Alliance A071401: Phase II Trial of Focal Adhesion Kinase Inhibition in Meningiomas With Somatic NF2 Mutations.
- Citation:
- J Clin Oncol vol 41 (3) 618-628
- Year:
- 2023
- Type:
- Manuscript
- Funding:
- NCTN
- Endpoint:
- Primary
- Analysis:
- Preliminary
- Data Sharing:
- No-Data-Sharing
- Status:
- Presented/Published
- Citation Status:
- pmc-release
- Note:
- Methodological:
- No
- Biospecimen:
- No
- SDC:
- No
- Book Volume:
- 12
- Parents:
- 3250
- Children:
- None
- Pharmas:
- AstraZeneca, Eli Lilly, and GSK (Novartis)
- Grants:
- U10CA180821, U10CA180882, UG1CA233180, UG1CA233184, UG1CA233193, UG1CA233196, UG1CA233320, UG1CA233324, UG1CA233331, UG1CA233339, UG1CA232760, UG1CA233290, and U10CA180888 (SWOG).
- Corr. Author:
- Authors:
- Priscilla K Brastianos Erin L Twohy Elizabeth R Gerstner Timothy J Kaufmann A John Iafrate Jochen Lennerz Suriya Jeyapalan David E Piccioni Varun Monga Camilo E Fadul David Schiff Jennie W Taylor Sajeel A Chowdhary Chetan Bettegowda George Ansstas Macarena De La Fuente Mark D Anderson Nicole Shonka Denise Damek Jose Carrillo Lara J Kunschner-Ronan Rekha Chaudhary Kurt A Jaeckle Francis M Senecal Thomas Kaley Tara Morrison Alissa A Thomas Mary R Welch Fabio Iwamoto David Cachia Adam L Cohen Shivangi Vora Michael Knopp Ian F Dunn Priya Kumthekar Jann Sarkaria Susan Geyer Xiomara W Carrero Maria Martinez-Lage Daniel P Cahill Paul D Brown Caterina Giannini Sandro Santagata Frederick G Barker Evanthia Galanis
- Networks:
- CA088, CA249, CA824, COLUMBIA, CORA, FL028, FL086, LAPS-CO070, LAPS-IL036, LAPS-MA036, LAPS-MD017, LAPS-MN026, LAPS-MO011, LAPS-NH012, LAPS-NY016, LAPS-OH007, LAPS-OK003, MA011, MCRC, NE003, OH070, RI005, VA002, VA009, VT004
- Study
- Alliance-A071401
- Multiple Studies, or Legacy Studies in Alliance Study:
- Phases:
- 2
- Keywords:
- Humans, Focal Adhesion Protein-Tyrosine Kinases, Meningeal Neoplasms, Meningioma, Mutation, Neoplasm Recurrence, Local