High expression levels of the ETS-related gene, ERG, predict adverse outcome and improve molecular risk-based classification of cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B Study.
- Citation:
- J Clin Oncol vol 25 (22) 3337-43
- Year:
- 2007
- Type:
- Manuscript
- Funding:
- NCTN
- Endpoint:
- Secondary
- Analysis:
- Primary
- Data Sharing:
- No-Data-Sharing
- Status:
- Presented/Published
- Citation Status:
- pub
- Note:
- Program:
- TRP
- Primary Committee:
- Leuk Corr Sci
- Sec. Committees:
- Pharmas:
- Grants:
- CA089341, CA09512, CA101140, CA102031, CA16058, CA31946, CA77658, CA90469, CA96887, CA98933
- Corr. Author:
- Authors:
- Guido Marcucci Kati Maharry Susan P Whitman Tamara Vukosavljevic Peter Paschka Christian Langer Krzysztof Mrózek Claudia D Baldus Andrew J Carroll Bayard L Powell Jonathan E Kolitz Richard A Larson Clara D Bloomfield
- Networks:
- Study
- Multiple Studies, or Legacy Studies in Alliance Study:
- CALGB-19808, CALGB-20205, CALGB-20502, CALGB-8461, CALGB-9621, CALGB-9665
- Phases:
- 1, 3, N/A
- Keywords:
- Adult, Antineoplastic Combined Chemotherapy Protocols, Biomarkers, Tumor, DNA-Binding Proteins, Female, Gene Expression Profiling, Gene Expression Regulation, Neoplastic, Humans, Leukemia, Myeloid, Acute, Male, Middle Aged, Predictive Value of Tests, Prognosis, Proportional Hazards Models, Reverse Transcriptase Polymerase Chain Reaction, Risk Assessment, Statistics, Nonparametric, Stem Cell Transplantation, Survival Analysis, Trans-Activators, Transcriptional Regulator ERG, Up-Regulation