (CN-AML) In Adults: A Cancer and Leukemia Group B (CALGB) Study Metzeler, K. H. , Maharry, K. , Radmacher, M. D. , Mrozek, K. ... - - Blood - 2010 Abstract - Secondary - Primary - Leuk Corr Sci - C8525 , C8641 , CALGB-10201 , CALGB-19808 , CALGB-20202 , CALGB-20502 , CALGB-8923 , CALGB-9420 , CALGB-9621 , CALGB-9665 , CALGB-9720
A stem cell-like gene expression signature associates with inferior outcomes and a distinct microRNA expression profile in adults with primary cytogenetically normal acute myeloid leukemia Metzeler, KH , Maharry, K , Kohlschmidt, J , Volinia, S , Mrózek, K ... - - Leukemia - 2013 Manuscript - Secondary - Primary - Leuk Corr Sci - CALGB-8461 , CALGB-9665 , CALGB-20202
ASXL1 mutations identify a high-risk subgroup of older patients with primary cytogenetically normal AML within the ELN Favorable genetic category Metzeler, Klaus H. , Becker, Heiko , Maharry, Kati ... - - Blood - 2011 Manuscript - Secondary - Primary - Leuk Corr Sci - CALGB-20202 , CALGB-8461 , CALGB-9665
An 86-probe-set gene-expression signature predicts survival in cytogenetically normal acute myeloid leukemia Metzeler, Klaus H. , Hummel, Manuela , Bloomfield, Clara D. ... - - Blood - 2008 Manuscript - Secondary-not-in-original - Meta-Analysis - Leuk Corr Sci - CALGB-8461 , CALGB-9621 , CALGB-9665
TET2 Mutations Improve the New European LeukemiaNet Risk Classification of Acute Myeloid Leukemia: A Cancer and Leukemia Group B Study Metzeler, Klaus H. , Maharry, Kati , Radmacher, Michael D. ... - - J Clin Oncol - 2011 Manuscript - Secondary - Primary - Leuk Corr Sci - C8525 , CALGB-10201 , CALGB-19808 , CALGB-20202 , CALGB-20502 , CALGB-8461 , CALGB-8923 , CALGB-9420 , CALGB-9621 , CALGB-9665 , CALGB-9720
Prognostic Significance of Unbalanced Chromosome Abnormalities Used by 2008 World Health Organization (WHO) Classification to Define Acute Myeloid Leukemia (AML) with Myelodysplasia-Related Changes in Adults: a Cancer and Leukemia Group B (CALGB) Study Mrozek, K. , Holland, K. B. , Pettenati, M. J. , Maharry, K. ... - ASH - Blood - 2009 Abstract - Secondary-not-in-original - Primary - Leuk Corr Sci - Comprehensive
Prognostic Utility of the European LeukemiaNet (ELN) Genetic-Risk Classification in Adults with De Novo Acute Myeloid Leukemia (AML): A Study of 1,550 Patients (Pts) Mrozek, K. , Marcucci, G. , Maharry, K. , Nicolet, D. , Becker, H. ... - - Blood - 2011 Abstract - Secondary - Primary - Leuk Corr Sci - C8525 , CALGB-10201 , CALGB-19808 , CALGB-20202 , CALGB-8461 , CALGB-8923 , CALGB-9420 , CALGB-9621 , CALGB-9665 , CALGB-9720
Prognostic Significance of the European LeukemiaNet Standardized System for Reporting Cytogenetic and Molecular Alterations in Adults With Acute Myeloid Leukemia Mrózek, Krzysztof , Marcucci, Guido , Nicolet, Deedra ... - - J. Clin. Oncol. - 2012 Manuscript - Secondary - Primary - Leuk Corr Sci - CALGB-10201 , CALGB-19808 , CALGB-8461 , CALGB-8525 , CALGB-8923 , CALGB-9420 , CALGB-9621 , CALGB-9720
Clinical relevance of mutations and gene-expression changes in adult acute myeloid leukemia with normal cytogenetics: are we ready for a prognostically prioritized molecular classification? Mrózek, Krzysztof , Marcucci, Guido , Paschka, Peter ... - - Blood - 2007 Manuscript - No-Endpoint - Other - Leuk Corr Sci - No Study Assigned
Patients With Acute Myeloid Leukemia and RAS Mutations Benefit Most From Postremission High-Dose Cytarabine: A Cancer and Leukemia Group B Study Neubauer, Andreas , Maharry, Kati , Mrózek, Krzysztof ... - - J Clin Oncol - 2008 Manuscript - Secondary - Primary - Leuk Corr Sci - C8525 , C8765 , CALGB-8461 , CALGB-9665
FTY720, a new and alternative strategy for treating blast crisis CML and Ph1 ALL patients Neviani, P. , Santhanam, R. , Oaks, J. , Eiring, A. , Notari, M. ... - AACR - AACR Annual Meeting - 2007 Abstract - Secondary-not-in-original - Primary - Leuk Corr Sci - CALGB-8461 , CALGB-9665
FTY720, a new alternative for treating blast crisis chronic myelogenous leukemia and Philadelphia chromosome–positive acute lymphocytic leukemia Neviani, Paolo , Santhanam, Ramasamy , Oaks, Joshua J. ... - - J Clin Invest - 2007 Manuscript - Secondary-not-in-original - Primary - Leuk Corr Sci - CALGB-8461 , CALGB-9665
High expression of DNMT3B negatively impacts on clinical outcome of older patients (pts) with primary cytogenetically normal (CN) acute myeloid leukemia (AML) [CALGB 20202 (Alliance)]. Niederwieser, C. , Kohlschmidt, J. , Maharry, K. , Mrózek, K. ... - EHA - European Hematology Association Congress - 2013 Abstract - Secondary - Primary - Leuk Corr Sci - CALGB-20202
Prognostic and biologic significance of DNMT3B expression in older patients with cytogenetically normal primary acute myeloid leukemia Niederwieser, Christian , Kohlschmidt, Jessica , Volinia, Stefano ... - - Leukemia - 2015 Manuscript - Secondary - Primary - Leuk Corr Sci - C8461 , C9665 , CALGB-10201 , CALGB-20202 , CALGB-8525 , CALGB-8923 , CALGB-9420 , CALGB-9720
Differential Clinical Impact Of Gene Mutations and Their Combinations In Primary Cytogenetically Normal Acute Myeloid Leukemia (CN-AML) Papaioannou, Dimitrios , Maharry, Kati , Mrózek, Krzysztof ... - ASH - Blood - 2013 Abstract - Secondary - Primary - Leuk Corr Sci - CALGB-20202 , CALGB-9665 , CALGB-8461
Prognostic and biological significance of the proangiogenic factor EGFL7 in acute myeloid leukemia Papaioannou, Dimitrios , Shen, Changxian , Nicolet, Deedra ... - - Proc. Natl. Acad. Sci. U.S.A - 2017 Manuscript - Secondary - Primary - Leuk Corr Sci - CALGB-10201 , CALGB-10503 , CALGB-10603 , CALGB-19808 , CALGB-20202 , CALGB-8461 , CALGB-8525 , CALGB-8923 , CALGB-9022 , CALGB-9120 , CALGB-9222 , CALGB-9420 , CALGB-9665 , CALGB-9720
Prognostic impact of NPM1 mutations in cytogenetically normal (CN) acute myeloid leukemia (AML) is adversely affected by high expression of the ERG gene: A Cancer and Leukemia Group B (CALGB) study Paschka, P. , Marcucci, G. , Maharry, K. S. , Whitman, S. P. ... - EHA - Haematol-Hematol J - 2007 Abstract - Secondary - Primary - Leuk Corr Sci - CALGB-19808 , CALGB-20502 , CALGB-8461 , CALGB-9621 , CALGB-9665
Wilms Tumor 1 (WT1) Gene Mutations Predict Poor Outcome in Adults with Cytogenetically Normal (CN) Acute Myeloid Leukemia (AML): A Cancer and Leukemia Group B (CALGB) Study Paschka, P. , Marcucci, G. , Ruppert, A. S. , Mrozek, K. ... - - Blood - 2007 Abstract - Secondary - Primary - Leuk Corr Sci - CALGB-19808 , CALGB-20502 , CALGB-8461 , CALGB-9621 , CALGB-9665
Outcome prediction in adult core binding factor (CBF) acute myeloid leukemia (AML) with gene expression profiling: A Cancer and Leukemia Group B (CALGB) study Paschka, P. , Radmacher, M. D. , Marcucci, G. , Ruppert, A. S. ... - ASCO - J. Clin. Oncol. - 2007 Abstract - Secondary - Primary - Leuk Corr Sci - C8525 , C9022 , CALGB-19808 , CALGB-8461 , CALGB-9222 , CALGB-9621 , CALGB-9665
Wilms’ Tumor 1 Gene Mutations Independently Predict Poor Outcome in Adults With Cytogenetically Normal Acute Myeloid Leukemia: A Cancer and Leukemia Group B Study Paschka, Peter , Marcucci, Guido , Ruppert, Amy S. ... - - J Clin Oncol - 2008 Manuscript - Secondary - Primary - Leuk Corr Sci - CALGB-19808 , CALGB-20502 , CALGB-8461 , CALGB-9621 , CALGB-9665
Multiplexed Digital Quantification of mRNA Abundance: a Highly Reproducible, PCR-independent Assessment of BAALC, ERG, and MN1 mRNA Levels in Acute Myeloid Leukemia (AML) Bone Marrow (BM) and Peripheral Blood (PB) Samples Payton, J. E. , Marcucci, G. , Radmacher, M. D. , Maharry, K. ... - ASH - ASH Annual Meeting Abstracts - 2009 Abstract - Secondary - Primary - Leuk Corr Sci - C9665 , C8461
MicroRNA (miR) expression signatures in molecular subsets of cytogenetically normal (CN) acute myeloid leukemia (AML): A Cancer and Leukemia Group B (CALGB) study Radmacher, M. D. , Marcucci, G. , Paschka, P. , Vukosavljevic, T. ... - - J. Clin. Oncol. - 2007 Abstract - Secondary - Primary - Leuk Corr Sci - CALGB-19808 , CALGB-20502 , CALGB-8461 , CALGB-9621 , CALGB-9665
Randomized trial of 10 days of decitabine ± bortezomib in untreated older patients with AML: CALGB 11002 (Alliance) Roboz, Gail J. , Mandrekar, Sumithra J. , Desai, Pinkal ... - - Blood Adv - 2018 Manuscript - Primary - Primary - Leukemia - CALGB-11002
Higher MN1 expression is an unfavorable prognosticator in older patients (Pts) with cytogenetically normal acute myeloid leukemia (CN-AML): A CALGB study Schwind, S. , Marcucci, G. , Holland, K. B. , Mrózek, K. ... - AACR - AACR Annual Meeting - 2010 Abstract - Secondary - Primary - Leuk Corr Sci - C20502 , C9665 , C8461 , C9621 , C19808
MicroRNA 181a (miR-181a) expression as a prognosticator in cytogenetically normal acute myeloid leukemia (CN AML) Schwind, S. , Marcucci, G. , Maharry, K. S. , Radmacher, M. D. ... - - J. Clin. Oncol. - 2009 Abstract - Secondary - Primary - Leuk Corr Sci - C9621 , CALGB-19808
Aberrant Gene Expression of BAALC and ERG in Older >= 60 Years (y) De Novo Cytogenetically Normal Acute Myeloid Leukemia (CN-AML): A Cancer and Leukemia Group B (CALGB) Study Schwind, S. , Marcucci, G. , Maharry, K. , Mrozek, K. ... - - Blood - 2009 Abstract - Secondary - Primary - Leuk Corr Sci - CALGB-10201 , CALGB-20202 , CALGB-8461 , CALGB-9720
inv(16)/t(16;16) acute myeloid leukemia with non–type A CBFB-MYH11 fusions associate with distinct clinical and genetic features and lack KIT mutations Schwind, Sebastian , Edwards, Colin G. , Nicolet, Deedra ... - - Blood - 2013 Manuscript - Secondary - Primary - Leuk Corr Sci - CALGB-8461 , CALGB-8525 , CALGB-8821 , CALGB-8923 , CALGB-9022 , CALGB-9120 , CALGB-9222 , CALGB-9621 , CALGB-9720 , CALGB-19808 , CALGB-10201 , CALGB-10502 , CALGB-10503 , CALGB-10603
Prognostic Significance of Expression of a Single MicroRNA, miR-181a, in Cytogenetically Normal Acute Myeloid Leukemia: A Cancer and Leukemia Group B Study Schwind, Sebastian , Maharry, Kati , Radmacher, Michael D. ... - - J Clin Oncol - 2010 Manuscript - Secondary - Primary - Leuk Corr Sci - CALGB-19808 , CALGB-20202 , CALGB-20502 , CALGB-8461 , CALGB-9621 , CALGB-9665
Low expression of MN1 associates with better treatment response in older patients with de novo cytogenetically normal acute myeloid leukemia Schwind, Sebastian , Marcucci, Guido , Kohlschmidt, Jessica ... - - Blood - 2011 Manuscript - Secondary - Primary - Leuk Corr Sci - C8525 , CALGB-10201 , CALGB-20202 , CALGB-8461 , CALGB-8923 , CALGB-9420 , CALGB-9665 , CALGB-9720
BAALC and ERG expression levels are associated with outcome and distinct gene and microRNA expression profiles in older patients with de novo cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study Schwind, Sebastian , Marcucci, Guido , Maharry, Kati ... - - Blood - 2010 Manuscript - Secondary - Primary - Leuk Corr Sci - C8525 , CALGB-10201 , CALGB-20202 , CALGB-8923 , CALGB-9420 , CALGB-9720
Dose Intensification of Daunorubicin and Cytarabine during Treatment of Adult Acute Lymphoblastic Leukemia: Results of Cancer and Leukemia Group B Study 19802 Stock, Wendy , Johnson, Jeffrey L. , Stone, Richard M. ... - - Cancer - 2013 Manuscript - Primary - Primary - Leukemia - CALGB-19802
A pediatric regimen for older adolescents and young adults with acute lymphoblastic leukemia: results of CALGB 10403 Stock, Wendy , Luger, Selina M. , Advani, Anjali S. , Yin, Jun ... - - Blood - 2019 Manuscript - Primary - Primary - Leukemia - CALGB-10403
Favorable outcomes for adolescents and young adults (AYA) with Acute Lymphoblastic Leukemia (ALL): Early results of US Intergroup trial CALGB 10403 (Alliance) Stock, Wendy , Luger, Selina , Advani, Anjali , Geyer, Susan ... - ASH - Blood - 2014 Abstract - Primary - Preliminary - Leukemia - CALGB-10403
CALGB 10603 (RATIFY): A randomized phase III study of induction (daunorubicin/cytarabine) and consolidation (high-dose cytarabine) chemotherapy combined with midostaurin or placebo in treatment-naive patients with FLT3 mutated AML Stone, R. M. , Dohner, H. , Ehninger, G. , Villeneuve, M. ... - - J. Clin. Oncol. - 2011 Abstract - Secondary - Preliminary - Leukemia - CALGB-10603
Midostaurin plus Chemotherapy for Acute Myeloid Leukemia with a FLT3 Mutation Stone, Richard M. , Mandrekar, Sumithra J. , Sanford, Ben L. ... - - N. Engl. J. Med. - 2017 Manuscript - Primary - Primary - Leukemia - CALGB-10603
The Addition of Midostaurin to Standard Chemotherapy Decreases Cumulative Incidence of Relapse (CIR) in the International Prospective Randomized, Placebo-Controlled, Double-Blind Trial (CALGB 10603 / RATIFY [Alliance]) for Newly Diagnosed Acute Myeloid Leukemia (AML) Patients with FLT3 Mutations Stone, Richard M. , Mandrekar, Sumithra , Sanford, Ben L ... - ASH - Blood - 2017 Abstract - Secondary-not-in-original - Primary - Leukemia - CALGB-10603
Midostaurin v Placebo plus Daunorubicin/Cytarabine Induction, High-dose Cytarabine Consolidation and Maintenance Therapy in Newly Diagnosed Acute Myeloid Leukemia ( AML) Patients ( pts) age 18-60 with FLT3 mutations: An International Prospective Randomized Placebo-Controlled Double-Blind Trial (CALGB 10603 [Alliance]) Stone, Richard M. , Mandrekar, Sumithra , Sanford, Ben L ... - ASH - Blood - 2015 Abstract - Secondary - Primary - Leukemia - CALGB-10603
High Dose Cytarabine plus Gemtuzumab Ozogamicin for Patients with Relapsed or Refractory Acute Myeloid Leukemia: Cancer and Leukemia Group B Study 19902 Stone, Richard M. , Moser, Barry , Sanford, Ben , Schulman, Philip ... - - Leuk Res - 2011 Manuscript - Primary - Primary - Leukemia - CALGB-19902
A phase II study of continuous infusion homoharringtonine and cytarabine in newly diagnosed patients with chronic myeloid leukemia: CALGB study 19804. Stone, Richard M , Donohue, Kathleen A , Stock, Wendy , Hars, Vera ... - - Cancer Chemother. Pharmacol. - 2009 Manuscript - Primary - Primary - Leukemia - CALGB-19804
Allogeneic Hematopoietic Cell Transplantation (HCT) vs. Non-HCT Consolidation Therapies in Acute Myeloid Leukemia (AML) Patients 60-75 Years of Age in First Complete Remission (CR1): An Alliance (A151509), SWOG, ECOG and CIBMTR Study Ustun, Celalettin , Le-Rademacher, Jennifer G , Wang, Hailin ... - ASH - Blood - 2018 Abstract - Primary - Primary - Leukemia - A151509 , CALGB-100103
Allogeneic Hematopoietic Cell Transplantation Compared to Chemotherapy Consolidation in older Acute Myeloid Leukemia (AML) Patients 60–75 Years in First Complete Remission (CR1): An Alliance (A151509), SWOG, ECOG-ACRIN and CIBMTR Study Ustun, Celalettin , Le-Rademacher, Jennifer , Wang, Hai-Lin ... - - Leukemia - 2019 Manuscript - Primary - Primary - Older Adult - A151509 , CALGB-10502 , CALGB-10801 , CALGB-11001 , CALGB-11002 , E3999 , S0432 , S0703
A phase 2 study incorporating sorafenib into the chemotherapy for older adults with FLT3-mutated acute myeloid leukemia: CALGB 11001 Uy, Geoffrey L. , Mandrekar, Sumithra J. , Laumann, Kristina ... - - Blood Adv - 2017 Manuscript - Primary - Primary - Leukemia - CALGB-11001
Addition of Sorafenib to Chemotherapy Improves the Overall Survival of Older Adults With FLT3-ITD Mutated AML (Alliance C11001). Uy, Geoffrey L. , Mandrekar, Sumithra , Laumann, Kristina ... - ASH - Blood - 2015 Abstract - Primary - Primary - Leukemia - CALGB-11001
Initial Results Of a Phase II Trial Of Sorafenib Plus Standard Induction In Older Adults With Mutant FLT3 Acute Myeloid Leukemia (AML) (Alliance trial C11001) Uy, Geoffrey L. , Sanford, Ben , Marcucci, Guido , Zhao, Weiqiang ... - ASH - Blood - 2013 Abstract - Primary - Preliminary - Leukemia - CALGB-11001
Midostaurin in patients with acute myeloid leukemia and FLT3-TKD mutations: a subanalysis from the RATIFY trial Voso, Maria Teresa , Larson, Richard A. , Jones, Dan ... - - Blood Adv - 2020 Manuscript - Secondary-not-in-original - Primary - Leukemia - CALGB-10603
RATIFY: Prognostic impact of FLT3 tyrosine kinase domain (TKD) and NPM1 mutation status in patients with newly diagnosed acute myeloid leukemia (AML) treated with midostaurin or placebo plus standard chemotherapy (Alliance) Voso, Maria Teresa , Larson, Richard A. , Prior, Thomas W ... - ASH - Blood - 2018 Abstract - Secondary-not-in-original - Primary - Leukemia - CALGB-10603
Ratify (Alliance 10603): Prognostic Impact of FLT3 Tyrosine Kinase Domain (TKD) and NPM1 Mutation Status in Patients with Newly Diagnosed Acute Myeloid Leukemia (AML) Treated with Midostaurin Plus Standard Chemotherapy Voso, Maria Teresa , Larson, Richard A. , Prior, Thomas W ... - EHA - HemaSphere - 2019 Abstract - Secondary-not-in-original - Primary - Leukemia - CALGB-10603
New Recurrent Balanced Translocations in Acute Myeloid Leukemia and Myelodysplastic Syndromes: Cancer and Leukemia Group B (CALGB) 8461 Walker, A. , Mrózek, K. , Kohlschmidt, J. , Rao, K. W. ... - - Genes Chromosomes Cancer - 2013 Manuscript - Secondary - Primary - Leuk Corr Sci - CALGB-8461
Autologous Transplantation for Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia Achieves Outcomes Similar to Allogeneic Transplantation - Results of CALGB 10001 (Alliance) Wetzler, M. , Watson, D. , Stock, W. , Owzar, K. , Koval, G. , Hoke, E. ... - - Blood - 2012 Abstract - Primary - Primary - Leukemia - CALGB-10001
Intensive induction is effective in selected octogenarian acute myeloid leukemia patients: prognostic significance of karyotype and selected molecular markers used in the European LeukemiaNet classification Wetzler, Meir , Mrózek, Krzysztof , Kohlschmidt, Jessica ... - - Haematologica - 2014 Manuscript - Secondary-not-in-original - Primary - Leuk Corr Sci - C8221 , C8525 , C9720 , CALGB-10201 , CALGB-8923
Autologous transplantation for Philadelphia chromosome-positive acute lymphoblastic leukemia achieves outcomes similar to allogeneic transplantation: results of CALGB Study 10001 (Alliance) Wetzler, Meir , Watson, Dorothy , Stock, Wendy , Koval, Gregory ... - - Haematologica - 2014 Manuscript - Primary - Primary - Leukemia - CALGB-10001
Adverse Prognostic Impact of FLT3 Internal Tandem Duplication (ITD) Is Age-Associated in Older >= 60 Years (Y) De Novo cytogenetically Normal Acute Myeloid Leukemia (CN-AML) Patients (Pts): a Cancer and Leukemia Group B (CALGB) Study Whitman, S. P. , Maharry, K. , Radmacher, M. D. , Mrozek, K. ... - - Blood - 2009 Abstract - Secondary - Primary - Leuk Corr Sci - CALGB-10201 , CALGB-20202 , CALGB-8461 , CALGB-9720
Improved clinical outcome of cytogenetically normal acute myeloid leukemia patients with the MLL partial tandem duplication: A Cancer and Leukemia Group B (CALGB) study Whitman, S. P. , Ruppert, A. S. , Marcucci, G. , Mrozek, K. A. ... - - Cancer Res. - 2007 Abstract - Secondary-not-in-original - Primary - Leuk Corr Sci - CALGB-19808 , CALGB-20502 , CALGB-8461 , CALGB-9621 , CALGB-9665 , CALGB-9769
FLT3 D835/I836 mutations predict worse disease-free survival (DFS) in younger adults with cytogenetically normal acute myeloid leukemia (CN AML) without FLT3 internal tandem duplications (ITD): A Cancer and Leukemia Group B (CALGB) study Whitman, S. P. , Ruppert, A. S. , Radmacher, M. D. , Mrozek, K. A. ... - - J. Clin. Oncol. - 2007 Abstract - Secondary - Primary - Leuk Corr Sci - CALGB-19808 , CALGB-20502 , CALGB-8461 , CALGB-9621 , CALGB-9665
Adverse Prognostic Impact of GAS6 Expression in De Novo Cytogenetically Normal Acute Myeloid Leukemia (CN-AML) (CALGB 8461, 9665, 20202; Alliance) Whitman, S. , Kohlschmidt, J. , Maharry, K. , Nicolet, D. ... - - Blood - 2012 Abstract - Secondary - Primary - Leuk Corr Sci - CALGB-8461 , CALGB-9665 , CALGB-20202
The MLL partial tandem duplication in adults aged 60 years and older with de novo cytogenetically normal acute myeloid leukemia Whitman, SP , Caligiuri, MA , Maharry, K , Radmacher, MD ... - - Leukemia - 2012 Manuscript - Secondary - Primary - Leuk Corr Sci - CALGB-10201 , CALGB-8525 , CALGB-8923 , CALGB-9420 , CALGB-9720
DNA hypermethylation and epigenetic silencing of the tumor suppressor gene, SLC5A8, in acute myeloid leukemia with the MLL partial tandem duplication Whitman, Susan P. , Hackanson, Björn , Liyanarachchi, Sandya ... - - Blood - 2008 Manuscript - Secondary - Primary - Leuk Corr Sci - CALGB-20502 , CALGB-9665 , CALGB-9769
GAS6 expression identifies high-risk adult AML patients: potential implications for therapy Whitman, Susan P. , Kohlschmidt, Jessica , Maharry, Kati ... - - Leukemia - 2014 Manuscript - Secondary - Primary - Leuk Corr Sci - CALGB-8525 , CALGB-8923 , CALGB-9420 , CALGB-9621 , CALGB-9720 , CALGB-10201 , CALGB-19808
FLT3 internal tandem duplication associates with adverse outcome and gene- and microRNA-expression signatures in patients 60 years of age or older with primary cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study Whitman, Susan P. , Maharry, Kati , Radmacher, Michael D. ... - - Blood - 2010 Manuscript - Secondary - Primary - Leuk Corr Sci - C8461 , C8525 , CALGB-10201 , CALGB-8923 , CALGB-9420 , CALGB-9720
Long-term disease-free survivors with cytogenetically normal acute myeloid leukemia and MLL partial tandem duplication: a Cancer and Leukemia Group B study Whitman, Susan P. , Ruppert, Amy S. , Marcucci, Guido ... - - Blood - 2007 Manuscript - Secondary - Primary - Leuk Corr Sci - CALGB-19808 , CALGB-20502 , CALGB-8461 , CALGB-9621 , CALGB-9665 , CALGB-9769
FLT3 D835/I836 mutations are associated with poor disease-free survival and a distinct gene-expression signature among younger adults with de novo cytogenetically normal acute myeloid leukemia lacking FLT3 internal tandem duplications Whitman, Susan P. , Ruppert, Amy S. , Radmacher, Michael D. ... - - Blood - 2008 Manuscript - Secondary - Primary - Leuk Corr Sci - CALGB-19808 , CALGB-20502 , CALGB-8461 , CALGB-9621 , CALGB-9665
Event-free survival as a surrogate endpoint for overall survival in previously untreated acute myeloid leukemia: An individual patient-level analysis of multiple randomized trials (Alliance A151614) Yin, Jun , LaPlant, Betsy , Storrick, Elizabeth , Uy, Geoffrey L. ... - ASH - Blood - 2018 Abstract - Primary - Comprehensive - Leukemia - A151614 , CALGB-10201 , E1900 , CALGB-10603 , S0106
Evaluation of event-free survival as a robust end point in untreated acute myeloid leukemia (Alliance A151614) Yin, Jun , LaPlant, Betsy , Uy, Geoffrey L. , Marcucci, Guido ... - - Blood Adv - 2019 Manuscript - Primary - Primary - Leukemia - A151614 , CALGB-10201 , CALGB-10503 , CALGB-10603 , CALGB-10801 , CALGB-11001
Impact of the Timing of Complete Remission and Transplantation on Estimates of Event-Free Survival in Acute Myeloid Leukemia Yin, Jun , Laplant, Betsy R. , Uy, Geoffrey L. , Marcucci, Guido ... - ASH - JAMA Oncol - 2016 Abstract - Primary - Primary - Leukemia - A151614 , CALGB-10201 , CALGB-10503 , CALGB-10603 , CALGB-10801 , CALGB-11001