The impact of cytochrome P450 2D6 metabolism in women receiving adjuvant tamoxifen.
- Citation:
- Breast Cancer Res Treat vol 101 (1) 113-21
- Year:
- 2007
- Type:
- Manuscript
- Funding:
- NCTN
- Endpoint:
- Secondary
- Analysis:
- Primary
- Data Sharing:
- No-Data-Sharing
- Status:
- Presented/Published
- Citation Status:
- pub
- Note:
- Methodological:
- No
- Biospecimen:
- Yes
- SDC:
- No
- Book Volume:
- Parents:
- None
- Children:
- None
- Pharmas:
- Grants:
- CA116201, U-01 GM61373, CA-25224, CA 90628-03, CA87898
- Corr. Author:
- Authors:
- Matthew P Goetz Stacey K Knox Vera J Suman James M Rae Stephanie L Safgren Matthew M Ames Daniel W Visscher Carol Reynolds Fergus J Couch Wilma L Lingle Richard M Weinshilboum Emily G Barr Fritcher Andrea M Nibbe Zeruesenay Desta Anne Nguyen David A Flockhart Edith A Perez James N Ingle
- Networks:
- Study
- NCCTG-89-30-52
- Multiple Studies, or Legacy Studies in Alliance Study:
- Phases:
- 3
- Keywords:
- Adult, Aged, Aged, 80 and over, Antineoplastic Agents, Hormonal, Breast Neoplasms, Chemotherapy, Adjuvant, Cytochrome P-450 CYP2D6, Cytochrome P-450 CYP2D6 Inhibitors, Female, Genotype, Humans, Kaplan-Meier Estimate, Middle Aged, Neoplasm Recurrence, Local, Proportional Hazards Models, Tamoxifen, Treatment Outcome