Genome-Wide Meta-Analysis Validates a Role for S1PR1 in Microtubule Targeting Agent-Induced Sensory Peripheral Neuropathy
- Citation:
- Clin Pharmacol Ther vol 108 (3) 625-634
- Year:
- 2020
- Type:
- Manuscript
- Funding:
- NCTN
- Endpoint:
- Secondary-not-in-original
- Analysis:
- Meta-Analysis
- Data Sharing:
- No-Data-Sharing
- Status:
- Presented/Published
- Citation Status:
- pmc-release
- Note:
- Methodological:
- No
- Biospecimen:
- Yes
- SDC:
- No
- Book Volume:
- 10
- Parents:
- 2799
- Children:
- None
- Pharmas:
- Abraxis, Bristol-Myers, and Celgene
- Grants:
- U10CA180821, U10CA180882, U24CA196171, UG1CA233320, UG1CA233327, R01 CA192156, T32 GM007175, P01CA142538
- Corr. Author:
- Authors:
- Katherina C. Chua Chenling Xiong Carol Ho Taisei Mushiroda Chen Jiang Flora Mulkey Dongbing Lai Bryan P. Schneider Sara R. Rashkin John S. Witte Paula N. Friedman Mark J. Ratain Howard L. McLeod Hope S. Rugo Lawrence N. Shulman Michiaki Kubo Kouros Owzar Deanna L. Kroetz
- Networks:
- CA136, DE012, LAPS-IL036, LAPS-IL057, LAPS-MA036, NY018
- Study
- Multiple Studies, or Legacy Studies in Alliance Study:
- CALGB-40101, CALGB-40502
- Phases:
- 3
- Keywords:
- chemotherapy, sensory peripheral neuropathy, chemotherapy-induced peripheral neuropathy, genome-wide association, pharmacogenetics, S1PR1