Chromosome 5q deletion and epigenetic suppression of the gene encoding alpha-catenin (CTNNA1) in myeloid cell transformation.
- Citation:
- Nat Med vol 13 (1) 78-83
- Year:
- 2007
- Type:
- Manuscript
- Funding:
- NCTN
- Endpoint:
- Secondary
- Analysis:
- Primary
- Data Sharing:
- No-Data-Sharing
- Status:
- Presented/Published
- Citation Status:
- pub
- Note:
- Methodological:
- No
- Biospecimen:
- Yes
- SDC:
- No
- Book Volume:
- Parents:
- None
- Children:
- None
- Program:
- TRP
- Primary Committee:
- Leuk Corr Sci
- Sec. Committees:
- Pharmas:
- Grants:
- CA101140, CA104987, CA108631
- Corr. Author:
- Authors:
- Ting Xi Liu Michael W Becker Jaroslav Jelinek Wen-Shu Wu Min Deng Natallia Mikhalkevich Karl Hsu Clara D Bloomfield Richard M Stone Daniel J DeAngelo Ilene A Galinsky Jean-Pierre Issa Michael F Clarke A Thomas Look
- Networks:
- Study
- Multiple Studies, or Legacy Studies in Alliance Study:
- CALGB-8461, CALGB-9665
- Phases:
- N/A
- Keywords:
- Acute Disease, Blotting, Western, Cell Line, Cell Line, Tumor, Cell Transformation, Neoplastic, Chromosome Deletion, Chromosomes, Human, Pair 5, DNA Methylation, Flow Cytometry, Gene Expression Regulation, Neoplastic, Green Fluorescent Proteins, HL-60 Cells, Humans, Hydroxamic Acids, In Situ Hybridization, Fluorescence, K562 Cells, Leukemia, Myeloid, Mutation, Myelodysplastic Syndromes, Myeloid Progenitor Cells, Reverse Transcriptase Polymerase Chain Reaction, Transfection, U937 Cells, alpha Catenin